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10 articles for “Gene Silencing”
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Research ArticleOpen accessPhrase in the titleMagnum Opus: Clustered Regularly Interspaced Short Palindromic Repeats Biology and Prokaryotic Gene SilencingPrem Saran Tirumalai, Ashim Kumar BagchiGene Silencing was a technology that was established in eukaryotic system a decade ago and is being used as a research tool widely. However, prokaryotic gene silencing was not workable, till recently a team of researchers from the University of Georgia have proved it possible. Where they have shown that short motif sequences determines the targets of the prokaryotic Clustered … …American Journal of Immunology, Vol. 9, Issue 4 · 5 Oct 2013 · 7,144 accessesView PDFCite
Review ArticleOpen accessIn the keywordsAdvances in Modern Biotechnological Tools for Sustainable Control of Plant Viral DiseasesNabela Akter, Ankita Saha, Md. Abdullah Al Sabbir, Md. Motaher HossainPlant viruses pose a major threat to global food production, causing yield losses across many staple and horticultural crops. Conventional breeding for resistance is typically slow and constrained by the number of available natural resistance genes. Recent breakthroughs in biotechnology have enabled the development of accurate, flexible, and environmentally friendly technologies to confer virus resistance. This review summarizes exciting developments … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 16 Jul 2026 · 726 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGENE IMPRINTING: ENGRAVING THE PATHOGENESIS OF HERIDETARY DISEASESSandeep Satapathy, Roshan Kumar Singh, Harikrishnan RajendranGene imprinting has conduited the scope of our understanding of phenotypic expression and its corelation with constituent genotype. It is an epigenetic process that involves DNA methylation and histone modulation to attain monoallelic gene expression without altering the genetic sequences. A distinctive model of non-mendelian genetics, imprinting extends the control over expression of traits and selection of the allele that … …American Journal of Immunology, Vol. 10, Issue 1 · 12 Feb 2014 · 7,682 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffects of ced-9 dsRNA on Caenorhabditis elegans and Meloidogyne incognitaRobert T. Gaeta, Abdellatif Bahaji, Glenda W. Polack, Alejandro Calderón-UrreaAbstract: Problem Statement: In metazoans Programmed Cell Death (PCD) is essential for proper development. Suppression of PCD is needed to guarantee cell survival and in the nematode Caenorhabditis elegans the regulation of PCD is accomplished by the function of the ced-9 gene. Approach: In this work the use of double stranded RNA (dsRNA) to knock-down ced-9 gene function was tested … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 1 · 15 Dec 2010 · 9,452 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Silencing of Septin 1 via Synthetic siRNAs in Schizosaccharomyces pombeSemih Ekimler, Merve Yilmazer, Ercan AricanSeptins are evolutionary conserved GTP-binding proteins and form heterooligomers in cells to interact with cytoskeleton. The main roles of septins in cell are cytokines, membrane interactions, vesicle trafficking and microtubule and actin organization. Non-coding RNAs are key players of gene expression regulation. Small-interfering RNAs (siRNAs) belong to non-coding RNAs, are characterized by sequence complementarity to their target mRNAs. siRNAs silence … …OnLine Journal of Biological Sciences, Vol. 17, Issue 1 · 31 Mar 2017 · 7,237 accessesView PDFCite
EditorialOpen accessIn the abstractThe Timeless Contribution of Rootstocks towards Successful Horticultural Farming: From Ancient Times to the Climate Change EraIoannis E. PapadakisGrafting is a horticultural practice by which living vegetative plant organs (root, stem and/or buds) of either the same genotype or, usually, different genotypes belonging to the same species, genus, subfamily and/or family, are tightly connected to each other to form a double-compound plant. In fact, it is a method of asexual (clonal-vegetative) propagation of plants. The basal part of … …American Journal of Agricultural and Biological Sciences, Vol. 11, Issue 4 · 16 Dec 2016 · 9,521 accessesView PDFCite
Research ArticleOpen accessIn the abstractCloning and Functional Analysis of tri14 in Trichoderma brevicompactumXu-Ping Shentu, Xiao-Feng Yuan, Wei-Ping Liu et al.Trichodermin, one of the trichothecenes, is a potential antifungal antibiotic and a protein synthesis inhibitor. Trichodermin is synthesized mainly by Trichoderma brevicompactum, but the biosynthetic pathway has yet been completely elucidated. Our earlier transcriptome assay on the trichodermin synthesis in T. brevicompactum 0248 identified a unique tri14 transcript, designated Tbtri14, that was co-regulated with other tri cluster genes. However, the … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 25 Aug 2015 · 7,393 accessesView PDFCite
Review ArticleOpen accessIn the abstractHypermethylation and Hypomethylation of DNA: Implication for Diagnosis and Prognosis of Prostate CancerLubos Danisovic, Stanislav ZiaranProstate cancer belongs to the most common cancers and it is the second leading cause of cancer death in men. A genetic predisposition with epigenetic changes in DNA contributes to the development of the disease. DNA hypermethylation and hypomethylation belong to the most studied epigenetic changes in prostate cancer development. Both forms may lead to chromosomal instability and transcriptional gene … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 13 Jun 2015 · 6,528 accessesView PDFCite
EditorialOpen accessIn the abstractCRISPR-CAS SYSTEM: A FEASIBLE SOLUTION FOR GETTING RID OF PERSISTENT VIRAL INFECTION?Zhaohua ZhongMany viruses, including DNA and RNA viruses, can persistently replicate in the infected cells and cause a prolonged damage. Herpes viruses can be latent in its host cells. Human Immunodeficiency Virus (HIV) reversely transcripts its RNA genome to DNA and integrates to the host’s chromosome. Hepatitis B Virus (HBV) and Human Papilloma Virus (HPV) persistently stay in the host cells … …Current Research in Virology, Vol. 3, Issue 1 · 10 Nov 2014 · 12,614 accessesView PDFCite
Research ArticleOpen accessIn the abstractInduced Production of α-Tocotrienol by Co-Suppression of Tocopherol Cyclase Gene in Vegetable CropsUmaiyal Munusamy, Siti Nor Akmar Abdullah, Maheran Abdul Aziz et al.This study involves the induced production of α-tocotrienol by the co-suppression of tocopherol cyclase gene. The Tocopherol/Tocotrienol Cyclase (TC) is a key enzyme involved in the biosynthesis of α-tocotrienol. The partial conserved cDNA of TC gene isolated from the oil palm (Elaeis guineensis) that shared greater than 75% sequence identity with TC sequences from other plant species was used to … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,706 accessesView PDFCite