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9 results for “Central pain”

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Research ArticleOpen accessPhrase in the titleAn Induced Hematoma in Caudoputamen Nuclei in Rats Causes Central Pain when the Thalamus is also Implicated and the Central Sensitization is Reversed with GabapentinP. P. Lema, P. VachonProblem statement: The objective of this study was to evaluate pain sensitisation in rats following the induction of an intracerebral hemorrhage by injecting a collagenase solution in the caudoputamen nucleus of the right basal ganglia and to evaluate gabapentin as an analgesic for central pain. Approach: Thirty male Sprague-Dawley rats weighing between 175-300 g were used. In a first experiment, … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 10 Mar 2012 · 8,167 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplying Neural Network-Based Approach to Sickle Cell Disease-Related Pain ClassificationZacchaeus Omogbadegun, Israel Ogundele, Olufunke OladipupoSickle Cell Disease (SCD), an inherited Red Blood Cell (RBC) disorder, is characterized by anaemia, end-organ damage, unpredictable episodes of pain and early mortality. SCD affects 25% of people living in Central and West Africa causing life threatening “silent” strokes and lifelong damage. Nigeria accounts for 50% of SCD births worldwide (estimated 150,000 of 300,000 babies born with Symptomatic Sickle … …Journal of Computer Science, Vol. 15, Issue 6 · 28 Jun 2019 · 7,678 accessesView PDFCite
EditorialOpen accessIn the abstractVisceral Pain: Basic Research Concepts and Therapeutic InterventionsVictor V. ChabanThe accumulation of nociceptive diseases that limit normal body functions is a major risk factor for a disability, and visceral pain is one of the most prevalent human health problems. Additionally, many pain-associated diseases are accompanied by the concomitant decline in cognitive and motor performance. The complex interplay and balance between diverse signal transduction mediators, genetic background and environmental factors … …International Journal of Research in Nursing, Vol. 6, Issue 2 · 26 Aug 2015 · 7,148 accessesView PDFCite
Review ArticleOpen accessIn the abstractTransient Receptor Potential Vanilloid 1 Involvement in Animal Pain PerceptionCristina Vercelli, R. Barbero, G. ReIn last decades, Transient Receptor Potential Vanilloid 1 (TRPV1) has been the target of a large number of scientific investigations. It has been identified as a polymodal transducer molecule on a sub-set of primary sensory neurons which responds to various endogenous and exogenous stimuli including noxious heat (more than 42°C), protons and vanilloids such as capsaicin, the hot ingredient of … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 1 · 30 Mar 2015 · 7,266 accessesView PDFCite
Research ArticleOpen accessIn the abstractDETECTION OF MYCOPLASMA HOMINIS IN PATIENTS WITH URINARY TRACT INFECTIONSOsama M.S. Abdul-Wahab, Mishari H. Al-Shyarba, Mohammed M. AssiryMycoplasma hominis is one of the well known genital mycoplasma agent that has been recognized as potentially pathogenic species and associated with various infectious diseases in adult men and woman. The organism could cause pelvic inflammatory disease, postpartum, postabortion fever and pyelonephritis. The Aim of this prospective study was to detemine the occurrence and prevalence of Mycoplasma hominis in patients … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 14 May 2014 · 8,283 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Gc-Macrophage Activating Factor in Human Neurons; Implications for Treatment of Chronic Fatigue SyndromeRodney Smith, Lynda Thyer, Emma Ward et al.Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disease of multifactorial aetiology characterized by immune system dysfunction, widespread inflammation, multisystemic neuropathology and persistent pain. Given the central role of the immune system in the pathogenesis of the syndrome, we studied the effects of a potent modulator of the immune system in in vitro and in vivo models that could help … …American Journal of Immunology, Vol. 9, Issue 4 · 6 Nov 2013 · 10,982 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalgesic and Antioxidant Activity of the Hydromethanolic Extract of Mikania scandens (L.) Willd. LeavesS.M. Raquibul Hasan, Mariam Jamila, Muntasir Mamun Majumder et al.Problem statement: Mikania scandens (L.) Willd., a medicinal plant, is popularly used as herbal remedy for various ailments in Bangladesh. But the scientific basis for its medicinal use especially in pain and inflammation remains unknown. Therefore, the present study was designed to evaluate analgesic and antioxidant potential of the hydromethanol extract of the leaves of the plant. Approach: The analgesic … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 1 · 31 Mar 2009 · 12,542 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe European Miracle Psychological Stages and the Origin of Modern SocietyGeorg Oesterdiekhoff, Jörn Rüsen, Hans-Jürgen HummellThe idea that the rise of modern, industrial society originates in psychological advancements is to find among classic authors of sociology and history such as Comte, Elias and Lamprecht and more recently described by Habermas. It will be shown that central transformations within sciences, industrial economy, political structures, Enlightenment, humanitarian revolution, law, painting, music and literature having taken place during … …Journal of Social Sciences, Vol. 16, Issue 1 · 15 May 2020 · 7,672 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordThe Antinociceptive Effects of Central and Peripheral Administration of Peganum harmala L. Extracts in Animal ModelsRachida Aboufatima, Loubna Farouk, Mehdi Ait Laaradia et al.The medicinal plant Peganum harmala has been used in traditional Moroccan medicine to accelerate the healing process of various diseases and to relieve the pain. The antinociceptive effect of the Aqueous (AE), Dichloromethane (DE) and Butanolic (BE) extracts of the Peganum harmala L. was tested in mice and rats by chemical and thermal models. Plant seed extracts were given intraperitoneally … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 29 May 2021 · 6,423 accessesView PDFCite