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13 articles for “GST”
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Research ArticleOpen accessIn the keywordsPolycyclic Aromatic Hydrocarbon Accumulation and Biomarker Responses in Cockles from Moroccan Mediterranean CoastsIkram Chbani, Saida Bouzid, Nourredine Bouayad, Hassan Er-RaiouiThis study aims to evaluate levels and effects of Polycyclic Aromatic Hydrocarbons (PAHs) in cockles (Acanthocardia tuberculatae) collected from two differently influenced areas in the Mediterranean Western Moroccan coasts. PAHs accumulation was studied in soft tissues using Soxhlet extraction and separation on silica column methods. The measure of those organic compounds was realized by Gas chromatography coupled to Mass spectrometer … …American Journal of Environmental Sciences, Vol. 15, Issue 4 · 30 Jul 2019 · 7,497 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,423 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Association of Early Pregnancy Loss with Polymorphism in Xenobiotics Detoxification GenesElena Vladimirovna Mashkina, Konstantin Nikolaevich Saraev, Elena Viktorovna Butenko et al.Pregnancy loss and other pregnancy complication can be connected with environmental and lifestyle risk factor, among which effect of chemical compounds is the strongest. Effects of xenobiotics can be modified by allele variants of xenobiotic detoxification enzymes phase I or II. A total of 71 women with early pregnancy loss and 101 control patients were examined by a case-control methodology. … …American Journal of Applied Sciences, Vol. 12, Issue 3 · 6 May 2015 · 7,032 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLack of Association of Glutathione S-transferase Gene Polymorphisms in Iranian Prostate Cancer SubjectsB. Sahar Ansari, R. Vasudevan, M. Mirinargesi et al.Problem statement: Glutathione S-transferase is super family genes that encode enzymes which involve in the detoxification of the cell and protects DNA from damage. Conflicting results was found in several studies in association with GSTT1 and GSTM1 gene polymorphisms and prostate cancer. In this study, we determined the association between the GSTT1 and GSTM1 gene polymorphism and prostate cancer in … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,273 accessesView PDFCite
Research ArticleOpen accessIn the keywordsImmobilized Whole Cell System with Methyl Parathion-Degrading Activity for Organophosphate Insecticide DetectionChadaporn Pootawee, Witsanu Senbua, Jesdawan WichitwechkarnAs the result of the extensive use and high contamination of organophosphate (OP) insecticides in agricultural products and the environment, especially in developing countries, a simple and convenient means for OP detection and screening was investigated. Whole cells from the recombinant clone BpGP carrying methyl parathion (MP) degrading, mpdB, gene originating from MP-degrading Burkholderia cepacia and possessing MP-degrading activity were … …OnLine Journal of Biological Sciences, Vol. 18, Issue 3 · 18 Sep 2018 · 7,673 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreparation, Identification and Antioxidant Evaluation of Citrullus Colocynthis Root and Fruit Extracts Against Doxorubicin in Male RatsSarah Samir Othman, Gamal M. Hamad, Sabria Abo Zaid Hassan et al.Millions of people are affected by diseases in developing or developed countries. Citrullus colocynthis is a high-antioxidant wildflower, it is healthy to eat and may be used as a source of energy or medication. The goal of this research was to conduct a phytochemical analysis of Citrullus colocynthis fruit extract, which is abundant in Egypt. Different extracts from that plant … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 8 Feb 2022 · 6,243 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic State of Pulsatilla Patens (L.) Mill. Coenopopulations Based on DNA LabelingRustem Saltanovich Beishov, Gulnar Sultangazina, Indira Saltanovna Beishova et al.In the article, the results of studying the gene pools of the Kazakhstan coenopopulations of a rare plant species Pulsatilla patens (L.) Mill. are shown. The biomaterial taken from five coenopopulations located in Northern Kazakhstan has been used as samples. To identify the multilocus DNA polymorphism, the authors have used ISSR (Inter Simple Sequence Repeats, or intermicrosatellite analysis) labeling. The … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 2 Apr 2021 · 5,944 accessesView PDFCite
Research ArticleOpen accessIn the abstractNon-Target Inhibition of Antioxidant Enzymes in Honey Bees (A. mellifera and A. florea) Upon Pesticide ExposureAmal Ahmed Berjawi, Syed Salman Ashraf, Mohammad Ali Al-DeebUnderstanding how different insecticides influence bee health is very essential. The aim of this work was to evaluate enzyme kinetics and inhibition by insecticides in Apis mellifera and Apis florea. Tested enzymes showed variable affinity to substrates. In A. florea, glutathione S-transferase (GST) showed significantly higher affinity for its 1-Chloro-2,4-Dinitrobenzene (CDNB) substrate than in A. mellifera. Carbosulfan caused the highest … …OnLine Journal of Biological Sciences, Vol. 20, Issue 2 · 10 Apr 2020 · 7,394 accessesView PDFCite
Research ArticleOpen accessIn the abstractDifferential Activities of Glutathione S-Transferase Isoenzymes in Strains of Fasciola Hepatica Susceptible and Resistant to TriclabendazoleV. Fernández, P. Ortiz, M.V. Solana, H. SolanaFasciolosis, a parasitic zoonosis of intrahepatic location, is caused by the trematode Fasciola hepatica. Its control is mainly based on the use of the anthelminthic Triclabendazole (TCBZ). The indiscriminate use of this drug has favored the development of anthelmintic resistance. The Glutation S-Transferases (GSTs) are multifunctional enzymes involved in the detoxification of xenobiotics and endogenous compounds using conjugation with endogenous … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 10 Dec 2014 · 7,574 accessesView PDFCite
Research ArticleOpen accessIn the abstractPOTENTIAL AMELIORATIVE ROLE OF N-ACETYLCYSTEINE AGAINST TESTICULAR DYSFUNCTION INDUCED BY TITANIUM DIOXIDE IN MALE ALBINO RATSAhmed Farag El-Kirdasy, Mohamed Abdo Nassan, Ahmed Abdel Aziz Baiomy et al.In this study, we examined the ameliorative action of N-Acetylcysteine (NAC) against Titanium Dioxide (TiO2) induced testicular degeneration in albino rats. Adult male albino rats were given saline as a control group, TiO2 (1200 mg kg-1 BW), NAC (100 mg kg-1 BW) and co-treatment of NAC and TiO2 as a protective group for 3 months. Testicular tissues were extracted for … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 31 Dec 2013 · 7,900 accessesView PDFCite