Detection of Cancer Biomarkers with Nanotechnology
Lei Zhang1, Dan Lv2, Weijun Su1, Yanhua Liu1, Yanan Chen1 & Rong Xiang1 Show affiliations
- Nankai University, China
- University of California, United States
American Journal of Biochemistry and Biotechnology, Volume 9, Issue 1, pp. 71–89 · doi.org/10.3844/ajbbsp.2013.71.89
Abstract
Early detection of cancer biomarkers with high precision is critically important for cancer therapy. A variety of sensors based on different nanostructured materials have attracted intensive research interest due to their potential for highly sensitive and selective detection of cancer biomarkers. This review covers the use of a variety of nanostructured materials, including carbon nanotubes, silicon nanowires, gold nanoparticles and quantum dots, in the fabrication of sensors. Emphases are placed on how the detection systems work and what detection limits can be achieved. Some assays described in this review outperform established methods for cancer biomarker detection. It is highly promising that these sensors would soon move into commercial-scale production and find routine use in hospitals.
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Zhang, L., Lv, D., Su, W., Liu, Y., Chen, Y. & Xiang, R. (2013). Detection of Cancer Biomarkers with Nanotechnology. American Journal of Biochemistry and Biotechnology, 9(1), 71–89. https://doi.org/10.3844/ajbbsp.2013.71.89
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