2 results for “Desferrioxamine”

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Research ArticleOpen accessEvery word in the titleDoes Iron Modulate Cytokine Production by Desferrioxamine Treated Mononuclear Cells?Hanna Bessler, Meir DjaldettiIron is an essential element for maintaining the normal function of cellular and multicellular organisms and it is closely associated with inflammation and immunity. Macrophages and lymphocytes play an important role in its homeostasis. Hereby we have evaluated cytokine production by iron depleted and iron supplemented human peripheral blood mononuclear cells (PBMC) from healthy adult donors. Non-stimulated or stimulated PBMC … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 7 Jan 2018 · 6,845 accessesView PDF Cite

Research ArticleOpen accessEvery word in the titleCombined Chelation Therapy with Deferasirox and Desferrioxamine In Removing Lead from RatsFaezeh Dahooee Balooch, Seyed Jamilaldin Fatemi, Marzieh Iranmanesh, Batool HosseinkhaniThe present study aimed to evaluate the potential efficiency of Deferasirox (DFX) and Desfferioxamine (DFO) as chelating agents in removing lead from rats as a biological model. Two different doses of lead (II) chloride (40 and 80 mg kg-1 body weight) were used for 45 days. After this period, all rats showed toxicity symptoms through loss of hair, greenish mottling … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 24 Sep 2013 · 7,151 accessesView PDF Cite