5 results for “DNA-protein structures”

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Research ArticleOpen accessIn the keywordsTolemerase Reverse Transcriptase Gene Expression as a Tumor Marker for Hepatocellular CarcinomaM. Magdi Atta, Naglaa Al-Toukhy, Omnia Al-Said et al.Problem statement: Hepatocellular carcinoma will emerge as a major form of malignancy in the coming decades. The continuing high incidence of hepatocellular carcinoma, suggests that this disease will continue to represent a global health problem far into the future. Different genes encode for the various components of the human telomerase complex. These components include the human Telomerase RNA Component (hTERC) … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 3 Aug 2011 · 7,905 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCharacterization of Mi1.2 Whitefly (Bemisia tabaci) Resistance GeneSherin Amin Mahfouze, Shipra Saxena, Heba Amin Mahfouze, Manchikatla Venkat RajamTomato (Solanum peruvianum) Mi gene provides resistance to whitefly (Bemisia tabaci), potato aphids and nematode making Mi a useful source in integrated pest management program. The aim of this work was to isolate, clone and sequence Mi1.2 gene from S. peruvianum. In addition, physico-chemical identification of amino acids deduced from Mi1.2 gene was done. Secondary (2D) and tertiary (3D) structures … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 15 Nov 2017 · 7,793 accessesView PDF Cite

Research ArticleOpen accessIn the abstractUltrastructural and Immunological Characterization of Hepatitis C Core Protein-DNA Plasmid ComplexesNelson Acosta-Rivero, Yaraima Aguilera, Viviana Falcon et al.Recently, it has been shown that a truncated HCV core (HCcAg) variant, covering the first 120 aa (HCcAg.120), interacts with plasmid DNA vaccine (pIDKE2), encoding the HCV structural proteins (HCcAg, E1 and E2). In the present work, HCcAg.120-pIDKE2 complexes, forming heterogeneous packaged structures, were visualized using a negative stain/rotary shadow technique. Interestingly, 72 hours after intramuscular injection of HCcAg.120-pIDKE2 complexes … …American Journal of Immunology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,743 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGene Technology in Tissue EngineeringXiao-Dan Sun, In-Seop LeeScaffold, cells and signaling factors are regarded as the three essential components in tissue engineering. With the development of molecular and cell biology, gene technology is beginning to show a promising position in tissue engineering as it can influence these essential components at DNA-level. By introducing plasmid DNA or genes encoding certain signaling factors (growth factors/cytokines) into the cells, required … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,401 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDF Cite