5 results for “Amyloid Beta”

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Research ArticleOpen accessEvery word in the titleAnalysis of Plasma Amyloid-Beta and Apolipoprotein E Genotypes as Markers of Alzheimer’s Disease in Healthy Korean AdultsEun Ju Oh, Jung Jae Lee, Bo Kyeung Jung, Jae Kyung KimThe presence of the ApoE4 allele interferes with human Amyloid-Beta (Aβ) clearance and reduces the neuronal damage response, which, in turn, is associated with increased Alzheimer’s Disease (AD) risk. Identifying individuals with the highest genetic risk may aid clinical AD diagnosis and prognosis. However, to the best of our knowledge, no previous study has performed blood-based analysis of ApoE polymorphisms … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 26 Mar 2024 · 4,492 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsA Review of Biochemical Markers for Early Diagnosis of Alzheimer’s DiseaseMeha Fatima Aftab, Rizwana S. WaraichAlzheimer’s disease, the most prevalent type of dementia, affects the life of elderly, to such extent that it impairs the ability to perform routine functions as well. The impairment of normal functions not only affects the patients but the family members as well. It is difficult to make a definitive diagnosis; hence some clinical and psychological tools are used to … …Neuroscience International, Vol. 3, Issue 2 · 4 Sep 2012 · 13,511 accessesView PDF Cite

Literature ReviewOpen accessIn the keywordsAtherosclerosis and Alzheimer’s Disease Interconnection: Inflammation, Aβ and MoreAnastasia Vladimirovna Poznyak, Victoria Khotina, Roghayyeh Vakili-Ghartavol et al.Despite being the leading cause of CVD and cardiovascular mortality globally, Atherosclerosis (ATH) remains underdiagnosed and undertreated. The reasons behind Alzheimer’s Disease (AD) also remain unclear and there is currently no cure for it. At present, at least 55 million people are believed to be suffering from the disorder and the figures are expected to grow. At the same time, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 26 May 2024 · 4,761 accessesView PDF Cite

Research ArticleOpen accessIn the abstractButyrate-Mediated Genomic Changes Involved in Non-Specific Host Defenses, Matrix Remodeling and the Immune Response in the Rumen Epithelium of Cows Afflicted with Subacute Ruminal AcidosisLouis Dionissopoulos, Anne Hermen Laarman, Ousama AlZahal et al.Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by butyrate have not been defined. The objective of this study was to define the inflammatory-related genomic changes … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 10 Jan 2013 · 8,059 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA New Text Mining Approach for Finding Protein-to-Disease AssociationsHisham Al-Mubaid, Rajit K. SinghDiscovering significant relationships between biological entities from text documents is an important task for biologists in order to develop biological models for research and discovery, especially with the existing gigantic amounts of biomedical documents and the rate at which they are increasing everyday. We propose a new text mining method to extract associations between biological entities from text documents; and … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 3 · 30 Sep 2005 · 7,012 accessesView PDF Cite