3 results for “GABA agonist/antagonist”

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Research ArticleOpen accessIn the keywordsNeuroprotection Afforded by GABA Against Oxygen-Glucose Deprivation-Induced Injury in Rat Cortical Brain Slices: An Hormetic Dose-Response EffectLorenzo Ricci, Massimo Valoti, Giampietro Sgaragli, Maria FrosiniThe aim of the present investigation was to assess neuroprotection exerted by GABA (100 nM-100 mM) in rat cortical brain slices subjected to oxygen-glucose deprivation and reoxygenation. Neuronal injury and neuroprotection were assessed by measuring the release of glutamate and lactate dehydrogenase and tissue water content. Results demonstrate that GABA exerted neuroprotective effects according to a U-shaped, hormetic-like, concentration-response curve, … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,166 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInteraction of γ Aminobutyric Acid B Receptors and Electromagnetic Field in the Fear ResponseM. Taherianfard, A. Bahaodini, M. Fazeli, S. Karimi HaghighiOne of the most neurotransmission system consistently linked with fear response is GABAergic system. GABA through GABAB receptor can influence fear response. The aim of the present investigation was to examine the effect of IP injection of baclofen (GABAB agonist) and CGP35348 (GABAB antagonist) along with EMF exposure on frequency of fear response. Fifty adult male rats weighing 180-200 g … …Neuroscience International, Vol. 4, Issue 2 · 1 Apr 2014 · 6,691 accessesView PDF Cite

Research ArticleOpen accessIn the abstractElectromagnetic Field and Γ Aminobutyric Acid a Receptors Interaction in the Fear ResponseM. Taherianfard, A. Bahaodini, M. Fazeli et al.Freezing behavior is a fearful reaction to specific stimuli, most commonly observed by animals. One of the neurotransmission system most consistently linked with fear response is the GABAergic system, in which GABA through GABAA receptor can influence fear response. The aim of the present investigation was to examine the effect of IP injection of muscimol (GABAA agonist) and bicuculline (GABAA … …Current Research in Psychology, Vol. 4, Issue 1 · 4 Sep 2013 · 7,515 accessesView PDF Cite