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50 results for “Inflammatory Cytokines”
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Research ArticleOpen accessPhrase in the titleEffect of Combined Fenofibrate and Nicotinamide on Oxidative Stress and Inflammatory Cytokines Involved in Cisplatin-Induced Nephrotoxicity in RatsOmaima M. Abd Allah, Abeer A.I. Sharaf El-Din, Fouad El DebakeyCisplatin (Cis) is an anticancer drug, which is accompanied with major side effects including nephrotoxicity. The current study was performed to assess the possible prophylactic effects of fenofibrate (FEN), Nicotinamide (NAM) and their combination on oxidative stress and inflammatory cytokines associated with cisplatin-induced renal damage. Rats were randomly divided into seven groups (8 each) as follows; control group; FEN group … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 9 Jan 2015 · 7,128 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleAssessment of Therapeutic Effects of Platelet-Rich Plasma in Knee Osteoarthritis: Possible Role of Inflammatory CytokinesMohammed H. Hassan, Sawsan Abuhamdah et al.Osteoarthritis (OA) is a multifactorial disease that commonly affects the knee. Tumor Necrosis Factor-α (TNF-α) regulates inflammation during OA. Macrophage Migration Inhibitory Factor (MIF) may be involved in the pathophysiology of arthritis. Platelet-Rich Plasma (PRP) may reduce pain associated with OA. The present study assessed the possible therapeutic effects of PRP in patients with OA of the knee with varying … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 15 Jun 2021 · 6,987 accessesView PDFCite
Research ArticleOpen accessIn the keywordsInfluence of Probiotics on Coccidia, H. Contortus and Markers of Infection in GoatsKwaku Barima Gyenai, Mulumebet Worku, Mehrdad Tajkarimi, Salam IbrahimImmunostimulants can induce nonspecific resistance against parasites. The use of probiotics to control development of animal gastrointestinal parasites could help reduce the risks of infestation. In this study, we investigated the effects of probiotics administration on gastrointestinal parasites coccidia, H. contortus and markers of infection. A cocktail of probiotics mix including Bifidobacterium longum, Bifidobacterium breve, Lactobacillus acidophilus, Lactobacillus reuteri and … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 29 Jul 2016 · 9,028 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAdaptation to High Grain Diets Proceeds Through Minimal Immune System Stimulation and Differences in Extracellular Matrix Protein Expression in A Model of Subacute Ruminal Acidosis in Non-lactating Dairy CowsB. W. McBride, O. AlZahal, M. A. Steele, L. DionissopoulosProblem statement: Subacute Ruminal Acidosis (SARA) is a metabolic disorder affecting approximately 20% of all dairy cattle in North America. Although the presence of SARA has been described for some time, the etiology of the disorder remains uncertain. For example, many animals diagnosed with SARA seem to remodel and adapt their epithelium to accommodate the stresses imposed by SARA, but … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 2 · 25 Jul 2012 · 8,118 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of a Prophylactic Dose of Ibuprofen on Plasma Level of Interleukin 1, Interleukin 6 and Tumor Necrosis Factor-Alpha in a 1500 m Running PracticeGholamreza Sepehri, Mohammad Pourranjbar, Ghollam-Reza Moshtaghi-Kashanian et al.Problem statement: there are controversies about the effects of anti-inflammatory drugs on exercised induced changes on plasma cytokines in untrained male athletes, so the primary purpose of this study was to measure the influence of a prophylactic dose of ibuprofen use on plasma cytokines during a 1500 m running race. Approach: Subjects were 10 untrained male Medical University students who … …American Journal of Applied Sciences, Vol. 8, Issue 1 · 31 Jan 2011 · 7,886 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear CellsMadhavan P.N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi, C. N. RamchandProblem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NFκB and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin exerts anti-HIV activity by differential modulation of pro-and anti-inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 12,184 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of Gliflozin Therapy on TNF-α Secretion by Cultured Monocytes in Patients with DiabetesTatiana Vladimirovna Kirichenko, Leyla Azimovna Bochkareva et al.Currently it’s well established that chronic inflammation is a key pathogenetic mechanism in the development of Type 2 diabetes. The study aims to explore the inflammatory response of monocytes in diabetic patients compared to healthy subjects, focusing on TNF-α and to investigate the impact of SGLT2 inhibitors on monocyte inflammation. The study included 20 patients with newly diagnosed type 2 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 4,819 accessesView PDFCite
Research ArticleOpen accessIn the keywordsInvestigation of Inflammatory and Oxidative Stress Biomarkers in Multi Vessels Minimally Invasive Coronary Artery Bypass Graft Surgery Versus Off-Pump Coronary Artery Bypass GraftMohammed Farouk Abdel-Hafez, Ahmed El-Minshawy, Ahmed M. Taha et al.Traditional Coronary Artery Bypass Graft (CABG) is currently among of the chief methods in dealing with patients suffering from atherosclerotic coronary heart disease. The current study aimed to measure and compare the levels of proinflammatory cytokines and oxidative stress marker in patients who underwent multivessels Minimally Invasive Coronary Artery Bypass Graft Surgery (MICS– CABG) versus off-pump Coronary Artery Bypass Grafting … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 29 Sep 2021 · 6,170 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSoluble CD14, Sialic Acid and L-Fucose in Breast Milk and their Role in Increasing the Immunity of Breast-Fed InfantsGhalib Ali Oriquat, Tahia H. Saleem, Samir T. Abdullah et al.Problem statement: Breast milk contain protective factors as soluble CD14, L-Fucose and Sialic acid which increase the innate immunity and level of intelligence, decrease the incidence of gastroenteritis, chest and other systemic diseases in newly born infants. In the present study the role of soluble CD14, L-Fucose and Sialic acid, in increasing the immunity in breastfed infants were studied to … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 Apr 2011 · 10,188 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,075 accessesView PDFCite