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89 articles for “Biomarker”

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Research ArticleOpen accessIn the abstractToxicological Consequences of Di-N-Butyl-Phthalate (DBP) on Health of Nile Tilapia FingerlingsEhsan H. Abu Zeid, Al Shimaa A. KhalilPhthalic Acid Esters (PAEs) are mainly used in the plastics industry as adhesives and plasticizers. Di-n-Butyl Phthalate (DBP) is one of the important members in the family of PAEs was listed as environmental priority pollutants by the US Environmental Protection Agency. The objective of this study was to evaluate the toxicological consequences in Nile Tilapia Oreochromis niloticus L. fingerlings, exposed … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 8,466 accessesView PDFCite
Research ArticleOpen accessIn the abstractDrug-Protein Interactions for Clinical Research by Nucleic Acid Programmable Protein Arrays-Quartz Crystal Microbalance with Dissipation Factor Monitoring Nanoconductometric AssayClaudio Nicolini, Rosanna Spera, Nicola Luigi Bragazzi, Eugenia PechkovaConductometric monitoring of drug-gene and drug-protein interactions is of fundamental importance in the field of molecular pharmacology. Here, we present our main findings and characterizations of an important antiblastic used in neuro-oncology (Temozolomide), interacting with selected proteins that represent predictive biomarkers of the rate survival of the patients, of the outcome of chemotherapy and resistance to drug itself (namely, BRIP1 … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 17 Nov 2014 · 8,506 accessesView PDFCite
EditorialOpen accessIn the abstractTREATMENT FOR ANOREXIA NERVOSA: ARE WE MISSING THE MARK?Peta Stapleton, Amy BannatyneAPA, 2013. Diagnostic and Statistical Manual of Mental Disorders, 5th Edn., Arlington, VA: American Psychiatric Publishing. APA, 2014. Anorexia nervosa. www.psychologicaltreatments.org Ben-Tovim, D., K. Walker, P. Gilchrist, R. Freeman and R. Kalucy et al., 2001. Outcome in patients with eating disorders: A 5-year study. Lancet, 357: 1254-1257. DOI: 10.1016/S0140-6736(00)04406-8 Beumont, P.J.V. and S. Touyz, 2003. What kind of illness is … …Current Research in Psychology, Vol. 5, Issue 2 · 20 Sep 2014 · 9,541 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicrornas as Double Edged Sword in CancerBaby Joseph, Vrundha M. NairCancer is the leading causes of death world wide. Basically it can be defined as the disease of the cell. One among the mechanism of transfer of a normal cell to cancerous is the alteration in the genetic material DNA. Treatment for cancer remains as a biggest challenge. Here comes the importance of miRNAs. They are endogenous RNA which regulates … …Current Research in Bioinformatics, Vol. 2, Issue 1 · 24 May 2013 · 6,953 accessesView PDFCite
Research ArticleOpen accessIn the abstractConcentration-Effect, Incidence and Mechanism of Nevirapine HepatotoxicityAdikwu Elias, Brambaifa NelsonNevirapine is a dipyridozepinone non nucleoside reverse transcriptase inhibitor approved for use in HIV-infected patients. Its efficacy has been well demonstrated in numerous clinical trials. It has activity against HIV-1 but does not have significant activity against HIV-2 or other retroviruses. Nevirapine is used as one of the components of highly active antiretroviral therapy in HIV patients and in the … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 19 Apr 2013 · 8,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractAcute Phase Proteins, Lipid Profile and Proinflammatory Cytokines in Healthy and Bronchopneumonic Water Buffalo CalvesSabry M. El-Bahr, Wael M. EL-DeebThe aim of the present study was to evaluate the diagnostic value of Acute Phase Proteins (APP), lipid profiles and proinflammatory cytokines in healthy and bronchopneumonic water buffalo calves. Therefore, sixty water buffalo calves (9±1 month old, 175±15 kg) were divided into two equal groups, the first group represented healthy, control, calves whereas calves of the second group were affected … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 8,415 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Mechanisms in Hepatitis C Virus-Associated Hepatocellular Carcinoma: A Potential New Link Between Stem Cells, Virology and CancerQinghua Feng, Sajida Hassan, Trina Das et al.Recent studies suggest that epigenetic mechanisms are not only essential for the dynamic transcriptional regulation in embryonic and somatic stem cells, but are also actively involved in tumorigenesis: genes important for pluripotency are epigenetically regulated and aberrant epigenetic changes have been detected in virtually all human malignancies studied, including Hepatocellular Carcinoma (HCC). Infection with Hepatitis C Virus (HCV) is a … …Current Research in Medicine, Vol. 4, Issue 1 · 12 Mar 2013 · 8,038 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Review of Biochemical Markers for Early Diagnosis of Alzheimer’s DiseaseMeha Fatima Aftab, Rizwana S. WaraichAlzheimer’s disease, the most prevalent type of dementia, affects the life of elderly, to such extent that it impairs the ability to perform routine functions as well. The impairment of normal functions not only affects the patients but the family members as well. It is difficult to make a definitive diagnosis; hence some clinical and psychological tools are used to … …Neuroscience International, Vol. 3, Issue 2 · 4 Sep 2012 · 13,511 accessesView PDFCite
Research ArticleOpen accessIn the abstractPaleolithic-Style Diet and Coronary Artery Disease: The Tissue is the Issue?Eri Toda, Takahashi Toru, R. B. Singh et al.Approach: While the Western diet is proatherogenic, Paleolithic-style diet may be protective against Cardiovascular Diseases (CVDs). Results: Western diet is characterized with energy dense, refined, foods with a high glycemic index (e.g., refined starches; biscuits and bread) and unhealthy lipids (e.g., trans fats, saturated fat, omega-6 rich oils) poor in omega-3 fatty acids, phytochemicals and fibre. These diets are known … …Current Research in Medicine, Vol. 3, Issue 2 · 10 Aug 2012 · 7,135 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlatelets, Coagulation and Cancer: Multifaceted InteractionsT. Burnouf, H. A. GoubranApproach: Literature review of the multifaceted interactions between platelets, coagulation and cancer. Results: Over the years, the links existing between cancer development, progression and occurrence of metastasis on one side and coagulation on the other have become obvious. Tumors seems to activate platelets whereas, platelets, on the other hand, through their capacity to activate and release soluble factors and microparticles, … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Jul 2012 · 7,613 accessesView PDFCite