Research ArticleOpen accessEvery word in the titleAtomic Absorption Spectrometric Determination of Certain Fluoroquinolones in Pharmaceutical Dosage Forms and in Biological FluidsH. Salem, W. Khater, L. FadaSimple, accurate, sensitive and selective methods are described for the quantitative determination of ten fluoroquinolones (amifloxacin, ciprofloxacin hydrochloride, difloxacin hydrochloride, enoxacin, enrofloxacin, lomefloxacin hydrochloride, levofloxacin, norfloxacin, ofloxacin and pefloxacin mesylate). The methods are based on precipitation of the ion associates formed from the reaction of the cited drugs with silver nitrate, copper acetate and ferric chloride. The formation and solubility … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,419 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSpectrofluorimetric Determination of Certain Fluoroquinolones Through Charge Transfer Complex FormationH. Salem, L. Fada, W. KhaterA highly sensitive spectrofluorimetric method was developed for the first time, for the analysis of ten fluoroquinolones (FQs) antibacterials, namely amifloxacin (AMI), ciprofloxacin (CIP), difloxacin (DIF), enoxacin (ENO), enrofloxacin (ENR), lomefloxacin (LOM), levofloxacin (LEV), norfloxacin (NOR), ofloxacin (OFL) and pefloxacin (PEF) in their pharmaceutical dosage forms or in biological fluids through charge transfer (CT) complex formation with bromanil (BRO). The … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 1 · 31 Mar 2007 · 7,629 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSpectrofluorimetric Study of the Charge-transfer Complexation of Certain Fluoroquinolones with 2,3,5,6-tetrafluoro-p-bezoquinoneD. Geffken, H. SalemA highly sensitive spectrofluorimetric method was developed for the first time, for the analysis of ten fluoroquinolones (FQs) antibacterials, namely amifloxacin (AMI), ciprofloxacin (CIP), difloxacin (DIF), enoxacin (ENO), enrofloxacin (ENR), lomefloxacin (LOM), levofloxacin (LEV), norfloxacin (NOR), ofloxacin (OFL) and pefloxacin (PEF) in their pharmaceutical dosage forms or in biological fluids through charge transfer (CT) complex formation with fluoranil (TFQ). The … …American Journal of Applied Sciences, Vol. 3, Issue 8 · 31 Aug 2006 · 6,715 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSpectrofluorimetric, Atomic Absorption Spectrometric and Spectrophotometric Determination of Some FluoroquinolonesHesham SalemSimple, accurate, sensitive and selective spectrofluorimetric, atomic absorption spectrometric and spectrophotometric methods are described for the quantitative determination of ten fluoroquinolones (amifloxacin, ciprofloxacin hydrochloride, difloxacin hydrochloride, enoxacin, enrofloxacin, lomefloxacin hydrochloride, levofloxacin, norfloxacin, ofloxacin and pefloxacin mesylate). The first method was a spectrofluorimetric method in which samples of the studied drugs in 0.1 N H2SO4 showed native fluorescence at 450 nm … …American Journal of Applied Sciences, Vol. 2, Issue 3 · 31 Mar 2005 · 7,317 accessesView PDFCite
Research ArticleOpen accessIn the keywordsINHIBITORY ACTIVITY OF POTENTOX AGAINST DNA GYRASE OF ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiDNA gyrase, a type II topoisomerase catalyzes the supercoiling of relaxed closed circular DNA. In this report we evaluated the in vitro inhibitory effect of non antibiotic adjuvant compounds disodium edetate and sodium citrate against supercoiling activity of bacterial DNA gyrase. Further, we assessed the effect of different drugs alone and in combination with one or more adjuvants in overcoming … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 8 Feb 2014 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractColiforms Diversity and Antibiotic Resistance in Kazakhstan CheeseAnar Kuzeubayeva, Altay Ussenbayev, Ali Aydin et al.Coliform bacteria contaminate dairy products and pose public health concerns including food poisoning and toxemia. We aimed to determine the species diversity of coliforms and to evaluate the resistance to antibiotics of E. coli in various types of cheese sold by local producers in Kazakhstan. We collected 197 samples from different cheeses sold by producers in the Kostanay (n = … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 22 Feb 2024 · 5,993 accessesView PDFCite
Research ArticleOpen accessIn the abstractDominant Multidrug-Resistant Bacteria in Five Biggest Hospitals in Asir Region from March to June 2018Mohammed AlmaghrabiThere is a rapid increase in the emergence of multidrug resistance which consider as one of the public health threats in all over the world. MDR was defined as acquired non-susceptibility to at least one agent in three or more antimicrobial categories. The present study aims to determine the dominant multi-drug resistant bacteria in the five biggest hospitals in Asir … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 9 Mar 2021 · 6,782 accessesView PDFCite
Research ArticleOpen accessIn the abstractUTILITY OF A COMBINATION ANTIBIOGRAM FOR TREATING PSEUDOMONAS AERUGINOSALindsay Thurman, Nathan Fewel, Michael Rose, Eileen StockEmpiric combination antibiotic therapy is often used to treat severe P. aeruginosa infections. Combination antibiograms have been employed to assist clinicians in selecting the most effective two-drug antibiotic regimens. The objectives of this study were to develop a combination antibiogram in order to compare beta-lactam monotherapy versus dual-therapy with a fluoroquinolone or aminoglycoside, identify optimal combination regimens, describe the differences … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 16 Jun 2014 · 8,970 accessesView PDFCite
Research ArticleOpen accessIn the abstractCiprofloxacin Induced Chondrotoxicity and TendinopathyElias Adikwu, Nelson BrambaifaCiprofloxacin is one of the fluoroquinolones with a wide clinical acceptability. Rescently there are increasing reports on Ciprofloxacin induce Chondrotoxicity and Tendinopathy in Animal experiment and clinical experience which is of great clinical concern. A comprehensive survey and review of literaure on reported ciprofloxacin induced Chondrotoxicity and Tendinopathy in Humans and Animals was performed. It was observd that ciprofloxacin is … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 19 Oct 2012 · 10,414 accessesView PDFCite