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99 results for “Genetic Factor”
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Research ArticleOpen accessIn the abstractLEUKOTRIENE C4 SYNTHASE AND LEUKOTRIENE RECEPTOR-1 GENES POLYMORPHISM AMONG ATOPIC ASTHMATIC PATIENTSHeba M. Kadry, Amal H. Atta, Mostafa K. Sultan, Nagwa A. El-BazAsthma is a complex polygenic disease in which Cysteinyl Leukotrienes (Cys-LTs) are a potential risk factors causing airway inflammation and remodeling, which are characteristics of asthma. The polymorphisms in the leukotriene C4 synthase -444A/C and cysteinyl leukotriene receptor1 927 T/C genes has been implicated in susceptibility to asthma. The objective of this study was to analyse two different polymorphisms, LTC4S-444 … …American Journal of Immunology, Vol. 10, Issue 2 · 5 May 2014 · 7,379 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Assessment of Echocardiography as a Diagnostic Tool for Dilated Cardiomyopathy in Turkey (Meleagris gallopavo)Davida Kamara, Kwaku Gyenai, Tuoyu Geng et al.Our understanding of the etiology of Dilated Cardiomyopathy (DCM), which affects about 5% of turkeys, is limited. This limitation may be due to the lack of an easy-to-use diagnostic tool with well-defined parameters and does not involve necropsy. This lack of a widely tested non-necropsy method makes it difficult for a large-scale study of the genetic factors that underlie DCM. … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 3 · 15 Aug 2012 · 8,451 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Splay Leg Syndrome in Piglets: A ReviewVassilis G. PapatsirosProblem statement: The splay leg syndrome is the major congenital cause of lameness in suckling piglets. It is characterized by a temporarily impaired functionality of the hind leg muscles immediately after birth, resulting in an ability to stand and walk. Etiology and pathogenesis is complex and remain still poorly understood. Approach: The aim of the present study is to perform … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 2 · 19 Jul 2012 · 10,085 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Prospective Evaluation of Antihypertensive Medications Safety and Efficacy in United Arab Emirates Private HospitalsMuaed Jamal Alomar, Claire Caroline StrauchProblem statement: Hypertension is one of the most important risk factors for heart and cardiovascular diseases in the United Arab Emirates (UAE). Evaluation of the safety and efficacy of antihypertensive medications in UAE private hospitals is important. The importance arises because of the high prevalence of hypertension in this multicultural region. This study evaluated the use of antihypertensive medications among … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 8,312 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Dynamics Studies of Human β-GlucuronidaseIbrahim Ali Noorbatcha, Ayesha Masrur Khan, Hamzah Mohd SallehProblem statement: The enzyme β-glucuronidase is being used as a reporter molecule in the area of genetic engineering, as a component of prodrug therapy in cancer treatment and in the scouring process of cotton fabrics. However, a detailed understanding of the factors responsible for the stability and the activity of this enzyme is still not available. Molecular Dynamics (MD) simulations … …American Journal of Applied Sciences, Vol. 7, Issue 6 · 30 Jun 2010 · 7,613 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction Scheduling for Dispatching Ready Mixed Concrete Trucks Using Bee Colony OptimizationSakchai Srichandum, Thammasak RujirayanyongProblem statement: This study proposed a systematic model of delivering Ready Mixed Concrete (RMC) that optimizes the schedule of dispatching RMC trucks. Approach: Firstly, the factors that impact the RMC delivery process are analyzed. Secondly, a model based on Bee Colony Optimization (BCO) was developed in order to find the best dispatching schedule that minimize the total waiting time of … …American Journal of Engineering and Applied Sciences, Vol. 3, Issue 1 · 31 Mar 2010 · 9,322 accessesView PDFCite
Research ArticleOpen accessIn the abstractConcentration of Zn, Cu and Pb in Some Selected Marine Fishes of the Pahang Coastal Waters, MalaysiaB. Y. Kamaruzzaman, M. C. Ong, S. Z. RinaProblem statement: Heavy metals constitute one of the most hazardous substances that could be accumulated in biota. Fish populations exploited by man often live in coastal area environments that contain high levels of heavy metals, coming from human activities such as industrial and agricultural wastes. A problem to deal when using fishes as biomonitors of heavy metals is the relationship … …American Journal of Applied Sciences, Vol. 7, Issue 3 · 31 Mar 2010 · 10,004 accessesView PDFCite
Research ArticleOpen accessIn the abstractEssential Oil of Tanacetum parthenium (L.) from East Part of KosovaArben Haziri, Sevdije Govori-Odai, Murtezan Ismaili et al.Problem statement: We have analyzed the chemical nature of essential oil of Tanacetum parthenium (L.) from East part of Kosova. Approach: The essential oil from aerial part of Tanacetum parthenium (L.), obtained by hidro-distillation was analyzed by GC and GC-MS. Results: Out of 25 peaks, 22 components, which constitute 88%, were identified in oil. The main compounds of Tanacetum parthenium … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 4 · 31 Dec 2009 · 7,130 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Mitochondrial Dysfunction in Autism and Implications for TreatmentDaniel A. Rossignol, J. Jeffrey BradstreetClassical mitochondrial diseases occur in a subset of individuals with autism and are usually caused by genetic anomalies or mitochondrial respiratory pathway deficits. However, in many cases of autism, there is evidence of mitochondrial dysfunction (MtD) without the classic features associated with mitochondrial disease. MtD appears to be more common in autism and presents with less severe signs and symptoms. … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 16,373 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolic Abnormalities Associated with the Use of Protease Inhibitors and Non-nucleoside Reverse Transcriptase InhibitorsMadhu N. Rao, Grace A. Lee, Carl GrunfeldThe use of protease inhibitors and non-nucleoside reverse transcriptase inhibitors for the treatment of HIV infection and AIDS has been associated with multiple abnormalities in glucose and lipid metabolism. Specifically, these abnormalities include insulin resistance, increased triglycerides and increased LDL cholesterol levels. The metabolic disturbances are due to a combination of factors, including the direct effect of medications, restoration to … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,936 accessesView PDFCite