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Research ArticleOpen accessIn the abstractMethamphetamine Inhibits β-Chemokines and Co-Stimulatory Molecule Expression by Dendritic CellsMadhavan P.N. Nair, Jose W. Rodriguez, Irina M. Borodowsky et al.The US is currently experiencing a serious epidemic of methamphetamine (Meth) use entangled with HIV-1 infection. Blood monocyte derived dendritic cells (DC ) are the first line of defense against HIV-1 infection and are the initial target of HIV-1 in injection drug users. Chemokines are known to be HIV-1 suppressing molecules and are positively associated with non- progression of HIV … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,543 accessesView PDFCite
Research ArticleOpen accessIn the abstractInsertion of poly (ethylene glycol)-lipid reduces the liposome-encapsulated hemoglobininduced thrombocytopenic reactionVibhudutta Awasthi, Beth Goins, William T. PhillipsInteraction with platelets has been recognized as a concern in the development of liposome-encapsulated hemoglobin as an oxygen carrier. This reaction causes a significant drop in circulating platelets in a rapid and transient fashion. We studied the effect of lipid bilayer charge on the magnitude of drop in circulating platelets. We also investigated the effect of post-inserted PEG-lipid on this … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,377 accessesView PDFCite
Research ArticleOpen accessIn the abstractNew Bacterial Species Isolated from Malaysian Sea Cucumbers with Optimized Secreted Antibacterial ActivityAbd El-Aziem Farouk, Faizal Abd. Hamid Ghouse, B.H. RidzwanIn this study, several Malaysian sea cucumber species that have traditional medicine value were selected and from them, the native bacterial population was isolated. Optimization of growth was designed and all bacterial secretions were tested for antibacterial properties. 30 bacterial types were isolated and 7 types recorded moderate antibacterial activity against K. pneumoniae, S. marscens, P. aeruginosa and E. feacalis. … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 2 · 30 Jun 2007 · 8,841 accessesView PDFCite
Research ArticleOpen accessIn the abstractRapamycin Inhibits Cystogenesis by Cystic Epithelial Cells Derived from Human Autosomal Dominant Polycystic KidneysGerard Elberg, Teresa V. Lewis, Lijuan Chen, Martin A. TurmanAutosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders and carries a high health burden since it progresses to renal failure in half of the afflicted individuals by the 6th decade of life. Currently, there is no effective treatment to slow the progression of ADPKD. Rapamycin, a drug most commonly used as an immunosuppressive agent … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,101 accessesView PDFCite
Research ArticleOpen accessIn the abstractCPI-1189 Protects Against Dextran Sulfate Sodium-induced Colitis in MiceBeverley Greenwood-Van Meerveld, Karl R. TylerNitrone-related therapeutics (NRTs) represent a new class of small molecules potentially effective in the treatment of inflammatory bowel disease (IBD) by protecting cells from damage caused by excess inflammation and/or oxidative stress. The goal of this study was to determine the efficacy and potency of CPI-1189, a novel therapeutic agent, in dextran sulfate sodium (DSS)-induced colitis in mice. Mice received … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 6,713 accessesView PDFCite
Research ArticleOpen accessIn the abstractPotential of Rice Husk and Rice Husk Ash for Phenol Removal in Aqueous SystemsA. H. Mahvi, A. Maleki, A. EslamiThe potential of rice husk and rice husk ash for phenol adsorption from aqueous solution was studied. Batch kinetics and isotherm studies were carried out under varying experimental conditions of contact time, phenol concentration, adsorbent dose and pH. Adsorption equilibrium of rice husk and rice husk ash was reached within 6 hours for phenolic concentration 150-500 μg/L and 3 hours … …American Journal of Applied Sciences, Vol. 1, Issue 4 · 31 Dec 2004 · 10,171 accessesView PDFCite
Research ArticleOpen accessIn the abstractRoboBrew: The Fully Autonomous Coffee MachineAnthony Achkar, Maroun Hannoun, Rita Younes et al.Robotics has emerged in several domains in the current century. However, in the restoration field, mainly in coffee shops, applications are still limited. Therefore, RoboBrew presents a groundbreaking fully automated system poised to transform the restaurant and coffee industries into a new era. At its core, RoboBrew features an advanced coffee maker system designed to deliver exceptional performance. This system … …Journal of Mechatronics and Robotics, Vol. 8, Issue 1 · 1 Oct 2024 · 8,515 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of a Phytomineral Complex and an Enzyme Preparation on the Absorption of Nutrients and the Energy Balance of Calves' DietEvgeniia Erenko, Aleksandr Ovchinnikov, Marat Aubakirov et al.Cost-effective animal husbandry directly depends on the correct breeding of replacement young animals using diets corresponding to the feeding rate for all nutrition elements of the detailed system. Critical to these diets are biogenic elements, pivotal in enzymatic reactions and immune defense. However, specifics on enhancing nutrient absorption through dietary supplements remain underexplored, particularly in the context of calves' preweaning … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 12 Jun 2024 · 4,592 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Exposure of Pesticides to Honeybees: A Global Threat to Food SecurityHalima Sadia, Pratik Raj Karki, Mansura Afroz et al.The pivotal role of honeybees as global pollinators underscores their significance in ecological and agricultural systems. However, the beekeeping industry faces a significant challenge due to the improper utilization of pesticides, resulting in adverse effects on honeybee populations. This comprehensive review endeavors to investigate the toxicity of pesticides to honeybees, examining the various routes of exposure. Furthermore, it aims to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 20 Jan 2024 · 6,058 accessesView PDFCite
Research ArticleOpen accessIn the abstractParacetamol: A Focus on DogsCharbel Fadel, Irene Sartini, Mario GiorgiParacetamol (APAP) is an aniline analgesic, antipyretic and non-narcotic. It is an essential drug, widely used in human medicine. In veterinary medicine it has an extra label use in many countries. It is used exclusively in some animals, including dogs. It has a mechanism of action similar to that of NSAIDs, as well as other unique characteristics. A variety of … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 4 · 2 Nov 2021 · 11,585 accessesView PDFCite