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44 articles for “Dynamics Modeling”
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Research ArticleOpen accessPhrase in the titleUPLC-Q-Exactive Orbitrap-MS Analysis of Anchusa italica Retz. Flowers: Molecular Docking, Dynamics Modeling, and Pharmacokinetics for Cardiovascular DiseaseLinyang Wang, Yan Chen, Ainiwaer Aikemu, Shuge TianThis study builds on prior UPLC-Q-Exactive Orbit rap-MS analyses of Anchusa italica Retz. Flowers (Airfs) to explore their anti-cardiovascular mechanis·ms and key bioactive markers. UPLC-Q-Exactive Orbitrap-MS identified 30 major compounds, including polyphenols and flavonoids with strong antioxidant activity. The potential active ingredients were then screened using Lipinski's rule of five, and a network pharmacology method was employed to construct an … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Oct 2025 · 2,601 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHOMOLOGY MODELING AND MOLECULAR DYNAMICS STUDIES OF EC1 DOMAIN OF VE-CADHERIN TO ELUCIDATE DOCKING INTERACTION WITH CADHERIN-DERIVED PEPTIDEVivitri Dewi Prasasty, Usman Sumo Friend Tambunan, Teruna Jaya SiahaanVE-cadherin is a protein in the cadherin family that is found at the adherens junctions of the microvessel endothelial cells of the Blood-Brain Barrier (BBB). It is recognized as the homotypic cell adhesion molecules and there is limited structural information on how VE-cadherins mediate cell-cell adhesion. It has been shown that the EC1 domain of cadherins is important for the … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 25 Jun 2014 · 7,534 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleModeling the Dynamics of Tuberculosis Transmission in Children and AdultsF. Nyabadza, M. KgosimoreProblem statement: The fight Against Tuberculosis (TB) has mainly focused on the adult population because children were perceived to pose a very low risk in TB transmission. This assumption ignores the potential risk children had as reservoirs of latent infections from which future cases evolve when they become adults. It was therefore important to investigate the dynamics of TB taking … …Journal of Mathematics and Statistics, Vol. 8, Issue 2 · 5 Jun 2012 · 7,155 accessesView PDFCite
Review ArticleOpen accessIn the keywordsCriniviruses at the Crossroads of Virology and Agroecology: Molecular Dialogues, Vector Synchrony, and Translational Control Strategies in Crop SystemsMd. Abdullah Al Sabbir, Nabela Akter, Ankita Saha, Md. Motaher HossainCriniviruses, members of the Closteroviridae, illustrate how molecular evolution, vector ecology, and climatic variability converge to determine plant virus emergence and persistence. Although individual genomic and transmission traits are well studied, their cross-scale integration has remained limited. Recent advances in comparative genomics and high-throughput sequencing have revealed that bipartite genome reassortment, recombination hotspots, and quasi-species microdiversity provide the genetic flexibility … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 22 Sep 2026 · 476 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStructural Consequences of the Polymorphism Q223R in the Human Leptin Receptor: A Molecular Dynamics StudyJonathan P. Carrillo-Vázquez, Brenda Chimal-Vega, Beatriz Zamora-López et al.Leptin Receptor (LEPR) is a component of a signaling pathway related to appetite and energy expenditure. Single Nucleotide Polymorphisms (SNP) of Leptin receptor gene (lepr) have been proposed as possible modulator of adipose tissue and body weight. The main phenomenological consequence reported of these SNPs is the modulation of the LEP-LEPR interaction promoting the weight gain. Particularly, Q223R polymorphism has … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 3 · 23 Sep 2013 · 7,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractGait Analysis Combining Sports Biomechanics and ImagingChao ZhuAiming at the problems of marker positioning error, soft tissue interference, and insufficient personalized modeling ability in traditional gait analysis, this study proposes a gait assessment method that integrates sports biomechanics and multimodal imaging analysis. Firstly, based on the public OU-ISIR gait database, a Convolutional Neural Network (CNN) is used to extract the key gait features in the human silhouette … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 20 Jul 2026 · 858 accessesView PDFCite
Research ArticleOpen accessIn the abstractDengue Fever Prediction Empowered by Radial Basis Function Networks, Dynamic Mode Decomposition, and Learning-Based Foraging AlgorithmArchana T, Faritha Banu JDengue fever is presently considered a major health threat that must be addressed. External and internal factors that induce nonlinear oscillations in the occurrence of dengue disease have made optimal resource allocation stimulating. Public health initiatives aimed at eradicating this vector use accurate and timely data through field processes. In dengue-endemic nations, early dengue prediction remains a main concern for … …Journal of Computer Science, Vol. 22, Issue 4 · 16 Apr 2026 · 1,505 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalyzing Public Sentiment on Demonetization Using SVM: A Machine Learning ApproachKaliappan M, Guruprakash B, Rajalakshmi et al.The Indian economy experienced significant disruption following the implementation of demonetization, a policy initiative aimed at eliminating black money, controlling inflation, and promoting financial inclusion. However, this currency ban generated widespread debate and polarized public opinion. This study analyzes public sentiment toward demonetization using social media data, specifically Twitter posts characterized by mixed sentiments, sarcasm, and nuanced linguistic expressions. We … …Journal of Computer Science, Vol. 21, Issue 11 · 18 Dec 2025 · 2,247 accessesView PDFCite
Research ArticleOpen accessIn the abstractComputational Analysis of Genre Effects on Movie Ratings Using MLP AlgorithmsSubir Gupta, Upasana Adhikari, Shefali Varshney, Tanupriya ChoudhuryPredictive analytics are what the entertainment industry depends on so much in prognosticating movie ratings, which is why they inform filmmakers, distributors and stream platforms strategic moves. Traditional prediction models most times only succeed in missing out on the intricate dynamics that are genre-specific to movie ratings thereby leading to inaccuracies and suboptimal decision making. The paper proposes this research … …Journal of Computer Science, Vol. 21, Issue 4 · 19 Mar 2025 · 5,545 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Classical Design Approach of Cascaded Controllers for a Traction ElevatorUko Victor Sorochi, Kamalu Ugochukwu Anamelechi, Nwokocha Doris Adaugo, Uko Ebenezer UgochukwuA traction elevator is a control system that can be driven by Direct Current (DC) motors. Premised on the reviewed literature, operations of control systems incorporated with DC motors are restrained by nonlinearities that deviate the controlled variables (position, speed, and torque) from the reference input. Controllers designed with appropriate gains annul the nonlinearities inhibiting the operation of a traction … …American Journal of Engineering and Applied Sciences, Vol. 16, Issue 3 · 16 Aug 2023 · 6,029 accessesView PDFCite