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32 articles for “Combination Therapy”
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Literature ReviewOpen accessEvery word in the titleMycobacterium Abscessus Native Tricuspid Valve Endocarditis. Is a Six-Week Course of Combination Antibiotic Therapy Enough?Rabindra Ghimire, Dora Lebron, William Matthew Wooten et al.A 24-year-old Caucasian woman with a history of intravenous drug abuse and multiple hospital admissions for substance abuse related medical problems presented with pneumonia and was discharged home on oral antibiotics. Three days later, her blood culture grew acid fast bacilli, which was subsequently identified as M. abscessus subspecies abscessus. Transthoracic and transesophageal echocardiogram (TTE and TEE respectively) was suggestive … …American Journal of Infectious Diseases, Vol. 16, Issue 1 · 20 Feb 2020 · 7,281 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUTILITY OF A COMBINATION ANTIBIOGRAM FOR TREATING PSEUDOMONAS AERUGINOSALindsay Thurman, Nathan Fewel, Michael Rose, Eileen StockEmpiric combination antibiotic therapy is often used to treat severe P. aeruginosa infections. Combination antibiograms have been employed to assist clinicians in selecting the most effective two-drug antibiotic regimens. The objectives of this study were to develop a combination antibiogram in order to compare beta-lactam monotherapy versus dual-therapy with a fluoroquinolone or aminoglycoside, identify optimal combination regimens, describe the differences … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 16 Jun 2014 · 8,970 accessesView PDFCite
Research ArticleOpen accessIn the keywordsNEWER DRUGS FOR VISCERAL LEISHMANIASIS: A REVIEWKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Visceral Leishmaniasis (VL) is one of the most neglected tropical diseases worldwide. The diagnosis and treatment of this disease is quite complex. Sodium Antimony Gluconate (SAG) which used to be a very effective treatment has now developed resistance and is potentially a cardio-toxic drug. Pentamidine has now been discarded because of adverse effect of diabetes mellitus. Amphotericin-B is an effective … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 5 May 2014 · 7,133 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAn Overview of Malaria ControlEmmanuel Chanda, Mulakwa Kamuliwo, Richard W. Steketee et al.Malaria remains a serious global public health problem and a leading cause of morbidity and mortality in sub Saharan Africa. In Zambia the disease is endemic with stable transmission, accounting for 40% of all out-patient attendances and is responsible for 20% deaths among children under five. Scaling up of scientifically proven high impact preventive, curative and supportive interventions and deploying … …Current Research in Medicine, Vol. 4, Issue 1 · 29 Apr 2013 · 7,960 accessesView PDFCite
Research ArticleOpen accessIn the abstractRapid Recovery of Peripheral Oxygen Saturation in Hypoxic COVID-19 Patients With Ivermectin/Doxycycline/Zinc Multidrug TherapySabine Hazan, Adriana C. Vidal, Eleftherios Gkioulekas et al.Several combination therapies for the early outpatient treatment of COVID-19 were proposed by independent research groups at the onset of the pandemic during 2020 and 2021. In this observational study, we report on the outcomes of an off-label triple combination therapy, consisting of ivermectin, doxycycline, and zinc, with adjunct vitamin C and D3 supplementation, which was used on high-risk COVID-19 … …American Journal of Infectious Diseases, Vol. 22, Issue 1 · 3 Jul 2026 · 3,374 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of an IgY-Based Immunomodulatory Combo on the Internalization of Staphylococcus aureus by HC11 Cells: Preliminary in vitro Studies IIZarete Jatna Isha, Adu-Addai BenjaminInfectious mastitis is a common disease of cattle of economic significance. Clinical mastitis affects between 20 to 25% of dairy cows each year. Staphylococcus aureus (SA) causes an estimated 10-11.7% of bovine infectious mastitis cases in the US, reducing milk production, increasing morbidity, increasing antibiotic use and milk waste, and fueling premature culling. The SA mastitis cure rate varies from … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 1 Feb 2026 · 2,814 accessesView PDFCite
Review ArticleOpen accessIn the abstractGabapentin in Cattle: A Pharmacology SnapshotCharbel Fadel, Irene Sartini, Mario GiorgiGabapentin (GBP) is an antiepileptic and analgesic drug that is derived from gamma-aminobutyric acid. It is used as an analgesic in multi-modal pain management, as well as an anticonvulsant and anxiolytic, off-label in animals. Particularly, oral GBP prescriptions for cattle are becoming increasingly popular. Since its introduction into cattle farm practices, several types of research on GBP in cattle have … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 3 · 29 Jul 2022 · 7,821 accessesView PDFCite
EditorialOpen accessIn the abstractEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,657 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite