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3 results for “Atorvastatin”

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Research ArticleOpen accessEvery word in the titleEffects of Atorvastatin on Oxidized Low-Density Lipoprotein-induced Proliferation, Apoptosis, and Matrix Metalloproteinase-9 Expression in Human MacrophagesBensheng Liu, Huifan Li, Yan Wang, Li ZhangAtorvastatin (ATV), an HMG-CoA reductase inhibitor, is utilized in the treatment of atherosclerotic diseases. Mononuclear Macrophages (MMs) are critical immune cells involved in atherosclerosis progression, participating in processes such as foam cell formation, cytokine secretion, and the development of fibrous cap and lipid core. To further elucidate the mechanism by which ATV exerts its therapeutic effects on atherosclerosis through the … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 18 Nov 2025 · 2,133 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSimultaneous Determination of Amlodipine and Atorvastatin in Caduet® Tablets Using HPLCMaha Abdalla AlnowaiserA simple, selective, sensitive and precise, simultaneous high performance liquid chromatographic analysis of tablets containing amlodipine and atorvastatin was described. Good chromatographic separation was achieved using a Perfectsilr Target ODS-3 (4.6 cm × 250 mm, 5 µm) and a mobile phase consisting of acetonitrile-phosphate buffer pH 4.5 (55:45, v/v) at a flow rate 1ML min-1. The ultraviolet detector was set … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 7,091 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStatin Therapy in the Management of Diabetes Mellitus; How Relevant?Fasanmade Olufemi Adetola, Odeniyi Ifedayo AdeolaDiabetes is associated with the development of premature cardiovascular disease. There have been many clinical trials of statin treatment conducted in patients with Coronary Heart Disease (CHD). Taking a closer look at the subset of those patients with diabetes mellitus puts no doubt on the beneficial effect of lowering cholesterol with statin in these patients. Earlier studies done dwell more … …Current Research in Medicine, Vol. 4, Issue 1 · 25 Mar 2013 · 7,868 accessesView PDFCite