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241 articles for “Lipid”
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Research ArticleOpen accessIn the keywordsMetabolic Abnormalities Associated with the Use of Protease Inhibitors and Non-nucleoside Reverse Transcriptase InhibitorsMadhu N. Rao, Grace A. Lee, Carl GrunfeldThe use of protease inhibitors and non-nucleoside reverse transcriptase inhibitors for the treatment of HIV infection and AIDS has been associated with multiple abnormalities in glucose and lipid metabolism. Specifically, these abnormalities include insulin resistance, increased triglycerides and increased LDL cholesterol levels. The metabolic disturbances are due to a combination of factors, including the direct effect of medications, restoration to … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,941 accessesView PDFCite
Review ArticleOpen accessIn the keywordsJAK Inhibitors for Rheumatoid Arthritis: Assessing Efficacy and Safety in TreatmentAnastasia V. Poznyak, Varvara A Orekhova, Natalia Vladimirovna Elizova et al.Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, progressive joint destruction, and systemic complications. Dysregulated cytokine signaling through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway plays a central role in RA pathogenesis, making JAK inhibitors an important therapeutic option. Tofacitinib, baricitinib, and upadacitinib are oral targeted synthetic disease-modifying antirheumatic drugs that interfere with … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 8 Oct 2026 · 430 accessesView PDFCite
Research ArticleOpen accessIn the keywordsInverse Correlation Between α-Klotho and Diabetic Biomarkers in Type 2 Diabetes: A Cross-Sectional StudyYaser A.M Sulaiman, Moayad M. Al Anzy, Omeed Akbar Ali, Adnan M. IsmailEvidence suggests a link between diabetes and Klotho protein, demonstrated by reduced Klotho gene expression in individuals with diabetes, α- klotho the potential modulator of kidney health in DM. Klotho is primarily expressed in the kidneys and has an anti-inflammatory and antioxidant role, which may protect against the pathological processes that damage renal function in diabetes. Research conducted in Japan … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 843 accessesView PDFCite
Review ArticleOpen accessIn the keywordsVLDL in Atherosclerosis: Variety of Mechanistic ImplicationsAnastasia Vladimirovna Poznyak, Victor Yurievich Glanz, Vasily Nikolaevich Sukhorukov et al.Very-Low-Density Lipoprotein (VLDL) particles play a pivotal role as precursors for Intermediate-Density Lipoprotein (IDL) and eventually transform into Low-Density Lipoprotein (LDL). These particles have been categorized based on size and particle charge. Various types of VLDL impact diverse physiological processes in the human body. The accumulation of VLDL, along with other triglyceride-rich lipoproteins, significantly contributes to the development of atherosclerotic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 29 Jul 2024 · 4,314 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRole of the Wnt/β-Catenin Signaling Pathway in Reducing Lipogenesis of Obese Rats Under Hypoxic ExercisePeiming Xu, Zhiyuan Sun, Xiaoyi Tian et al.Hypoxic exercise exerts a significant effect on body weight loss and body fat reduction. Methods: In the present study, we constructed an obese rat model and divided rats into the following groups: Normoxic quiet (C), Hypoxic quiet (H), Normoxic Exercise (CE), and Hypoxic Exercise (HE). We employed isobaric tags for relative and absolute quantification (iTRAQ) using proteomic technology to screen … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 3 Jun 2022 · 5,744 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLIPASE-CATALYZED TRANSESTERIFICATION OF PALM KERNEL OIL WITH DIALKYLCARBONATESTjahjono Herawan, M. Rüsch Gen. KlaasLipase-catalyzed transesterifications-especially in a solvent-free medium-are important for industrial applications because such systems would have an enormous advantage by avoiding the problem of separation, toxicity and flammability of organic solvents. However, the organic solvent-free alcoholysis, especially methanolysis, does not give high conversions. The same problem also occurs when ethyl or methyl acetate are used as acyl acceptors. The main problems … …American Journal of Applied Sciences, Vol. 11, Issue 8 · 6 May 2014 · 6,798 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDetermination and Evaluation of Antioxidative Activity in Red Dragon Fruit (Hylocereus undatus) and Green Kiwi Fruit (Actinidia deliciosa)Normala Halimoon, Mardhiah Hayati Abdul HasanProblem statement: Dragon fruit or pitahaya (Hylocereus undatus), is believed to be a healthy source of vitamins, fiber and antioxidants, especially the red-fleshed varieties which contain lycopene. Approach:Compared to green kiwi fruit (Actinidia deliciosa), which already known contain high antioxidant activity. Results:The antioxidant capacity of Hylocereus undatus (H. undatus) and Actinidia deliciosa (A. deliciosa) in three different solvent extraction; ethanol, … …American Journal of Applied Sciences, Vol. 7, Issue 11 · 8 Nov 2010 · 9,160 accessesView PDFCite
Research ArticleOpen accessIn the keywordsLipoprotein (a) and Apolipoprotein (a) Isoforms in Patients with Acute Myocardial InfarctionAkram Saleh, Izzat AL-Awwaa, Sally Awwadeh, Nabil BashirProblem statement: The objective of this study is to determine the relationship between plasma lipoprotein (a) levels and apolipoprotein (a) isoforms in a group of Jordanian patients with Acute Myocardial Infarction (AMI) Approach: A total of 90 patients with acute myocardial infarction were compared with 90 age-and sex-matched controls. Lipoprotein (a) levels were measured by ELIZA method and isoforms were … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,536 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHypolipidemic Effects of Coenzyme Q10 in Experimentally Induced Hypercholesterolemic Model in Female RatsAtef M. Al-AttarProblem statement: Hyperlipidemia is well known to play a main role in the development of atherosclerosis. It is characterized by abnormally elevated cholesterol, triglyceride, low density lipoprotein cholesterol and very low density lipoprotein cholesterol levels in the blood. It has been recognized for many years that hypercholesterolemia is a major risk factor for cardiovascular diseases such as atherosclerosis, myocardial infraction, … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 45,651 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHepatoprotective Activity of Aqueous Ethanolic Extract of Chamomile capitula in Paracetamol Intoxicated Albino RatsAjay k. Gupta, Neelam MisraHepatoprotective activity of aqueous ethanolic extract of Chamomile recutita capitula against paracetamol induced hepatic damage in albino rats was observed. In the present study the effect of aqueous ethanolic extract of Chamomile recutita capitula on blood and liver glutathione, Na+ K+- ATPase activity, serum marker enzymes, serum bilirubin, glycogen and thiobarbutiric acid reactive substances against paracetamol induced damage in rats … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 18,953 accessesView PDFCite