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304 results for “rats”
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Research ArticleOpen accessEvery word in the titleGreen Tea Treatment Attenuates Oxidative Damage and Neuromotor Deficit Induced by an Experimental Model of Intracerebral Hemorrhage in RatsMauren Assis Souza, Caroline Dalla Colletta Altermann, Alexandre dos Santos Martins et al.The present study shows the neuroprotective effect of green tea supplementation (GT; Camellia sinensis) in a model of Intracerebral Hemorrhage (ICH) in rats. ICH was induced by intra-striatum collagenase infusion in male Wistar rats. GT (400 mg Kg-1) was administered via gavage for 10 days after ICH. We assessed the effect of GT on neuromotor recovery and oxidative damage. Our … …Neuroscience International, Vol. 7, Issue 2 · 19 Mar 2017 · 8,598 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHippocampal Pyramidal Cell Degeneration and Changes in Creb Protein in Datura stramonium Treated RatsPeter Etim Ekanem, Dare S. Sunday, Sunday Abba, Amanuel TesfayDatura Stramonium (DS) is a tropical shrub which is available worldwide. It has various uses and is often used to increase the intoxication of certain beverages. The seeds of this plant are very toxic but are commonly smoked in like manner as tobacco. The present study investigated the potential harmful effects of DS on pyramidal cells and CREB protein in … …Neuroscience International, Vol. 6, Issue 2 · 17 Sep 2015 · 7,062 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFactors Those Up Regulate Klotho and Glutathione Peroxidase-1 Gene Expression Improve Renal Function in Rats with Acute Renal FailureFatma E. El-Gendey, Shabaan A. Hemeda, Gamal A. Sosa, Naglaa F. AlhusseiniAcute Renal Failure (ARF) has traditionally been defined as the abrupt and progressive loss of kidney functions resulting in the retention of urea and other nitrogenous waste products associated with interstitial inflammation, tubular injury and increasing Tumor Necrosis Factor (TNF). Mortality in patients with ARF remains high >50% in severely ill patients. Klotho gene is a new anti-aging gene. Genetic … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 15 Aug 2015 · 7,097 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePrenatal Ethanol Exposure Affects the Proliferation and Differentiation of the Osteoblasts from Newborn RatsIsabel Chaves Silva Carvalho, Dennia Perez de Andrade, Noala Vicensoto Moreira Milhan et al.Alcohol exerts teratogenic effects and its consumption during pregnancy may cause various alterations in the fetus, including deficit of bone development. The objective of this study was to evaluate the initial responses, on osteoblasts isolated from newborn rat calvaria, after prenatal ethanol exposure. Nine pregnant rats were divided into three groups according to the diet fed during pregnancy: Rats fed … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 14 Jul 2015 · 6,704 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAlbusite: A Novel Synthetic Gel for Promotion of Skin Wound Healing in RatsShahram Jahanabadi, Mohammad Yasin Karami, Shahram Paydar et al.The current study was performed to evaluate the effect of Albusite gel on the healing process of excisional wounds in diabetic and control rats. Fifty-two Sprague Dawley male rats were used to evaluate the effects of Albusite Gel (synthetic gel) on the healing of full-thickness skin wounds. The control group (n = 2 6) and study group (n = 26) … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 26 Jun 2015 · 7,040 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMicroscopic Study of the Lungs of Sprague-Dawley Rats from Various Ages of Postnatal and Aging PeriodsRia Margiana, Isabella Kurnia Liem, Jeanne Adiwinata PawitanPhysiological changes in postnatal and aging lung are associated with a variety of microscopic changes in the lung, especially the alveolar lung tissue, both in the interstitial and epithelial component. Interstitial tissue of the lung will increase in thickness that is supposed to be due to changes in fiber composition, particularly collagen. However, the exact changes are still under debate … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 13 Jun 2015 · 7,312 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHepatoprotective Effect of Opuntia Ficus-Indica Aqueous Extract against Carbon Tetrachloride-Induced Toxicity in RatsZouhir Djerrou, Zineb Maameri, Sihem Halmi et al.The present study was undertaken to evaluate the hepatoprotective activity of Opuntia ficus-indicaL. aqueous extract. About 24 Wistar male rats were divided randomly to 4 groups of 6 each. The 1st was given distilled water and served as normal control (CRL). The 2nd was intoxicated orally with carbon tetrachloride at a dose of 1.5 mL/kg each 72 h (CCl4 group) … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 2 Jun 2015 · 7,254 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Exercise Prior or After Ischemia on the Density of Neurons and Astrocytes in the Brain of RatsLaila Cristina Moreira Damázio, Raphael Teixeira Rocha Melo, Maira de Castro Lima et al.The aim of this study was to analyse the density of astrocytes and neurons in the motor areas of the cortex, striatum and hippocampus of rats that performed exercise before or after cerebral ischemia. A total of 36 Wistar rats were separated into two groups: One that was subjected to Middle Cerebral Artery Occlusion (MCAO) and the other that underwent … …Neuroscience International, Vol. 5, Issue 2 · 14 Jan 2015 · 7,345 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Combined Fenofibrate and Nicotinamide on Oxidative Stress and Inflammatory Cytokines Involved in Cisplatin-Induced Nephrotoxicity in RatsOmaima M. Abd Allah, Abeer A.I. Sharaf El-Din, Fouad El DebakeyCisplatin (Cis) is an anticancer drug, which is accompanied with major side effects including nephrotoxicity. The current study was performed to assess the possible prophylactic effects of fenofibrate (FEN), Nicotinamide (NAM) and their combination on oxidative stress and inflammatory cytokines associated with cisplatin-induced renal damage. Rats were randomly divided into seven groups (8 each) as follows; control group; FEN group … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 9 Jan 2015 · 7,128 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiochemical Efficacy of Nigella Sativa Oil and Metformin on Induced Diabetic Male RatsYassmina K. Mahmoud, Sherif Y. Saleh, Abd El Rehim A. El Ghannam, Ibrahim A. IbrahimThis study was carried out to investigate possible beneficial effects of Nigella sativa oil supplementation to diabetic rats. Fifty male Sprague-Dawley rats were randomly divided into five groups (n = 10/group) as follows: group I (normal control), group II (diabetic control), group III (diabetic rats treated with metformin), group IV (diabetic rats treated with metformin and Nigella sativa oil) and … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 7,898 accessesView PDFCite