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76 articles for “2A Peptide”
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Research ArticleOpen accessEvery word in the titleInfluence of Sturgeon Protein Fractions on Active Peptide Generation via Enzymatic HydrolysisMengjie Lu, Yingmei Hou, Yejing Sun et al.To identify the sturgeon protein component responsible for generating bioactive peptides, including antioxidant peptides and alcohol dehydrogenase (ADH) promoting peptides, sturgeon protein and its isolated protein components (sarcoplasmic, myofibrillar, and stromal proteins) were studied. Among the four isolated protein components, stromal protein demonstrated the highest susceptibility to enzymatic hydrolysis (P<0.05). Besides, pepsin and alkaline protease are the most effective enzymes … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 8 Apr 2026 · 1,419 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePredicting Antigenic Peptides Using a Multi-Level Transformer Model with Enhanced Feature SelectionAshwini S., Minu R. I., Jeevan KumarThis Antigenic Peptide (APs) prediction is one of the most important roles to improve vaccine design and interpret immune responses. This paper develops a Multi-Level Pooling-based Transformer model, which improves the accuracy and efficiency of predicting T-cell epitopes. The model utilizes peptide sequences from the Immune Epitope Database, employing a refined Kolaskar and Tongaonkar algorithm for feature extraction and a … …Journal of Computer Science, Vol. 21, Issue 7 · 17 Jul 2025 · 3,443 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntioxidizing Efficiency of Yogurt Probiotics Peptides Concerning Egg Yolk NutrientsSyifa Silviarahma Nurfadilah, Lovita Adriani, Deny Saefulhadjar et al.Yogurt contains bioactive peptides that serve as antioxidants. These peptides can inhibit the production of free radicals in laying chicken body cells, affecting egg quality. We aimed to evaluate the impact of the antioxidant potential of Water-Soluble Peptide Extract (WSPE) yogurt on the protein, lipid, and cholesterol levels in yolks from chicken eggs. We used a completely randomized design (CRD) … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 1 · 31 Jan 2025 · 6,235 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInvestigation of the Contribution of Late Embryogenesis Abundant (LEA) K Peptide in Enhancing the Expression of Lipase from Sphingobacterium sp.: In vitro and in Silico StudiesIbrahim Muhammad et al.Sphingobacterium sp. AB3 lipase is a psychrophilic enzyme with optimal lipolytic activity at pH 7 and 15°C. The cold-adapted properties of the lipase render it suitable for various low-temperature industrial applications such as biodiesel production, detergent formulation, and non-thermal food processing. Recent studies have shown that co-expression of LEA K peptide with AB3 lipase resulted in enhanced protein expression in … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 21 Nov 2024 · 4,569 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleVirtual Screening of CPP Conjugated Peptide as QcrB BCC Protein Inhibitors of Mycobacterium tuberculosis BacteriaMuhammad Ihsan Muttaqin, Manaman Huang, Usman Sumo Friend TambunanTuberculosis is a global leading cause of death, just below COVID-19 and ranked above HIV. This disease is caused by a pathogen called Mycobacterium tuberculosis, which spreads easily through the air and is known to remain latent in most people's bodies, about a quarter of the world's population. The current problems with TB also include two main concerns: The official … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 14 Mar 2024 · 5,518 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleSelf-Assembly Peptides-a ReviewOlushola Sunday Ayanda, Olusola Solomon Amodu, Cyprian Yameso Abasi et al.Self-assembling of peptides is a spontaneous process by which peptides are self-organized to form well-ordered structures by intramolecular and intermolecular interactions.This process is controlled by the balance of the forces (attractive andrepulsive) within the peptide molecules. Notable methods used for the synthesis of self-assembly peptides are solid-phase synthesis, liquid-phase synthesis,recombinant technology, and the use of external fields. The self-assembled nanostructure-based … …OnLine Journal of Biological Sciences, Vol. 22, Issue 3 · 12 Aug 2022 · 5,739 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComparison of Ferrous Ion Chelating Properties of Collagen Peptides from Dried and Fresh Cod SkinMengqian Chen, Cen Chen, Junchao Wu et al.Fish skin is a potential source of collagen and collagen is a protein source of bioactive peptides including iron chelating peptides. The aim of this study is to compare physicochemical properties of collagen extracted from fresh and dried cod skin and the ferrous ion chelating properties of collagen hydrolysates. Then the fresh and dried cod skin extracted collagen was hydrolyzed … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 2 Jul 2021 · 7,155 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Use of α-MF Signal Peptide Without Spacer for Producing Insulin Aspart Precursor in Pichia pastoris KM71Popi Asri Kurniatin, Fifi Fitriyah Masduki, Neni Nurainy et al.A spacer peptide (Glu-Ala repeats) connects N-terminal of a polypeptide precursor to the signal peptide of α-mating factor (α-MF) from Saccharomyces cerevisiae. During the polypeptide precursor secretion, the signal peptide will be first cleaved by signal peptidase in the endoplasmic reticulum, followed by Kex2 endopeptidase and finally the spacer peptide is removed by dipeptidyl aminopeptidase in the Golgi apparatus. In … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 31 Oct 2019 · 9,026 accessesView PDFCite
Research NotesOpen accessEvery word in the titleAn Artificial Design Technique to Optimize Signal PeptideGao Cui-Fang, Wang Sen, Tian Feng-Wei et al.To determine optimal artificial signal peptide candidates for the possibility of creating high levels of secretion of heterologous proteins, substitution and redesign of amino acid sequences in the H-domain of the signal peptide was theoretically attempted. The method was based on comprehensive score matrix and Markov transfer matrix, which can make the artificial sequences maintain the structural characteristics and original … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 3 · 21 Jul 2017 · 8,063 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDesigning of Disulfide Cyclic Peptide for Inhibiting Polymerase A and B1 (PAC-PB1N) in H1N1 Virus using Molecular Simulation ApproachUsman Sumo Friend Tambunan, Mochammad Arfin Fardiansyah Nasution, Arli Aditya Parikesit et al.The drug resistance A/H1N1 flu virus is emerging rapidly. Therefore, looking for potential therapy is very important. PB2, PB and PA are subunits of viral RNA-dependent RNA polymerase (RdRp). They play an important role in viral replication. The PA and PB1 binding sites can be considered as potential targets for the development of new influenza drugs. The peptide inhibitors can … …OnLine Journal of Biological Sciences, Vol. 16, Issue 3 · 24 Aug 2016 · 7,310 accessesView PDFCite