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3 articles for “Hypoxia-Inducible Factor 1”
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Research ArticleOpen accessPhrase in the titleHypoxia-Inducible Factor 1α Expression in Chorionic Tissue and Decidua of Women with Spontaneous Abortion at the First Trimester of PregnancyE. V. Mashkina, K. A. Kovalenko, E. V. ButenkoOxygen-regulated genes expression has important role in pre-implantation embryonic metabolism regulation. Hypoxia Inducible Factor (HIF) regulated by hypoxia oxygen tension is crucial for placenta development. But the data about its role in spontaneous abortion is very poor. Thus, we aimed to determine an expression level of HIF-1α in chorionic tissue and decidua at pregnancy. Samples of chorionic tissue and decidua … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 18 Nov 2014 · 6,862 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Hypoxia-Inducible Factor-1α Signaling Pathway and its Relation to Cancer and ImmunologyBruno R.B. Pires, Andre L. Mencalha, Gerson M. Ferreira et al.Hypoxia-Inducible Factor 1 (HIF-1) is a transcription factor that is present in all metazoans from early embryonic development throughout adult life. It plays a major roles in the different stress responses that are triggered by low Oxygen (O2) levels and its expression is associated with cell survival. HIF-1 is a heterodimer protein that comprises the subunits HIF-1α and HIF-1β. The … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 8,482 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Functional Analysis of the Basic Helix-Loop-Helix Proteins in the Clawed Frogs' Genomes With Common Essential Pathways and Enriched Gene Ontology TermsWuyi LiuThe international Gene Ontology (GO) and pathway databases were used to functionally analyze the clawed frogs' Basic Helix-Loop-Helix (bHLH) transcription factors of Xenopus tropicalis and Xenopus laevis in a updated genome-wide survey. There were 41 GO terms and one pathway significantly enriched for Xenopus tropicalis, whereas there were 45 GO terms and 3 pathways significantly enriched for Xenopus laevis. Among … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 1 · 28 Mar 2019 · 8,490 accessesView PDFCite