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10 results for “Cocaine”
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Research ArticleOpen accessEvery word in the titleCocaine Exposure Results in Formation of Dendritic Varicosity in Rat Primary Hippocampal NeuronsHonghong Yao, Crystal Bethel-Brown, Anil Kumar, Shilpa BuchProblem statement: It has been well documented that drugs of abuse such as cocaine can cause enhanced progression of HIV-Associated Neuropathological Disorders (HAND), the underlying mechanisms mediating these effects remain poorly understood. Approach: In present study, we explored the impact of cocaine exposure (I and 10 μM) on the dendritic beading in rat primary hippocampal neurons. Using the approach of … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 7,889 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCocaine: A Catalyst for Human Immunodeficiency Virus-Associated DementiaNavneet K. Dhillon, Milind Gadgil, Andy Rahardja et al.Injection drug use has been recognized as a major risk factor for AIDS from the outset of the epidemic. Cocaine, one of the most widely abused drugs in the United States can both impair the functions of macrophages and CD4+ lymphocytes and also activate HIV-1 expression in these cells. Cocaine is a multifactorial agent that acts globally to impair the … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,587 accessesView PDFCite
CorrigendumOpen accessEvery word in the titleCorrigendum: Cocaine Exposure Results in Formation of Dendritic Varicosity in Rat Primary Hippocampal NeuronsHonghong Yao, Crystal Bethel-Brown, Shilpa BuchCorrection to: American Journal of Infectious Diseases http://doi.org/10.3844/ajidsp.2009.26.30, published online 2009; updated 08 February 2021 The authors have recently noticed that the representative image of MAP2 immunostaining in the control group in Figure 3A was incorrectly chosen. This error was inadvertently caused during the assembly of the images due to our negligence in the process of reformatting our manuscript. Original … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 8 Feb 2021 · 6,416 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBorderline Personality Symptoms and Human Immunodeficiency Virus Risk in Alcohol and Other Drug Abusing Adolescent OffendersJessy G. Dévieux, Robert M. Malow, Rhonda Rosenberg et al.Problem statement: Incarcerated youth with borderline symptomatology represent a particularly at risk-population due to their enggement in risky behaviors. Five hundred twenty two adolescents were assessed for borderline symptomatology (MACI), engagement in risky behaviors and attitudes/knowledge. Approach:Adolescents were divided into two groups: low borderline (below the 60 scale score cutoff) and high borderline (subclinical and clinical range). Multivariate analyses were … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 7,814 accessesView PDFCite
Case ReportOpen accessIn the abstractMystifying Toxidrome: A Case of Heroin Body Packer SyndromePrasan Kumar Panda, Tom Jose Kakkanattu, Arvind Kumar et al.Drug trafficking is an international problem. Over years it has increased in prevalence and concealment methods. Body packers swallow wrapped packets of illicit drugs, mainly cocaine and heroin and try to conceal them from security personnel. They present to physicians either as body packer syndrome with symptoms of intoxication or asymptomatically on suspicion of drug concealment, for observation. We report … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 2 · 18 Jun 2016 · 7,731 accessesView PDFCite
Research ArticleOpen accessIn the abstractObservations on the Relationship between Opioid Medications, Illicit Drugs and Heroin Use in Pain PatientsDavid AlanYee, Michelle Marie Hughes, Rabia Samady Atayee et al.Problem statement: Patients on chronic opioid therapy are monitored to detect illicit drug use in order to deter diversion of their prescription opioids and to ensure medication adherence. The addictive potential of opioid drugs and their similar binding sites in the brain may make them potential gateway drugs for each other. Recent reports indicate that oxycodone has a high probability … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 7 Jun 2011 · 7,957 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Path to Treatment: Does It Matter? Relapse and the Reason for Seeking TreatmentEvelyn A. Cage, Annette S. KluckProblem statement: Substance abuse is difficult to treat and many of those who struggle with substance abuse do not see treatment as necessary. Moreover, relapse is common among those who receive treatment. Family and friends of Individuals With Addictions (IWAs) sometimes use ultimatums to encourage the IWA to enter treatment. What is less clear is whether IWAs are more likely … …Current Research in Psychology, Vol. 1, Issue 1 · 30 Jun 2010 · 7,635 accessesView PDFCite
Research ArticleOpen accessIn the abstractCoronary Heart Disease (CHD) Risk Factors and Metabolic Syndrome in HIV-Positive Drug Users in MiamiMarianna K Baum, Carlin Rafie, Shenghan Lai et al.The frequency of coronary heart disease (CHD) is increasing among HIV seropositive persons. This phenomenon may be related to HIV disease itself, the use of antiretroviral medications and increased length of survival, or the synergism of these factors. In this study we have calculated the 10-year CHD risk estimate and the prevalence of metabolic syndrome in a cohort of 118 … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,989 accessesView PDFCite
Research ArticleOpen accessIn the abstractGonadal and Adrenal Abnormalities in Drug Users: Cause or Consequence of Drug Use Behavior and Poor Health OutcomesTodd T. Brown, Amy B. Wisniewski, Adrian S. DobsOpiates and cocaine both have effects on adrenal and gonadal function. Opiates suppress the hypothalamic-pituitary adrenal (HPA) axis, whereas cocaine leads to HPA activation. Opiates also cause gonadal dysfunction in both men and women. During withdrawal from opiates and cocaine, the HPA axis is activated which may reinforce relapse behavior. This review describes these hormonal effects and explores the potential … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 7,049 accessesView PDFCite
Research ArticleOpen accessIn the abstractFactors Associated with Syringe Sharing Among Users of a Medically Supervised Safer Injecting FacilityEvan Wood, Mark W. Tyndall, Jo-Anne Stoltz et al.Vancouver, Canada recently opened a medically supervised safer injecting facility (SIF) in an effort to reduce HIV and overdose risk and public injection drug use. We sought to examine factors associated with syringe sharing among SIF users. SIF users were randomly recruited into a prospective cohort of SIF users known as the Scientific Evaluation of Supervised Injecting (SEOSI) cohort. We … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 10,759 accessesView PDFCite