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45 articles for “Creatinine”
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Research ArticleOpen accessIn the keywordsEffects of Artemisinin-Based Combination Therapies on Lipids and Hepatorenal Circulating Indices in Guinea PigsAbaram Chesa Mankwe, Jonah Sydney Aprioku, Atuboyedia Wolfe ObianimeArtemisinin-based Combination Therapies (ACTs) are employed as first-line agents in malaria chemotherapy. In many malaria endemic areas, ACTs are frequently abused partly due to resistance, poor drug control and inadequate health facilities. This study investigated the effects of prolong administration of Artesunate-Sulfadoxine-Pyrimethamine (ATS-SP), Artesunate-Amodiaquine (ATS-Amod) and Artemether-Lumefantrine (ATM-Lum) on plasma levels of biochemical parameters (AST, ALT, ALP, urea and creatinine) … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 2 · 3 Apr 2017 · 7,282 accessesView PDFCite
Research ArticleOpen accessIn the abstractInverse Correlation Between α-Klotho and Diabetic Biomarkers in Type 2 Diabetes: A Cross-Sectional StudyYaser A.M Sulaiman, Moayad M. Al Anzy, Omeed Akbar Ali, Adnan M. IsmailEvidence suggests a link between diabetes and Klotho protein, demonstrated by reduced Klotho gene expression in individuals with diabetes, α- klotho the potential modulator of kidney health in DM. Klotho is primarily expressed in the kidneys and has an anti-inflammatory and antioxidant role, which may protect against the pathological processes that damage renal function in diabetes. Research conducted in Japan … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 837 accessesView PDFCite
Case ReportOpen accessIn the abstractAlcohol-Induced Rhabdomyolysis Complicated by Hyponatremia and Acute Kidney Injury Following Minor Trauma: A Case ReportVinay Tulsian, Drupad Das, M Sukumar, Prasan Kumar PandaRhabdomyolysis from alcohol is established, but combined binge intake, minor trauma, and vomiting-induced hyponatremia is a complex clinical scenario. Case study: This case report describes a young male with a three-year history of alcohol consumption who presented with rhabdomyolysis following binge drinking and a mild traumatic fall. He experienced 10 to 15 episodes of vomiting post-alcohol intake, subsequently developing anasarca. … …American Journal of Pharmacology and Toxicology, Vol. 20, Issue 1 · 23 May 2026 · 1,700 accessesView PDFCite
Case ReportOpen accessIn the abstractSurvival Following Severe Paraquat Poisoning a Case Study from the Andaman and Nicobar IslandsShiv Shankar Singh, Colin Sanchez, Prasan Kumar PandaParaquat poisoning continues to pose a significant public health challenge in the Andaman and Nicobar Islands, largely due to its alarmingly high mortality rate. In this report, we present the case of a 39-year-old male farmer who ingested 30 mL of paraquat with the intent of suicide. Initially, the patient underwent prompt gastric lavage and exhibited relative stability. Upon admission, … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 22 Jan 2025 · 10,605 accessesView PDFCite
Literature ReviewOpen accessIn the abstractLiterature Study on Factors Influencing the Biochemical Analytes Stability in Blood, Serum and Plasma: Systematic ReviewSamia El Mahi, Asmae Tantane, Sanaa Ait Hamou, Said OubraimBlood testing represents an essential phase in diagnosis and treatment. It is important to comprehend the biochemical analytes' stability. This research gathers information from different journals that have investigated the stability of biochemical analytes under different conditions. This research aims to collect and analyze data about conditions that promote stability, conditions that lead to instability, and how stability varies in … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 3 · 21 Aug 2024 · 5,192 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepato and Nephrotoxicity Caused by Sub-Chronic Exposure to Relevant Concentrations of Human Exposure to Glyphosate-Based Herbicide: An Experimental Study in RatsFernanda de Maria Serra, Letícia Rocha Magalhães, Beatriz Bertholace Magalhães Silva et al.Glyphosate's remarkable effectiveness in weed control has made it among the foremost widely employed herbicides globally. Several Glyphosate-Based Herbicides (GBHs) contain 1-4 dioxane, a compound known to induce cancer in animals and potentially contribute to liver and kidney damage in humans. The objective was to assess the liver and kidney toxicity resulting from sub-chronic exposure to GBH in rats. Eighty … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 26 Dec 2023 · 5,194 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of B-Glucan Against Ehrlich Ascites Carcinoma Induced Renal Toxicity in MiceAhmed Flayyih Hasan, Azhar Azher Alankooshi et al.Several studies have been focused on identifying alternative medicines for the treatment of cancer. This study aimed to investigate the impact of B-Glucans extract (BG) against Ehrlich Ascites Carcinoma (EAC) induced toxicity and tissue damage in kidney. A total of 40 mice were assigned randomly to four groups (G1, control; G2, B-Glucans (75 mg/kg bw/day) orally for 2 weeks; G3, … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 23 Feb 2023 · 5,592 accessesView PDFCite
Research ArticleOpen accessIn the abstractOrlistat Induce Renal Toxicity, DNA Damage, and Apoptosis in Normal and Obese Female RatsHaneen Mushtaq Hameed, Ahmed Flayyih Hasan, Zainab Haytham Razooki et al.Obesity has been linked to several chronic diseases, including fatty liver disease, fatty heart disease, diabetes mellitus, hypertension, obstructive sleep apnea, and cancer. The purpose of the current study was to determine how Orlistat affected renal toxicity, DNA damage, and apoptosis that were brought on by obesity in normal and obese female rats. There were four groups made up of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 18 Jan 2023 · 5,831 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Lactoferrin against Chromium Induced Adverse Renal Changes in Rats: Oxidative Stress TheoryMohammed H. Hassan, Dorreia Abd-Alla Mohamed Zaghloul, Marwa Ahmed Mahmoud et al.Among the toxic metals, chromium (Cr) which is a naturally occurring heavy metal commonly enters the environment through the effluents from various industries. Kidney disease is often cited as an adverse effect of chromium. We aimed to assess chromium-induced pathophysiological adverse renal damage and determine the potential protective effects of co-therapy with Lactoferrin (LF) in male albino rats. Forty male … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 28 Apr 2021 · 6,663 accessesView PDFCite
Literature ReviewOpen accessIn the abstractCystatin C as a New Biomarker in Patients with Chronic Kidney Disease a Review and Meta-AnalysisLingxin Bao, Qiaoyan Zhou, Yanfang Lin et al.The objective of this study was to evaluate the correlation between cystatin C (CysC) and patients with Chronic Kidney Disease (CKD). Prospective or retrospective cohort studies which compared the levels of CysC in patients with CKD and healthy controls were searched on PubMed, Contents, CINAHL and EMBASE from 2013 to December 31, 2020. R3.5.2 software was utilized to perform data … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 12 Oct 2021 · 6,568 accessesView PDFCite