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Research ArticleOpen accessIn the keywordsDesign, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular AgentsMehul M. Patel, Mahesh T. ChhabriyaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Although many active antitubercular agents have since been developed, drug resistance will continue to be a problem. Therefore, there is a clear … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,430 accessesView PDFCite