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92 results for “Cytokines”
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Research ArticleOpen accessIn the abstractSerum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet BAhmad Taha Khalaf, Yan YuehuaAlthough it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-β and TNF-α necessary for understanding the underlying … …American Journal of Applied Sciences, Vol. 11, Issue 12 · 6 Jan 2015 · 6,095 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition of Interleukin-6 Expression by Curcumin in Rat Vascular Smooth Muscle Explants In VitroYanti, Stephanie, Yuliani et al.In atherosclerotic plaques, infectious agents from microbes may release Lipopolysaccharide (LPS) and heat shock proteins that can stimulate the production of mediators, i.e., pro-inflammatory cytokines, by vascular endothelial cells and Smooth Muscle Cells (SMCs). The elevated level of Interleukin-6 (IL-6) is strongly associated with the development of atherosclerosis. Here, we investigated whether curcumin isolated from the rhizome of Curcuma longa … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 15 Dec 2014 · 6,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECT OF ZINC OXIDE NANOPARTICLES ON NEUROBLASTOMA SH-SY5Y CELLSJinghui Zheng, Theresia Schnurr, Kriya Dunlap et al.The Arctic and sub-arctic regions are impacted by the growth of the global nanotechnology industry and the transport of chemicals to the North. New nanotechnology industries, such as neural prothesis, are bringing nanomaterials in direct contact with neurons and glial cells. Nanomaterials have unique chemical and physical properties that may lead to toxicological effects by interfering with normal cellular metabolism. … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 2 · 4 Jul 2014 · 8,490 accessesView PDFCite
Research ArticleOpen accessIn the abstractMORINGA TEA BLOCKS ACUTE LUNG INFLAMMATION INDUCED BY SWINE CONFINEMENT DUST THROUGH A MECHANISM INVOLVING TNF-α EXPRESSION, C-JUN N-TERMINAL KINASE ACTIVATION AND NEUTROPHIL REGULATIONMykea Mcknight, Jabria Allen, Jenora T. Waterman et al.Plant based products represent a promising alternative to conventional treatments for inflammation. Moringa oleifera Lam is a tree rich in proteins, vitamins, minerals and a variety of phytochemcals with health benefits. Among the reported health benefits are antioxidant and anti-inflammatory properties. The purpose of this study was to investigate whether tea brewed from dried Moringa leaves would abrogate inflammation in … …American Journal of Immunology, Vol. 10, Issue 2 · 8 May 2014 · 11,603 accessesView PDFCite
Research ArticleOpen accessIn the abstractHYPOXIC INFLAMMATION, A DEADLY BRIDGE TO MALIGNANT TRANSFORMATION AND A FERTILE SOIL FOR CANCER PREVENTIONKambiz Afrasiabi, Robert Edwards, Jonathan Melekh-Shalom, Kehui WangThe interplay of the inflammatory microenvironment with its hypoxic niche and the potential mechanism by which they lead to malignant transformation has long been the subject of great controversy and continues to be an area of great interest today. In our previous studies we have examined this subject by using Gia2 knock out mice as the focus of our research. … …OnLine Journal of Biological Sciences, Vol. 13, Issue 3 · 4 Sep 2013 · 7,149 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical Alterations Induced by Amylin in Wistar RatsMohamed Mohamed Soliman, Zein Shaban IbrahimAmylin is a peptide hormone synthesized in β cells of pancreas together with insulin in response to glucose and nutrients. Amylin controls food intake and body weight but the exact mechanism is still unknown. This study aimed to examine the effects of amylin injection on hormones, metabolites and cytokines expression in rats. Wistar rats were injected amylin Intraperitoneally (IP) (10 … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 7 Jun 2013 · 6,771 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioinformatics Analysis of Some Functional Genes and Proteins Involved in Obesity-Induced Type 2 DiabetesEhab M. Abdella, Rasha R. Ahmed, Mohamed B. Ashour et al.The incidence of type-2 diabetes is rising rapidly worldwide, mainly because of the increase in the incidence of obesity, which is an important risk factor for this condition. Both obesity and type-2 diabetes are complex genetic traits but they also share some nongenetic risk factors. Differences among individuals in their susceptibility to both these conditions probably reflect their genetic constitutions. … …Current Research in Bioinformatics, Vol. 1, Issue 2 · 6 May 2013 · 12,612 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Innate Immunity in Bovine Mastitis: The Role of Pattern-Recognition ReceptorsFernando Nogueira de Souza, Eduardo Milton Ramos Sanchez, Marcos Bryan Heinemann et al.Mastitis is the most costly disease for dairy farmers and industry, which are mainly caused by the entry of bacteria to the teat canal. Shortly after the entry of the invading bacteria, the innate immunity recognizes the invading pathogen through pattern recognition receptors and initiates the inflammatory response necessary to eliminate the invading bacteria. This initial inflammatory response releases cytokines … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 10,357 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Inflammation in Development and Therapy of Malignant MesotheliomaArti Shukla, Jill MillerMalignant Mesothelioma (MM) is an asbestos related malignancy with a poor prognosis and limited therapeutic approaches. The pathogenesis of MM has been linked to asbestos induced inflammation. Asbestos exposure results in reactive oxygen species generation, infiltration of inflammatory cells and prolonged release of multiple cytokines, oxidants and growth factors. The role of inflammation in MM has led to the evaluation … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,439 accessesView PDFCite
Research ArticleOpen accessIn the abstractDietary β-glucan Leads to Increased TNF-α Production in the LungRadiah C. Minor, Melody L. Robinson-Wright, Morika Williams, Steven L. HurleyProblem statement: Beta (β)-glucan is notable for its ability to stimulate the immune system and as such β-glucan and products containing β-glucan are used as dietary supplements for livestock and companion animals. β-glucan has been shown to activate macrophages and neutrophils and modulate the production of certain cytokines, including the pro-inflammatory cytokine, Tumor Necrosis Factor Alpha (TNF-α). Because TNF-α is … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 2 · 11 Jun 2012 · 7,510 accessesView PDFCite