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89 articles for “Biomarker”
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Research ArticleOpen accessEvery word in the titleDetection of Cancer Biomarkers with NanotechnologyLei Zhang, Dan Lv, Weijun Su et al.Early detection of cancer biomarkers with high precision is critically important for cancer therapy. A variety of sensors based on different nanostructured materials have attracted intensive research interest due to their potential for highly sensitive and selective detection of cancer biomarkers. This review covers the use of a variety of nanostructured materials, including carbon nanotubes, silicon nanowires, gold nanoparticles and … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 8,280 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiomarker Quantitation: Analytical Considerations for Ligand Binding Assay Regression Curves and Quality Control SamplesMark DysingerAs biomarkers grow in relevance for both the design and support of therapeutics and the clinical trials associated with them, there is an ever increasing need for accurate quantitation of these biochemical entities in biological matrices. While quantifying many biotherapeutics via ligand binding assay platforms can be fairly straightforward, biomarkers present some unique challenges that must be taken into account … …American Journal of Immunology, Vol. 8, Issue 3 · 25 Aug 2012 · 8,028 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRole of Progranulin Gene Expression as a Molecular Biomarker for Bladder CancerSalwa M. Abo El-khair, Mie A. Mohamed, Tamer E. AlkhiaryBladder cancer is the second most common cancer of the urinary system. Early diagnosis of this tumor and estimation of risk of future progression has a significant impact on prognosis. Although there are several molecular markers for the diagnosis and prognosis for this tumor, their accuracy is not ideal. Progranulin is a growth factor that may play a critical role … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 7,699 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleEndometriosis-Search for BiomarkersKralickova Milena, Vetvicka VaclavNumerous studies are seeking noninvasive methods to diagnose endometriosis, but a clinically applicable test is still missing. Current paper compares the current results in our search for the best diagnostic marker. We summarize that despite the extensive research on endometriosis biomarkers, timely diagnosis using specific biomarkers remains an unfilled dream. …American Journal of Immunology, Vol. 12, Issue 2 · 29 Jul 2016 · 6,847 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNovel Biomarkers in Determining Prostate Cancer Diagnosis and PrognosisZuzana Varchulova Novakova, Katarina Bevizova, Iveta GasparovaThe clinical behavior and molecular pathology of prostate cancer is highly variable. Current "traditional" prognostic markers cannot reliably distinguish the potentially life-threatening cancer from indolent cancer. Identification of additional new predictors of cancer aggressiveness is therefore urgently required. This communication is aimed at a brief review of new biomarkers in prostate cancer diagnostics and prognostics. Pubmed systematic search was performed … …OnLine Journal of Biological Sciences, Vol. 14, Issue 4 · 14 Jan 2015 · 6,903 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMountain Sheep: An Environmental Epidemiological Survey of Variation in Metal Exposure and Physiological Biomarkers Following Mine DevelopmentLawrence K. Duffy, Michael W. Oehler, R. Terry Bowyer, Vernon C. BleichProblem Statement: Anthropogenic activities, such as mining and industrial operations, are a major environmental source of metal exposure for wildlife. Quantitative data regarding biochemical effects of exposure to mineral extraction on mountain sheep, Ovis canadensis, are limited, although their habitats are becoming increasingly affected by expanded resource development. Decisions relating to environmental protection and wildlife conservation should be based on … …American Journal of Environmental Sciences, Vol. 5, Issue 3 · 30 Jun 2009 · 6,654 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Proteomics Analysis of Drought Stress-Responsive Proteins as Biomarker for Drought-Tolerant Sugarcane CultivarsNisachon Jangpromma, Supansa Kitthaisong, Khomsorn Lomthaisong et al.Problem statement: The prime objective in breeding selection process of drought-tolerant sugarcane is to identify the correlating marker, which could lead to rapid screening for drought-tolerant cultivars. In this study, we have reported an unknown 18-kDa protein (p18) along with other stress-inducible proteins to be highly expressed in sugarcane leaves under drought stress condition. Approach: The 2D-PAGE patterns of proteins … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 9,814 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDiagnostic Potential of Inflammatory Biomarker Levels in the Serum of Patients with Hepatitis B Infection: A Retrospective StudyHyeokjun Yun, Bo Kyeung Jung, In Soo Rheem et al.This study aimed to evaluate the diagnostic biomarker potential of C-Reactive Protein (CRP) and Procalcitonin (PCT) levels in the serum of individuals infected with the Hepatitis B Virus (HBV). The patients were divided into two age groups: Younger (<60 years) and older (≥60 years). An Electrochemiluminescence Immunoassay (ECLIA) platform was employed for the serological analysis to quantify the biomarker levels. … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 10 Aug 2023 · 5,270 accessesView PDFCite
Literature ReviewOpen accessEvery word in the titleCystatin C as a New Biomarker in Patients with Chronic Kidney Disease a Review and Meta-AnalysisLingxin Bao, Qiaoyan Zhou, Yanfang Lin et al.The objective of this study was to evaluate the correlation between cystatin C (CysC) and patients with Chronic Kidney Disease (CKD). Prospective or retrospective cohort studies which compared the levels of CysC in patients with CKD and healthy controls were searched on PubMed, Contents, CINAHL and EMBASE from 2013 to December 31, 2020. R3.5.2 software was utilized to perform data … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 12 Oct 2021 · 6,568 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Construction of Two and Three Dimensional Molecular Models for the miR-31 and Its Silencer as the Triple Negative Breast Cancer BiomarkersArli Aditya ParikesitThe Triple Negative Breast Cancer (TNBC) is considered as the most difficult Breast Cancer type to be medicated. So far, the acceptable medication and diagnostics measure are based upon the proteomics-world view, especially with utilizing the natural products and their derivatives as drug candidates. However, as the transcriptomics-studies are getting more advanced, the research on non-coding (nc)RNA is being considered … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 18 Oct 2018 · 7,772 accessesView PDFCite