2 results for “Gaussian Interaction Profile Kernel”

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Research ArticleOpen accessIn the keywordsKRLSMDA: Identifying Human miRNA–Disease Association Based on Similarity and Kronecker Regularized Least Squares MethodLingzhi Zhu, Weimin Gao, Guixiang Li et al.A growing number of studies have suggested that miRNAs (microRNAs) have associations with human diseases, the design and discovery of drug. But so far, we do not yet fully understand the molecular mechanism of miRNAs in the development of human diseases. Predicting miRNA-disease associations is helpful for understanding the molecular mechanism of miRNAs in the development of human diseases. However, … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 1 · 15 Mar 2021 · 6,403 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsPredicting Microbe-Drug Association based on Similarity and Semi-Supervised LearningLingzhi Zhu, Jun Wang, Guixiang Li et al.Increasing clinic evidences have showed that microbial communities play important roles in human health and disease. Predicting hidden microbe-drug associations can be helpful in understanding the microbe-drug association mechanisms in clinical treatment, drug discovery, combinations and repositioning. Some computational methods were proposed to predict the associations of microbes and drugs. However, the prediction performance of these methods needs to be … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 1 · 9 Mar 2021 · 7,535 accessesView PDF Cite