92 results for “Disease Association”

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Research ArticleOpen accessPhrase in the titleRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleKRLSMDA: Identifying Human miRNA–Disease Association Based on Similarity and Kronecker Regularized Least Squares MethodLingzhi Zhu, Weimin Gao, Guixiang Li et al.A growing number of studies have suggested that miRNAs (microRNAs) have associations with human diseases, the design and discovery of drug. But so far, we do not yet fully understand the molecular mechanism of miRNAs in the development of human diseases. Predicting miRNA-disease associations is helpful for understanding the molecular mechanism of miRNAs in the development of human diseases. However, … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 1 · 15 Mar 2021 · 6,403 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titleA New Text Mining Approach for Finding Protein-to-Disease AssociationsHisham Al-Mubaid, Rajit K. SinghDiscovering significant relationships between biological entities from text documents is an important task for biologists in order to develop biological models for research and discovery, especially with the existing gigantic amounts of biomedical documents and the rate at which they are increasing everyday. We propose a new text mining method to extract associations between biological entities from text documents; and … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 3 · 30 Sep 2005 · 7,012 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleIdentification of Cancer: Mesothelioma’s Disease Using Logistic Regression and Association RuleAvishek ChoudhuryMalignant Pleural Mesothelioma (MPM) or malignant mesothelioma (MM) is an atypical, aggressive tumor that matures into cancer in the pleura, a stratum of tissue bordering the lungs. Diagnosis of MPM is difficult and it accounts for about seventy-five percent of all mesothelioma diagnosed yearly in the United States of America. Being a fatal disease, early identification of MPM is crucial … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 4 · 7 Dec 2018 · 7,224 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAssociation of Anthropometric and Metabolic Variables with Cardiovascular Disease among Urban and Rural OriginBadaruddoza, Kushal Gill, Raman KumarProblem statement: We have examined the prevalence and association of cardiovascular diseases with respect to obesity and metabolic risk factors clustering among urban and rural Punjabi males aged 20-55 years. Obesity has been defined by increased Waist Circumference (WC), Body Mass Index (BMI) and Waist Hip Ratio (WHR). Metabolic traits such as increased total cholesterol, triglycerides and lipoproteins have also … …American Journal of Applied Sciences, Vol. 8, Issue 10 · 20 Aug 2011 · 7,468 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleUtilization of Specific Index for Measuring the Association between Periodontal Conditions and Coronary Artery DiseaseNavabi Nader, Farzaneh MehdizadehProblem statement: There is increasing evidence that periodontal disease could play a role in the Progression of coronary heart disease although there are conflicting results about this association in the literature and the difference of used periodontal scoring systems among the studies might be a reason. The purpose of this study was to evaluate a specific scoring system Periodontal Index … …Current Research in Dentistry, Vol. 1, Issue 1 · 30 Jun 2010 · 8,019 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAn Unusual Association between Chromoblastomycosis and Jorge Lobo’s Disease in the Same Patient from the Amazon RegionMaurimelia M. da Costa, Silvia H. Marques da Silva, Hugo J. R. Almeida et al.A clinical case of co-infection Cladophialophora sp. and Lacazia loboi is described and in a same patient with an 18-year history of verrucous plaques and parakeloidal nodular lesions. A 50-yearold man, a laborer, living in the Anajás city, Para, Brazil (rural Amazon region), was seen at the Evandro Chagas Institute’s ambulatory. Histopathological analysis revealed intense hyperplasia and hyperkeratosis of the … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 3 · 30 Sep 2008 · 7,747 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleAssociation of DNA Polymorphism at the Apolipoprotein B-100 Gene Locus with Plasma Lipid Concentration and Coronary Artery Disease among North IndiansVivek Pratap Singh, V. Ramesh, Sonal Somvanshi et al.The aim of this study was to investigate the association between apolipoprotein B gene polymorphisms and coronary artery disease and lipid levels in north Indians. Two hundred patients of angiographically proven atherosclerotic CAD and two hundred age and sex matched control subjects were included in the study. Serum lipids including cholesterol, triglycerides, HDL, LDL, VLDL and ApoB were analyzed. PCR … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 7,892 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleThe Association of Blood Serum Atherogenicity with Risk Factors for Cardiovascular DiseaseTatiana Vladimirovna Kirichenko, Igor Alexandrovich Sobenin et al.Cardiovascular Diseases (CVD) caused by atherosclerosis are the most frequent cause of mortality worldwide, so the identification of new biomarkers of atherosclerosis development is quite actual. The atherogenicity of blood serum is considered as the potential of human serum to cause cholesterol accumulation in primary culture macrophages. The current study aimed to evaluate the association of the atherogenicity of blood … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 30 Oct 2023 · 4,917 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,073 accessesView PDF Cite