Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B
Ahmad Taha Khalaf1 & Yan Yuehua2 Show affiliations
- Department of Dermatology, Faculty of Medicine, Mosul Medical College, Mosul University, Mosul, Iraq
- Zhongnan Hospital of Wuhan University, Wuhan 430071, China
American Journal of Applied Sciences, Volume 11, Issue 12, pp. 1992–1994 · doi.org/10.3844/ajassp.2014.1992.1994
Abstract
Although it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-β and TNF-α necessary for understanding the underlying mechanisms of narrow-band UVB phototherapy. NB-UVB is effective against psoriasis without any obvious side effects and can significantly decrease serum TNF-α and promote TGF-β level of psoriasis patients. Additionally, measurement of TGF-β and TNF-αin serum could be considered as biomarkers of psoriasis activity during NB-UVB therapy.
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Khalaf, A. T. & Yuehua, Y. (2014). Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B. American Journal of Applied Sciences, 11(12), 1992–1994. https://doi.org/10.3844/ajassp.2014.1992.1994
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