2 results for “Fractionated Radiation”

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Research ArticleOpen accessEvery word in the titleRadiation-Induced Cognitive Dysfunction After Different Schemes of Fractionated Whole Brain IrradiationZorkina Yana Alexandrovna, Zubkov Eugene Andreevich, Yusubalieva Gaukhar Maratovna et al.Radiation-induced cognitive dysfunction is a serious complication of radiation therapy. In humans, numerous cases of radiation damage have been recorded after irradiation for therapeutic purposes. The degree of cognitive dysfunctions and its dependence on biological effective doses should be tested in animal preclinical models to minimize radiation side effects. Fractionated whole brain irradiation was performed according to the following schemes: … …Neuroscience International, Vol. 5, Issue 2 · 14 Jan 2015 · 7,256 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPYIgnacio Fernandez-GarciaRadiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Jul 2014 · 7,459 accessesView PDF Cite