Review ArticleOpen accessPhrase in the titleDrug Repositioning in Response to COVID-19 and other Challenging DiseasesHyellavala Joseph Fomnya, Saidu Ibrahim Ngulde, Sarah Malgwi Gana et al.Coronavirus disease is a highly contagious infection that is majorly associated with upper respiratory tract illnesses. The World Health Organization (WHO) label the novel coronavirus disease COVID-19 after an epidemic of the disease in Wuhan, Hubei province (China). Over 90 clinical trials, including drug repositioning, have been initiated to get COVID-19 treatment/management. Antibiotic resistance, drug tolerance, mutation, and adverse drug … …American Journal of Pharmacology and Toxicology, Vol. 17, Issue 1 · 28 Nov 2022 · 9,503 accessesView PDFCite
Research ArticleOpen accessIn the abstractPredicting Microbe-Drug Association based on Similarity and Semi-Supervised LearningLingzhi Zhu, Jun Wang, Guixiang Li et al.Increasing clinic evidences have showed that microbial communities play important roles in human health and disease. Predicting hidden microbe-drug associations can be helpful in understanding the microbe-drug association mechanisms in clinical treatment, drug discovery, combinations and repositioning. Some computational methods were proposed to predict the associations of microbes and drugs. However, the prediction performance of these methods needs to be … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 1 · 9 Mar 2021 · 7,535 accessesView PDFCite