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6 results for “Human Leukocyte Antigen”
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Research ArticleOpen accessPhrase in the titleHow Micrornas Affect the Expression of Human Leukocyte Antigeng in PregnancyAyla Carmel Kempers, Marie Van Dijk, Cees OudejansThe expression of Human Leukocyte Antigen G (HLA-G) on Fetal Extravillous Trophoblast (EVT) cells during pregnancy plays an important role in preventing the fetus from rejection by suppressing the maternal immune system. Decreased expression levels of HLA-G have already shown to be associated with several complications of pregnancy such as pre-eclampsia. However, it remains largely unknown how HLA-G gene expression … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 7,126 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Association of HLA Class II Alleles with the Response to Alfa-Interferon/Ribavirin Therapy in Chronic Hepatitis C PatientsAwny Aly Abol-Ez Gawish, Nahla Abd El-Hamid Mohammed, Rasha Adel Sayed Ahmed Hussein, Elsaid Galal El-BadrawyHuman Leucocyte Antigens (HLA) class II appears to play an important role in the individual’s immune response to viral infection. The present study was aimed at assessment of the relationship between HLA DRB1 alleles and the response to HCV combined therapy in Chronic Hepatitis C patients (CHC). We enrolled a total of 44 chronically infected HCV patients without Hepatitis B … …American Journal of Immunology, Vol. 11, Issue 3 · 12 Nov 2015 · 6,704 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCo-Inhibitory Molecule Programmed Death-1 and its Ligands: A New Alternative Therapy for Human Immunodeficiency Virus Infection?A. Leon-Flores, P. Del Rio, G. Reyes-TeranChronic viral infections are characterized by the up-regulation of a set of immunomodulatory receptors. The over-expression of co-inhibitory molecules on T cells leads to a dysfunctional T cell response with an "exhausted" phenotype. Programmed Death-1 (PD-1) is a molecule that exerts an inhibitory signal on the T cell receptor when it binds to the PD-L1 or PD-L2 ligands present on … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 28 Dec 2012 · 6,965 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship Between Antibodies to Toxocara and the Disability of the Human Ankylosing SpondylitisFrancisco-Javier Jiménez-Balderas, Patricia Méndez-Samperio, Raquel Tapia-Romero, Jorge-Luis de-la-Rosa-AranaThere are only few studies reported in the literature of patients with spondyloarthropathies associated with Toxocara infection. Thus, the aim of this work was to investigate the relationship between antibodies to Toxocara and the disability of the human Ankylosing Spondylitis (AS). Thirty-six AS patients (14 female and 22 male) participated during the study period and all were residents from Mexico … …American Journal of Infectious Diseases, Vol. 11, Issue 1 · 29 May 2015 · 6,891 accessesView PDFCite
Research ArticleOpen accessIn the abstractActin Cytoskeleton and Related Proteins Role During Immune Cells Migration, Polarity and Activation: An OverviewClaudio Vieira da SilvaImmune cells migration, polarity and activation are essential during host immune response. Upon recognition of specific peptides presented by Human Leukocyte Antigen (HLA) molecules on Antigen Presenting Cells (APC), lymphocytes execute subset-related functions such as killing, help and regulation. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation … …American Journal of Immunology, Vol. 9, Issue 4 · 19 Nov 2013 · 6,783 accessesView PDFCite
Research ArticleOpen accessIn the abstractFlow Cytometry Baseline on Peripheral Leukocyte Cell Profiles for Dairy Goat KidsDarcy M. Fletcher, Megan B. Vogt, Hannah E. Pirner et al.Small ruminants, like goats, would make excellent animal models for not only infectious diseases in large ruminants but also analogous diseases in humans, such as human tuberculosis, Crohn’s disease, melioidosis and brucellosis. The main disadvantage for the small ruminant model is the lack of sufficient baseline data on normal, healthy goat kids. Furthermore, most reagents (antibodies and the like) were … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 26 Sep 2013 · 7,576 accessesView PDFCite