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Research ArticleOpen accessIn the abstractThe Investigation of Organelle Genomes of Extra Nuclear Sunflower Mutants with Variegated PhenotypeIrina Dremuk, Nikolay Kozel, Mariya Logacheva et al.The comparative analysis of complete chloroplast and mitochondrial DNA sequences of the original inbred line 3629 and three extra nuclear mutant lines variegated-1, variegated-15, variegated-17, obtained by the N-nitroso-N-methylurea induced mutagenesis, was done. The studied mutant lines were presented two different phenotypes with diverse chlorophyll content: Pale/green mutant line variegated-17 with 1.8% relative (to 3629 line) chlorophyll content in mutant … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 24 Oct 2017 · 7,633 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
EditorialOpen accessIn the abstractThe Timeless Contribution of Rootstocks towards Successful Horticultural Farming: From Ancient Times to the Climate Change EraIoannis E. PapadakisGrafting is a horticultural practice by which living vegetative plant organs (root, stem and/or buds) of either the same genotype or, usually, different genotypes belonging to the same species, genus, subfamily and/or family, are tightly connected to each other to form a double-compound plant. In fact, it is a method of asexual (clonal-vegetative) propagation of plants. The basal part of … …American Journal of Agricultural and Biological Sciences, Vol. 11, Issue 4 · 16 Dec 2016 · 9,521 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe HCV Replicase InteractomeAntonio Mas, Pilar Clemente-Casares, Eugenio Ramírez, Rosario SabariegosViruses are obligate parasites and can only reproduce within host cells because they lack metabolic pathways to complete their replication cycles. Host factors required in viral replication are mainly those involved in lipid metabolism, cell cycle control and apoptosis, cell-to-cell interactions, immune system regulation, etc. Several inhibitors targeting viral polymerases have been designed. However, the rapid appearance of resistant mutants, … …Current Research in Virology, Vol. 5, Issue 1 · 27 Jul 2016 · 13,210 accessesView PDFCite
Research ArticleOpen accessIn the abstractGene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells of Patients with Systemic SclerosisSimin Almasi, Saeed Aslani, Hadi Poormoghim et al.The Toll-Like Receptor (TLR) family is appeared to be expressed in many cell types in the immune system and plays a role in the pathogenesis of various autoimmune diseases. The expression profile and role of TLRs in Systemic Sclerosis (SSc) have been partly explained. It is aimed through this investigation to evaluate the expression pattern of TLR 4 and 5 … …American Journal of Immunology, Vol. 12, Issue 1 · 17 Mar 2016 · 7,049 accessesView PDFCite
EditorialOpen accessIn the abstractCommentary-How do we Improve Training for Receptor Research?Marilee Ann BenoreThis issue of the American Journal of Biochemistry and Biotechnology features articles about receptor-ligand interactions that are critical to the wellbeing of all living organisms. The importance of the field of receptor research is supported by the large number of articles published in journals, the numerous specialty journals, the international conferences and the percentage of legal drugs on the market … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 8 Dec 2015 · 8,056 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Association of HLA Class II Alleles with the Response to Alfa-Interferon/Ribavirin Therapy in Chronic Hepatitis C PatientsAwny Aly Abol-Ez Gawish, Nahla Abd El-Hamid Mohammed, Rasha Adel Sayed Ahmed Hussein, Elsaid Galal El-BadrawyHuman Leucocyte Antigens (HLA) class II appears to play an important role in the individual’s immune response to viral infection. The present study was aimed at assessment of the relationship between HLA DRB1 alleles and the response to HCV combined therapy in Chronic Hepatitis C patients (CHC). We enrolled a total of 44 chronically infected HCV patients without Hepatitis B … …American Journal of Immunology, Vol. 11, Issue 3 · 12 Nov 2015 · 6,700 accessesView PDFCite
Research ArticleOpen accessIn the abstractMinimum Free Energy Based Evaluation of mRNAs Secondary Structures Constructed by 18 Clinically Significant Exonic Single Nucleotide Polymorphisms (SNPs) and Haplotypes of 5 Missense SNPs of RB1 GeneSarder Nasir Uddin, Apurba Majumder, Khandker Khaldun Islam et al.Clinically significant 18 Single Nucleotide Polymorphisms (SNPs) from exon regions of Retinoblastoma gene (RB1) were analyzed to find out the structural variations in mRNAs. Online bioinformatic tools i.e., Vienna RNA, RNAfold were used for secondary structure analysis of mRNAs. Predicted minimum Free Energy Change (MFE) was calculated for mRNAs structures. It has been observed that the average of predicted MFE … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 21 Oct 2015 · 8,556 accessesView PDFCite
Research ArticleOpen accessIn the abstractFactors Affecting the Response to Interferon Alpha Therapy in Egyptian HCV PatientsNaglaa F. Alhusseini, Fathy M. Serry, Ashraf A. Kadry, Heba KhairyHepatitis C Virus (HCV) infection is one of the main causes of chronic liver disease worldwide. Egypt has the highest prevalence of Hepatitis C Virus (HCV) in the world, estimated nationally at 14.7%. knowledge of the predictors of Sustained Viral Response (SVR) to Pegylated Interferon (PEG-INF) and Ribavirin (RBV) therapy in patients with chronic hepatitis C is crucial for selecting … …American Journal of Immunology, Vol. 11, Issue 3 · 30 Sep 2015 · 6,619 accessesView PDFCite
Research ArticleOpen accessIn the abstractReducing Redundancy of Codons through Total GraphNisha Gohain, Tazid Ali, Adil AkhtarIn this study some algebraic connections in genetic code is being discussed. The genetic code is the rule by which DNA stores the genetic information about formation of protein molecule. Based on the physico-chemical properties of four RNA (or DNA) bases, two orders in the base sets are obtained. This ordering allows us to define a ring structure on the … …Current Research in Bioinformatics, Vol. 4, Issue 1 · 25 Jun 2015 · 7,339 accessesView PDFCite