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4 articles for “De Vito Virginia”

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Research ArticleOpen accessIn the author namesNovel LC-MS/MS Method for CJ-023423 (Grapiprant) Determination in Rabbit PlasmaElena Baralla, Virginia De Vito, Maria Vittoria Varoni et al.Grapiprant is a new anti-inflammatory drug that preferentially targets the EP4 receptor of prostaglandin E2 limiting the wide range of adverse effects caused by the classical non steroideal anti-inflammatory drugs. The aim of this study was to develop and validate a new, simple, sensitive and rapid Liquid Chromatography tandem Mass Spectrometry method (LC-MS/MS) in order to quantify this novel drug … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 2 · 24 May 2018 · 7,995 accessesView PDFCite
HypothesisOpen accessIn the author namesNatural Substances as New Potential Strategies for the Treatment of Leishmaniosisin DogsDe Vito Virginia, Helen Owen, Amnart Poapolathep, Giorgi MarioLeishmaniasis is a disease caused by the protozoan parasites Leishmania, infecting numerous mammal species. Canine leishmaniasis is potentially zoonotic and causes severe fatal disease in dogs. The discovery of new natural products extracted from medicinal plants or compounds derived from them, such as quercetin, hesperidin, vitamin c, horse chestnut extract and selenium could represent a valuable source of new medicinal … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 3 · 6 Sep 2017 · 8,862 accessesView PDFCite
Research ArticleOpen accessIn the author namesBioanalytical Method Validation and Quantification of Flupirtine in Canine Plasma by HPLC with Spectrofluorimetric DetectionVirginia De Vito, Alessandro Saba, Helen Owen, Mario GiorgiFlupirtine (FLU) is a non-opioid analgesic drug belongs to the class of N-Methyl-D-Aspartate (NMDA) antagonist without antipyretic or antiphlogistic properties. No analytical method to detect FLU in canine plasma samples through a fluorimetric detector has been published to date. The analytical method described in this work provides a selective and accurate quantification of FLU. The mobile phase consisted of ACN:AcONH4 … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 22 Jun 2015 · 7,986 accessesView PDFCite
Review ArticleOpen accessIn the author namesNon-Steroidal Anti-Inflammatory Drugs in Food Producing AnimalsDe Vito VirginiaProviding adequate food supply to meet the demands of a growing population is a challenge for this century. The food producing animals bred in optimized conditions supply a large amount of food derivatives. At the same time, society has become progressively more concerned about animal suffering and aware of the need of pain prevention and treatments. One of the measures … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 12 Jun 2015 · 7,721 accessesView PDFCite