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137 results for “immune system”
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Research ArticleOpen accessIn the abstractModulation of IFN-γ, IL-4 and IL-17 Cytokines is Related to Parasitemia Control in Mice Infected by Trypanosoma cruzi and Treated with BiotherapyFabiana Nabarro Ferraz, Franciele Karina da Veiga, Denise Lessa Aleixo et al.The study of biotherapies as an intervention in experimental models of infection is a possible means to understand the effects of these highly diluted medications. The present study evaluated the immunological and parasitological effects of biotherapies that were prepared from mouse serum that was uninfected (sarcode: BSNI13cH group) and chronically infected with the Y strain of T. cruzi (nosode: BSI13cH … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 30 Oct 2015 · 7,360 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,629 accessesView PDFCite
Research ArticleOpen accessIn the abstractCLINICAL EXPERIENCE OF CANCER IMMUNOTHERAPY INTEGRATED WITH OLEIC ACID COMPLEXED WITH DE-GLYCOSYLATED VITAMIN D BINDING PROTEINEmma Ward, Rodney Smith, Jacopo J.V. Branca et al.Proteins highly represented in milk such as α-lactalbumin and lactoferrin bind Oleic Acid (OA) to form complexes with selective anti-tumor activity. A protein present in milk, colostrum and blood, vitamin D binding protein is the precursor of a potent Macrophage Activating Factor (GcMAF) and in analogy with other OA-protein complexes, we proposed that OA-GcMAF could demonstrate a greater immunotherapeutic activity … …American Journal of Immunology, Vol. 10, Issue 1 · 8 Mar 2014 · 13,193 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Gc-Macrophage Activating Factor in Human Neurons; Implications for Treatment of Chronic Fatigue SyndromeRodney Smith, Lynda Thyer, Emma Ward et al.Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disease of multifactorial aetiology characterized by immune system dysfunction, widespread inflammation, multisystemic neuropathology and persistent pain. Given the central role of the immune system in the pathogenesis of the syndrome, we studied the effects of a potent modulator of the immune system in in vitro and in vivo models that could help … …American Journal of Immunology, Vol. 9, Issue 4 · 6 Nov 2013 · 10,991 accessesView PDFCite
Research ArticleOpen accessIn the abstractOdds to Quicken Reporting Already Delayed Cases: Acquired Immune Deficiency Syndrome Incidences are IllustratedRamalingam ShanmugamDelayed reporting in a medical system complicates efforts to estimate the number of cases that occurred in a time period. A case in point is the government’s difficulty to estimate the number of Acquired Immune Deficiency Syndrome (AIDS) cases. The reporting delays are not intentional but are ongoing due to changing Federal regulations or medical definitions of the case like … …International Journal of Research in Nursing, Vol. 4, Issue 1 · 1 Apr 2013 · 6,419 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnamnestic Immune Response Eight Years After Immunization of Primates with a Multivalent HIV-1 GP120 Variable Peptide VaccineRebecca Rivera, Kyung Hee Kang, David E. Anderson et al.Successful development of an effective HIV vaccine hasn’t occurred yet partly as a consequence of the antigenic variation deployed by HIV-1 to escape the immune system. Our laboratory is dedicated to develop a single peptide synthesis approach to create multivalent peptides representing hypervariable epitopes of the gp120 envelope glycoprotein of HIV-1. Our previous study showed that our HIV HECs are … …American Journal of Immunology, Vol. 9, Issue 1 · 13 Mar 2013 · 7,212 accessesView PDFCite
Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,029 accessesView PDFCite
Research ArticleOpen accessIn the abstractCell-Mediated Immune Responses in the Sea-Star Asterias rubens (Echinoderm)Michel LeclercCell-mediated immune responses occur in sea star system. In Asterias rubens it is said that B sea star lymphocytes and T sea star lymphocytes exist in the axial organ which can be considered as an ancestral lymphoid organ. In the same manner the origin of lymphocytes can be found in Invertebrates such as Echinodermal. …American Journal of Immunology, Vol. 8, Issue 4 · 29 Nov 2012 · 7,254 accessesView PDFCite
Research ArticleOpen accessIn the abstractPorcine Respiratory and Reproductive Syndrome Virus Vaccinology: A Review for Commercial VaccinesV. G. PapatsirosPorcine Reproductive and Respiratory Syndrome (PRRS) since its appearance in Europe in the early 1990’s has resulted in tremendous economic losses. Under field conditions vaccination is one of the most efficient strategies for the prevention and control of PRRS. The aim of this study is to perform the PRRSV vaccinology regarding current status of commercial vaccines in Europe. There are … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 4 · 5 Nov 2012 · 8,127 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Galphaq Containing Protein in Immune RegulationYuan Liu, Lu Gan, Guixiu ShiG proteins, one of the most important transmembrane signal transducers, contain four subfamilies. Gαq is the α subunit of Gq protein subfamily. The Gαq containing protein initially attracted attention for its physiological significance is in cardiovascular system. In recent years, its role in immune regulation has been indicated. Studies domenstrated that Gαq plays crucial role in regulating both innate and … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 7,421 accessesView PDFCite