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Research ArticleOpen accessIn the keywordsExogenous Pyocyanin Alters Pseudomonas aeruginosa Susceptibility to CiprofloxacinGary D. Grant, Tian Tian Zhang, Lee S. Gloyne et al.This in vitro cell-based study identified the contributing role of pyocyanin in the resistance of Pseudomonas aeruginosa to ciprofloxacin. Problem statement: P. aeruginosa is the major pathogen in the Cystic Fibrosis (CF) lung with pyocyanin being a critical component of its virulence. Prevalence is high and, once acquired, chronic infection is difficult to eliminate. Ciprofloxacin remains a crucial oral agent … …Current Research in Microbiology, Vol. 1, Issue 1 · 30 Jun 2010 · 8,792 accessesView PDFCite