Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

109 articles for “specific target”
Set a search alert
Review ArticleOpen accessIn the abstractThe Effect of Main Heat Shock Proteins on AtherosclerosisAnastasia Vladimirovna Poznyak, Alexey V. Churov et al.Atherosclerosis is a multifaceted disease characterized by complex pathogenesis involving diverse mechanisms. In recent years, the autoimmune nature of atherosclerosis has gained significant attention, emphasizing the indispensable role of the immune system in its initiation and progression. Heat Shock Proteins (HSPs) are vital for cellular functionality, facilitating cellular adaptation to environmental changes and survival under adverse conditions. Notably, various HSP … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 3 Oct 2024 · 4,354 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Soil Storage at Freezing Temperatures on Soil Enzymatic ActivitiesAinsley Lougheed, Kabwe NkongoloSoil enzyme activities are good indicators of soil health. It has been hypothesized that soil storage before analysis might affect microbial function. The objective of the present study was to determine if soil storage at -20 and -80°C affects soil enzymatic activities. Soil samples were collected and stored for four weeks at -20 and -80°C. Activities of nine enzymes were … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 3 · 12 Aug 2024 · 4,984 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of Vascular Smooth Muscle Cells, Endothelial Cells, and Macrophages Apoptosis During Atherosclerosis DevelopmentAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a complex disease that has garnered significant attention from researchers studying its various aspects. Its pathogenesis involves a wide array of cellular and molecular components, as well as crucial mechanisms and processes crucial for cellular and organismal functioning. Atherosclerosis is considered a chronic inflammatory disease characterized by disrupted lipid metabolism, oxidative stress, and immune response. Apoptosis, a fundamental … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,675 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation Rate and Species Distribution of Non-Tuberculous Mycobacteria From 2014-2021Tae Soung Kim, Ga Yeon Kim, Young Ki Lee, Jae Kyung KimIn Korea, the incidence of Mycobacterium tuberculosis infections has decreased; however, the incidence of lung diseases attributed to Non-Tuberculous Mycobacteria (NTM) is increasing. This study aimed to elucidate the isolation rate and distribution of NTM recently isolated at a Korean test center. Respiratory samples for acid-fast bacilli culture collected between January 2014 and December 2021 at a test center in … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 13 Nov 2023 · 4,983 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring Data Augmentation for Gender-Based Hate Speech DetectionMuhammad Amien Ibrahim, Samsul Arifin, Eko Setyo PurwantoSocial media moderation is a crucial component to establish healthy online communities and ensuring online safety from hate speech and offensive language. In many cases, hate speech may be targeted at specific gender which could be expressed in many different languages on social media platforms such as Indonesian Twitter. However, difficulties such as data scarcity and the imbalanced gender-based hate … …Journal of Computer Science, Vol. 19, Issue 10 · 29 Sep 2023 · 5,550 accessesView PDFCite
Research ArticleOpen accessIn the abstractLevels of Metals and Microbial Biomass in Cobalt Coleman Mine Tailings (Canada) Three Decades after Land ReclamationKabwe Nkongolo, Graeme Spiers et al.Investigations of restored metal contaminated tailings in Canada with regard to their long-term ability to sustain plant and associated microbiological populations are limited. The specific objectives of the present study were to assess (1) The current levels of total and bioavailable metals and (2) Microbial biomass in Cobalt Coleman mine tailings reclaimed in 1990. The level of microbial biomass was … …American Journal of Environmental Sciences, Vol. 19, Issue 1 · 20 Mar 2023 · 6,004 accessesView PDFCite
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Practical Framework for the Continuous Advancement of Entrepreneurship EducationRobin Anderson, Brooke R. Envick, Prasad PadmanabhanProblem statement: As the business environment becomes more and more complex due to rapid globalization, increasing competition and advancing technologies, universities are under more pressure to respond by providing students with experiential learning opportunities that mirror reality. In this study, we attempt to provide a better learning experience for students. Specifically, we provide a framework from a student learning perspective … …American Journal of Economics and Business Administration, Vol. 4, Issue 1 · 25 Feb 2012 · 8,100 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring Factors Affecting on Willingness to Observe Air Pollution Reduction Policies in Tehran, IranPejman Jafari, Afrooz BotshekanOne of the most important issues of these days is an environmental pollution. Environmental problems such as air pollution and climate changes in urban areas are the results of human behavior. Only change in human behavior can reduce these environmental problems. Thus, studying attitude and behavior of people is a precondition to change this situation. This study aimed to examine … …American Journal of Environmental Sciences, Vol. 17, Issue 1 · 1 Jun 2021 · 7,799 accessesView PDFCite