Research ArticleOpen accessPhrase in the titleINDUCED PLURIPOTENT STEM CELLS AND THEIR IMPLICATION FOR BIOMEDICAL SCIENCESMaria Csobonyeiova, Stefan Polak, Lubos DanisovicThe groundbreaking discovery, that somatic mammalian cells can be epigenetically reprogrammed to a pluripotent state through the exogenous expression of the transcription factors Oct4, Sox2, Klf4 and c-myc, has yielded a new cell type for potential application in regenerative medicine, the induced Pluripotent Stem Cells (iPSCs). Since the first demonstration of creating iPSCs in 2006 great efforts have been made … …OnLine Journal of Biological Sciences, Vol. 13, Issue 4 · 3 Oct 2013 · 7,024 accessesView PDFCite