129 articles for “In-Silico”

Research ArticleOpen accessEvery word in the titlePotential of Fig Leaf (Ficus carica L.) as Immunomodulatory Agent in vitro and in SilicoAnita Dewi, Fitri Rahmayanti, Haidar Bagir et al.Natural remedies are increasingly being used as alternatives to conventional medicine, and their popularity is growing. The fig plant (Ficus carica L.), which is known to contain secondary metabolites such as alkaloids, flavonoids, phenolics, terpenoids, steroids, and saponins, has the potential to act as an immunomodulator. The purpose of this study was to determine the content of flavonoid compounds based … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 19 Jan 2023 · 6,232 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleIn silico Assessment of the Arg85Trp Glucokinase Mutation EffectsFaiza Bouldjennet, Souhila Bouaziz-Terrachet, Malha Azzouz, Rachida RaacheMaturity Onset Diabetes of the Young (MODY) is a heterogeneous group of autosomal dominantly inherited, young-onset β-cell disorders that account for approximately 2% of non-insulin-dependent diabetics in Europe. MODY2 or GCK-MODY is caused by inactivating heterozygous mutations in the glucokinase. Linkage of MODY to the Arg85Trp GCK mutation, among Algerian diabetic patients has been established in our previous research. The … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,808 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleIn silico Modeling of α1A-Adrenoceptor: Interaction of its Normal and Mutated Active Sites with Noradrenaline as well as its Agonist and AntagonistRamchandran Vijayan, Naidu Subbarao, Birendra Nath MallickNoradrenaline, like most other neurotransmitters, acts through various adrenoceptor subtypes. The structure and active site of adrenoceptors for the binding of noradrenaline were unknown, however, such information are crucial for understanding the molecular mechanism of action of neurotransmitters, including noradrenaline, in health and disease as well as for drug designing. In this in silico study, we modeled the α1A-adrenoceptor; a … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 7,140 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleQuality of Sperm Simmental Bulls and Success of Artificial Insemination with the Addition of Nanocalcium Phosphate in Tris Aminomethane Egg Yolk Diluent Using Semen Storage Ampoules from Nanocalcium Silicophosphate BiomaterialsEnike Dwi Kusumawati, I Wayan Karyasa, Yogi Pratama Putra et al.Success in Artificial Insemination (AI) is largely determined by the quality of the stored semen, therefore storage devices, especially straws or ampoules, are an important part that cannot be separated from the overall semen cryopreservation technology. Making a prototype of semen storage ampoules from nanocalcium silicophosphate biomaterials is based on the need for straws or ampoules. Semen storage in spermatozoa … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 28 May 2024 · 5,211 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleSemi-Probabilistic Calibration of a Partial Material Safety Factor for Structural Silicone Adhesives - Part I: DerivationMichael Drass, Michael A. KrausThis paper deals with the application of the semi-probabilistic design concept (level I) of Eurocode 0 in order to calibrate partial safety factors for structural silicone sealants. In the first part of this article the current legal situation for the application of structural sealants in façades is described, where a new Eurocode-conform design concept is introduced and compared to existing … …International Journal of Structural Glass and Advanced Materials Research, Vol. 4, Issue 1 · 2 Mar 2020 · 11,110 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleSemi-Probabilistic Calibration of a Partial Material Safety Factor for Structural Silicone Adhesives - Part II: Verification ConceptMichael A. Kraus, Michael DrassThis paper deals with the application of the semi-probabilistic design concept (level I) to structural silicone sealants where a generally valid verification concept is proposed. The verification concept deals with the classification of silicone adhesive joints into cavitation-insensitive and cavitation-sensitive adhesive joints and at the same time advises which class of material models is necessary for the categorized adhesive joint … …International Journal of Structural Glass and Advanced Materials Research, Vol. 4, Issue 1 · 10 Jan 2020 · 11,269 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titlePreparation of Fluorine/Silicon Co-Modified Elastic Acrylate with Low Fluorine and High PerformanceYuan Zhihua, Xia Chunlei, Geng Ziye et al.The methyl acrylate was modified with hexafluorobutyl methacrylate (G02) and vinyl triethoxy silane (A-151) as modified monomers, Methyl Methacrylate (MMA) as hard monomer and Butyl Acrylate (BA) as soft monomer. Pre-emulsification, seed emulsion and semi-continuous synthesis process were adopted to the effects of the preparation process, the ratio of G02 and A-151 modified monomers, the amount of soft monomer and … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 4 Jan 2020 · 7,651 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titlePreparation of Porous Silicon P-Type and Thermal Diffusivity Measurement Using Photoacoustic TechniqueMohammed Jabbar Hussein, Suaad Sahib Hindal, Amany Akram AwaadPorous silicon (PSi) layers were formed on a p-type Si wafer. Electrochemical method was used to prepare 36 samples with three values of current density (10, 20 and 30) mA/cm2, each involved ( 20, 40, 60 and 80) min etching times the samples were heated to three selected temperatures of 100, 200 and 350°C in three groups. The first group … …International Journal of Structural Glass and Advanced Materials Research, Vol. 2, Issue 1 · 14 Nov 2018 · 7,437 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleSTUDY OF THE POSSIBILITY OF POLYTYPE 3C SILICON CARBIDE BULK CRYSTALS GROWING FOR USE IN POWER DEVICESLebedev Alexander Alexandrovich, Bulat Pavel ViktorovichDue to its electro-physical parameters, the silicon carbide is a promising material for power devices, including the microwave range. In recent years there has been considerable progress in the development of power devices, based on SiC. Serious problem, which hinders the widespread commercialization of SiC bipolar power devices, is the p-n structures degradation during high densities of passing forward current. … …American Journal of Applied Sciences, Vol. 11, Issue 10 · 5 Dec 2014 · 6,348 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAsymptotic Giant Branch Stars Migration from the Central of the Milky Way Galaxy to our Sun’s Birthplace and its Relation with Silicon Carbide GrainsAhmad Hashem AbdelhadiSilicon carbide grains found in meteorites are peculiar in their age and isotopic ratios; they formed before the Sun was born and their isotopic signature indicates that they come from a different galactic region. This study aims to seek a possible paradigm for such richness and peculiarity through Monte Carlo simulation of scattering of Asymptotic Giant Branch (AGB) stars off … …Space Science International, Vol. 1, Issue 1 · 20 Jun 2013 · 7,053 accessesView PDF Cite