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80 articles for “MDA”
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Research ArticleOpen accessIn the abstractIMPACT OF DEHYDROEPIANDROSTERONE IN PREVENTION OF PARACETAMOL INDUCED NEPHROTOXICITY IN RATSAbbas O. ElkaribParacetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the event. However, Dehydroepiandrosterone (DHEA), the major secretory product of the human adrenal gland, has been shown to possess a multi-targeted antioxidant activity which is also effective against lipid peroxidation induced in various animal models and against various human disorders. In this study, the … …Current Research in Medicine, Vol. 5, Issue 1 · 26 Mar 2014 · 7,566 accessesView PDFCite
Research ArticleOpen accessIn the abstractEVALUATION OF THE ANTI-ARTHRITIC EFFECT OF STERCULIA TRAGACANTHA (LINDL.) LEAF EXTRACT IN RATSUdegbunam Rita Ijeoma, Nwaehujor Chinaka Onyebuchi, Udegbunam Sunday OsitadimmaSterculia tragacantha leaves for years have been used by traditional healers in eastern Nigeria in the treatment of arthritis, edema, gout, whitlow and cold. The aim of this study was to evaluate the folkloric claims of Sterculia tragacantha leaf extract in relieving arthritic conditions. The effects of Sterculia Tragacantha methanol leaf Extract (STEX) on formaldehyde and adjuvant-induced arthritis were studied … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 11 Mar 2014 · 7,588 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECTS OF UV-B ON PHOTOSYNTHETIC PARAMETERS, LIPID PEROXIDATION, FLAVONOIDS AND GROWTH TRAITS OF CONOCARPUS LANCIFOLIUS (ENGL.)Patrice Suleman, Amina Redha, Mohamad Afzal, Redha Al-HasanConocarpus lancifolius is a perennial ornamental plant adapted to the semi-arid conditions of Kuwait. It accumulates most of its biomass during the stressful summer conditions which includes UV-B irradiation. The study evaluated equivalent UV-B irradiation intensities that plants would normally experience sometime during the course of a year in Kuwait. Leaf area, plant height, photosynthetic parameters, Lipid Peroxidation (LP) and … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 1 · 23 Dec 2013 · 7,548 accessesView PDFCite
Research ArticleOpen accessIn the abstractSilkworm Pupae Protect Against Alzheimer’s DiseaseJintanaporn Wattanathorn, Supaporn Muchimapura, Artit Boosel et al.Silkworm (Bombyx mori) pupae have long been used as food and medicine in Asian countries. It is reputed for the treatment of numerous neurological disorders related to oxidative stress including stroke. Therefore, we hypothesized that silkworm pupae could attenuate memory impairment and neurodegeneration in Alzheimer’s disease. In the present study, we determined the effect of silkworm pupae on the neurodegeneration … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 16 Aug 2012 · 9,697 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Lam Mitigates Oxidative Damage and Brain Infarct Volume in Focal Cerebral IschemiaWoranan Kirisattayakul, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Problem statement: At present, the therapeutic outcome of cerebral ischemia is still not in the satisfaction level. Therefore, the preventive strategy is considered. Based on the protective effect against oxidative damage of Moringa oleifera Lam. Leaves extract, we hypothesized that this plant extract might protect against cerebral ischemia, one of the challenge problems nowadays. In order to test this hypothesis, … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 3 Aug 2012 · 7,574 accessesView PDFCite
Research ArticleOpen accessIn the abstractCardioprotective Effect of Lagenaria siceraria (Molina) Standley (Cucurbitaceae) Fruit Juice on Doxorubicin Induced Cardiotoxicity in RatsM. Hassanpour Fard, G. Naseh, S. L. Bodhankar, M. DikshitProblem statement: The cardio toxicity of Doxorubicin (Dox) has limited its use as an anticancer drug. The aim of present study was to investigate the cardio protective effect of Lagenaria Siceraria (Cucurbitaceous) Fruit Juice (LSFJ) against the cardio toxicity of Dox in rats. Approach: Male wistar rats (250-300 g) were randomly divided into four groups. Group I- was control, Group … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 8,510 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Garcinia Atroviridis on Oxidative Stress and Atherosclerotic Changes in Experimental Guinea PigsAdel. A. Amran, Zaiton Zakaria, Faizah Othman, Paden MoratProblem statement: Oxidative stress plays a major role in hypercholesterolemia induced atherosclerosis. Garcinia atroviridis has been shown to exhibit antioxidant properties. Approach: The present study aimed to investigate the effect of Garcinia atroviridis on the oxidative stress in guinea pigs fed with high cholesterol diet. Twenty-four male Guinea pigs were divided into four groups. Group I served as control while … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,035 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Camel's Milk on Cisplatin-Induced Nephrotoxicity in Swiss Albino MiceMohamed E.M. AfifiProblem statement: Nephrotoxicity is a major complication and a dose limiting factor for cisplatin therapy. Cisplatin mediated nephrotoxicity is remarkably documented by reactive oxygen species. Camel's milk has good nutritive value, antigenotoxic and anticytotoxic effects. The aim of the present study was to assess the protective effect of camel's milk against Cisplatin-induced renal oxidative stress in mice. Approach: Forty mal … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,989 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn the Predictability of Risk Box Approach by Genetic Programming Method for Bankruptcy PredictionAlireza Bahiraie, Noor Akma bt Ibrahim, A. K.M. AzharProblem statement: Theoretical based data representation is an important tool for model selection and interpretations in bankruptcy analysis since the numerical representation are much less transparent. Some methodological problems concerning financial ratios such as non-proportionality, non-asymetricity, non-scalicity are solved in this study and we presented a complementary technique for empirical analysis of financial ratios and bankruptcy risk. Approach: This study … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 7,948 accessesView PDFCite
Research ArticleOpen accessIn the abstractQUERCETIN AMELIORATES DIABETIC NEPHROPATHY IN RATS VIA MODULATION OF RENAL NA+, K+-ATPASE EXPRESSION AND OXIDATIVE STRESSSalah O. Bashir, Mohamed Darwesh Morsy, Hussein F. Sakr et al.Diabetic Nephropathy (DN) is one of most prevalent complications of Diabetes Mellitus (DM), therefore prevention of its development is a important field for researches. Quercetin is a plant flavenoid with hypoglycemic and antioxidant properties that is claimed to have a reno-protective effect in diabetes. This study was designed to investigate the reno-preventive role of Quercetin treatment in terms of biochemical … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 14 Feb 2014 · 8,047 accessesView PDFCite