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21 articles for “Genetic Variants”

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Research ArticleOpen accessEvery word in the titleMarking of Genetic Resistance to Chlamydia, Brucellosis and Mastitis in Holstein Cows by Using Polymorphic Variants of LTF, MBL1 and TLR9 GenesIndira Beishova, Birzhan Nurgaliyev, Alena Belaya et al.The purpose of the research is to study the association of polymorphic variants of the Toll-Like Receptor 9 (TLR9), Mannose-Binding Lectin 1 (MBL1), and Lactoferrin (LTF) genes with the incidence of chlamydia, brucellosis and mastitis in Holstein cows. Samples of Holstein cows with established diagnoses of chlamydia, brucellosis, and mastitis were characterized by the nature of the correspondence of the … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 2 · 6 May 2023 · 6,157 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEvaluation of Polymorphisms at Heat Shock Protein 90 Gene by High Resolution Melting Assays for Potential Heat Tolerance among Nigerian Zebu Cattle BreedsGbolabo Onasanya, George Msalya, Aranganoor Thiruvenkadan et al.Heat Shock Protein (HSP) 90 gene is a member of HSPs sub-family that act as molecular chaperons whenever animals come under thermal stress. The genes fulfill essential roles of providing cellular protection, immune response, protein synthesis, protein folding and unfolding, protection from cellular stress, inhibitory apoptosis and adaptation. This study was designed to analyze polymorphisms of HSP 90 and to … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 1 · 7 Mar 2020 · 7,258 accessesView PDFCite
Review ArticleOpen accessIn the abstractGoats’ Litter Size Concerning Bone Morphogenetic Protein 15 Gene VariationsTebogo Letsukulo Percy Thepa, Thobela Louis Tyasi, Jones Ng’ambiBone morphogenetic protein 15 (BMP15), a member of the transforming growth factor-β (TGF-β) superfamily, plays essential roles in follicular development and ovulation. Single nucleotide polymorphisms (SNPs) in the BMP15 gene have been associated with litter size in multiple livestock species, yet no comprehensive systematic review has synthesized findings across goat breeds. This systematic review aimed to evaluate the association between … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 18 Feb 2026 · 1,405 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Review ArticleOpen accessIn the abstractInsulin-Like Growth Factor 1 Gene and Growth Traits Correlations in Sheep: A Systematic ReviewThabang Sako, Thobela Lousi Tyasi, Jones Ng’ambiAbousoliman, I., Reyer, H., Oster, M., Muráni, E., Mourad, M., Abdel-Salam Rashed, M., Mohamed, I., & Wimmers, K. (2020). Analysis of Candidate Genes for Growth and Milk Performance Traits in the Egyptian Barki Sheep. Animals, 10(2), 197. https://doi.org/10.3390/ani10020197 Al Qasimi, R., Hassan, A., & Khudair, B. Y. (2019). Effect of IGF-1 and GH Genes Polymorphism on Weights and Body Measurements … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 25 May 2024 · 5,755 accessesView PDFCite
Literature ReviewOpen accessIn the abstractSystematic Review of Single Nucleotide Polymorphisms of Cattle Beta-Lactoglobulin Gene and their Association with Milk Production TraitsThlarihani Cynthia Makamu, Thobela Louis TyasiThe application of molecular genetics technology to pinpoint certain DNA markers associated with commercially significant features is highly anticipated since it has the potential to enhance the effectiveness of breeding programs by selecting young animals early for use as future breeding stock. One of the main genes expressed in bovine milk is the Beta-Lactoglobulin Gene (βLG), and its polymorphism can … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 4 Mar 2024 · 5,811 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of Diplotypes Associated with Meat Productivity in Cattle Breeds Common in the Territory of the Republic of KazakhstanAskar Mirzahmetovich Nametov, Indira Saltanovna Beishova, Alena Valentinovna Belaya et al.Technologies for genetic labeling of economically useful traits using polymorphic variants of genes that control the rate of growth and development of animals make it possible to assess the genetic potential of an animal immediately after birth, which significantly reduces time and financial costs. This study aimed to identify paired combinations of the genes growth hormone, growth hormone receptor, and … …OnLine Journal of Biological Sciences, Vol. 22, Issue 3 · 17 Aug 2022 · 6,187 accessesView PDFCite
Research ArticleOpen accessIn the abstractCreation of a New Highly Productive Parent Material of Sweet Clover (Melilotus Adans.) based on Varietal and Microbial SystemsN.I. Filippova, I.V. Rukavitsina, E.I. Parsayev et al.The paper presents the results of studies carried out on the experimental field of Research and Production Center of Grain Farming named after A.I. Barayev Limited Liability Partnership for the creation of new parent material for yellow sweet clover (Melilotus officinalis (L.) Pall.) and Volga sweet clover (Melilotus wolgicus Poir.) based on varietal and microbial systems. The studies were carried … …OnLine Journal of Biological Sciences, Vol. 22, Issue 2 · 13 Apr 2022 · 5,847 accessesView PDFCite
Research ArticleOpen accessIn the abstractConservation of Binding of Llama and Other Animals’ Hemoglobins to Haptoglobins Across SpeciesMoges Woldemeskel, Oluseyi A. VanderpuyeThe plasma protein haptoglobin binds hemoglobin released from lysed erythrocytes. It causes removal of the free hemoglobin, thus preventing pathological oxidation of cells. Hemoglobin higher level structures are well conserved across animal species but primary structures can be as little as 50% homologous. Because of these differences, the question arose as to what extent hemoglobins can bind to haptoglobins from … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 1 · 26 Jan 2018 · 9,200 accessesView PDFCite
EditorialOpen accessIn the abstractBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,755 accessesView PDFCite