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79 articles for “effective dose”
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Research ArticleOpen accessIn the abstractGamma Irradiation Synthesis and Influence the Optical and Thermal Properties of Cadmium Sulfide (CdS)/Poly (Vinyl Pyrolidone) NanocompositesShawkat Salameh Gasaymeh, Shahidan Radiman, Lee Yook Heng, Elias SaionProblem statement: Gamma irradiation has been successfully used to prepare a spherical cadmium sulfide CdS/Poly Vinylpyrolidone (PVP) quantum dots nanoparticles with enhancement of their optical band gap energy and thermal properties at room temperature and under ambient pressure. Sodium thiosulfate was used as a sulfur source in an aqueous solution. The formation of lower band gap energy of CdS/PVP nanoparticles … …American Journal of Applied Sciences, Vol. 7, Issue 4 · 30 Apr 2010 · 8,465 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Acute Administration of Artemisia Persia Extracts on Arterial Blood Pressure and Heart Rate in RatsFarzaneh Esmaeili, Gholamreza Sepehri, Ghollam-Reza Moshtaghi-Kashanian et al.Problem statement: Artemisia Persia (AP) used for its therapeutic effects in folk medicine whiles some species of Artemisia shown a hypotensive effect. To determine the cardiovascular effect of AP, we tested the pharmacological responses of aqueous and methanolic extracts of AP on blood pressure (BP) and Heart Rate (HR) of normotensive and ephedrine induced hypertensive rats using a tail-cuff computerized … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 7,659 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic Triggers for Intervention in Aging, Disease and TraumaJoan Smith SonnebornHormesis refers to the ability of a chemical or physical agent to condition the physiological state of an organism to tolerate stress with low doses of otherwise harmful agents. Evolutionary evidence shows that the survival and longevity of species hinge on their optimal ability to resist stress challenge. Hormesis is a potent strategy to stimulate latent repair processes to tolerate … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,898 accessesView PDFCite
Research ArticleOpen accessIn the abstractMethamphetamine Inhibits β-Chemokines and Co-Stimulatory Molecule Expression by Dendritic CellsMadhavan P.N. Nair, Jose W. Rodriguez, Irina M. Borodowsky et al.The US is currently experiencing a serious epidemic of methamphetamine (Meth) use entangled with HIV-1 infection. Blood monocyte derived dendritic cells (DC ) are the first line of defense against HIV-1 infection and are the initial target of HIV-1 in injection drug users. Chemokines are known to be HIV-1 suppressing molecules and are positively associated with non- progression of HIV … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,546 accessesView PDFCite
Research ArticleOpen accessIn the abstractInsertion of poly (ethylene glycol)-lipid reduces the liposome-encapsulated hemoglobininduced thrombocytopenic reactionVibhudutta Awasthi, Beth Goins, William T. PhillipsInteraction with platelets has been recognized as a concern in the development of liposome-encapsulated hemoglobin as an oxygen carrier. This reaction causes a significant drop in circulating platelets in a rapid and transient fashion. We studied the effect of lipid bilayer charge on the magnitude of drop in circulating platelets. We also investigated the effect of post-inserted PEG-lipid on this … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,382 accessesView PDFCite
Research ArticleOpen accessIn the abstractNew Bacterial Species Isolated from Malaysian Sea Cucumbers with Optimized Secreted Antibacterial ActivityAbd El-Aziem Farouk, Faizal Abd. Hamid Ghouse, B.H. RidzwanIn this study, several Malaysian sea cucumber species that have traditional medicine value were selected and from them, the native bacterial population was isolated. Optimization of growth was designed and all bacterial secretions were tested for antibacterial properties. 30 bacterial types were isolated and 7 types recorded moderate antibacterial activity against K. pneumoniae, S. marscens, P. aeruginosa and E. feacalis. … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 2 · 30 Jun 2007 · 8,847 accessesView PDFCite
Research ArticleOpen accessIn the abstractRapamycin Inhibits Cystogenesis by Cystic Epithelial Cells Derived from Human Autosomal Dominant Polycystic KidneysGerard Elberg, Teresa V. Lewis, Lijuan Chen, Martin A. TurmanAutosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders and carries a high health burden since it progresses to renal failure in half of the afflicted individuals by the 6th decade of life. Currently, there is no effective treatment to slow the progression of ADPKD. Rapamycin, a drug most commonly used as an immunosuppressive agent … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,105 accessesView PDFCite
Research ArticleOpen accessIn the abstractCPI-1189 Protects Against Dextran Sulfate Sodium-induced Colitis in MiceBeverley Greenwood-Van Meerveld, Karl R. TylerNitrone-related therapeutics (NRTs) represent a new class of small molecules potentially effective in the treatment of inflammatory bowel disease (IBD) by protecting cells from damage caused by excess inflammation and/or oxidative stress. The goal of this study was to determine the efficacy and potency of CPI-1189, a novel therapeutic agent, in dextran sulfate sodium (DSS)-induced colitis in mice. Mice received … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 6,716 accessesView PDFCite
Research ArticleOpen accessIn the abstractPotential of Rice Husk and Rice Husk Ash for Phenol Removal in Aqueous SystemsA. H. Mahvi, A. Maleki, A. EslamiThe potential of rice husk and rice husk ash for phenol adsorption from aqueous solution was studied. Batch kinetics and isotherm studies were carried out under varying experimental conditions of contact time, phenol concentration, adsorbent dose and pH. Adsorption equilibrium of rice husk and rice husk ash was reached within 6 hours for phenolic concentration 150-500 μg/L and 3 hours … …American Journal of Applied Sciences, Vol. 1, Issue 4 · 31 Dec 2004 · 10,177 accessesView PDFCite
Research ArticleOpen accessIn the abstractParacetamol: A Focus on DogsCharbel Fadel, Irene Sartini, Mario GiorgiParacetamol (APAP) is an aniline analgesic, antipyretic and non-narcotic. It is an essential drug, widely used in human medicine. In veterinary medicine it has an extra label use in many countries. It is used exclusively in some animals, including dogs. It has a mechanism of action similar to that of NSAIDs, as well as other unique characteristics. A variety of … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 4 · 2 Nov 2021 · 11,595 accessesView PDFCite