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6 results for “Glutamate Receptors”

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Research ArticleOpen accessPhrase in the titleBlockade of Group I Metabotropic Glutamate Receptors (mGluRs) Activation Inhibits Nociception Following Descending Colon Distension in SheepBogdan F. Kania, Danuta Wrońska, Mikołaj A. GralakExpression of mGluRs of groups I and II was found in structures of CNS closely related with nociception: spinal cord superficial fields, responsible for pain filling or modulation of neurotransmission in the peripheral receptors. The present study examined contribution of mGluRs to the development and maintenance of changes in behavioral and clinical symptoms caused by visceral pain. Experiments were carried … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 7,427 accessesView PDFCite
Research ArticleOpen accessIn the keywordsNeuronal Necrosis Due to a Lethal Epileptic Syndrome Affecting FVB Strain β-Actin Luciferase Transgenic MiceAhmed Shoieb, Rachel Allavena, Abdelazim IbrahimThe FVB is the most often inbred mouse strain used in transgenic research. This strain is recognised to be affected with a disease known as FVB Lethal Epileptic Syndrome (FLES). A case series of FVB mouse lethal epileptic syndrome in a cohort of commercially procured β actin luciferase transgenic FVB mice was diagnosed based on the clinical signs, post-mortem and … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 10 Dec 2014 · 7,482 accessesView PDFCite
Research ArticleOpen accessIn the abstractDifferent Arrangement of Dopamine Receptors/NMDA Receptors Heterocomplexes in the Brain Regions of a Healthy Male, Female and Audiogenic Seizure-Prone Male RatsGigi Tevzadze, Elene Zhuravliova, Natia Okriashvili et al.Differences in the composition and subcellular localization of heteroreceptors in the brain can trigger central nervous system diseases, including epilepsy and autism. Protein-protein interactions between Dopamine Receptors (DRs) and GLUN2A and GLUN2B subunits are critical mechanisms that regulate dopamine and glutamate coordinated signals. These interactions may be involved in the pathophysiological predisposition of epilepsy. We hypothesized that the specificity of … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 27 Apr 2022 · 6,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractCastration and Passive Avoidance Learning Alter the Distribution of N-Methyl D-Aspartate ReceptorSeyed Hassan Mirzaei, Mahnaz Taherianfard, Mina Tadjali, Mahbobeh KohkaloyehIn neurophysiological studies on learning and memory, L-glutamate receptors especially N-Methyl, D-Aspartate glutamate (NMDA) receptors have a major role in different aspect of the learning and memory. Two sites of mammalian brain that show high density of these receptors are CA1 region of hippocampus and Purkinje cell layer of cerebellum. Twenty four Sprague-Dawley rats were used in 4 groups: Control … …Neuroscience International, Vol. 4, Issue 2 · 1 Apr 2014 · 6,773 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrenatal Exposure to Chronic Ethanol on N Methyl D Aspartate Receptor DistributionM. Taherianfard, B. Geramizadeh, E. Evazi, M. SharifiProblem statement: Effect of chronic exposure to ethanol on NR1 subunit of the NMDA receptor distribution in chick embryo brain chronic ethanol intake leads to the development of dependence on and tolerance to ethanol in both human and animals. The glutamate system plays a major role in mediating ethanol effects on brain and behavior. The aim of the present study … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,301 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordTaurine Implicated in Bromocriptine Induced Hallucination: Glycine-Glutamic-Aspartic Implicated in Bromocriptine Induced SchizophreniaAbdulrahim Abu JayyabProblem statement: The literature is reviewed and supports a strong anecdotal relationship between bromocriptine use and psychosis. It is well known that any interference with brain amino acid levels is likely to lead to disorder. Our previous research has shown that bromocriptine produced significant changes in the heart and kidneys amino acid contents. It has been confirmed that the brain … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 8,032 accessesView PDFCite