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342 results for “In-vitro”
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Research ArticleOpen accessEvery word in the titleAcid-Base Buffering Properties of Five Legumes and Selected Food in vitroMaher M. Al-Dabbas, Khalid Al-Ismail, Ruba Abu Taleb, Salam IbrahimProblem statement: in vitro acid-Buffering Capacity (BC) values of 5% (dry matter) aqueous homogenized suspension of five legumes (broad bean, lentils, chickpea, kidney bean and lupine) and of selected antacid home preparations (cow's milk, almond, peanut, licorice, carob and lettuce stem) were investigated within and among samples from their respective initial pH until pH was decreased to 1.5. BC was … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 2 · 21 Jun 2010 · 9,739 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleViability of Lactobacillus delbrueckii Under Human Gastrointestinal Conditions Simulated In VitroKarina Cruz Pacheco, Gustavo Valencia Del Toro, Fabian Robles Martinez, Enrique Duran-ParamoProblem statement: Lactobacillus delbrueckii subsp. bulgaricus is a lactic bacteria mostly used in the production of yoghurt and it has an important probiotic activity that brings benefits to the human body. However, the gastrointestinal tract has aggressive conditions, such as the acid pH in the stomach and the bile in the duodenum, that reduce the viability of this bacteria. Approach: … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 1 · 31 Mar 2010 · 9,112 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn vitro Growth and Inhibition Studies of Monosodium Urate Monohydrate Crystals by Different Herbal ExtractsBharat B. Parekh, Sonal R. Vasant, Kashmira P. Tank et al.Problem statement: A large number of people in the world have been suffering from gout for centuries. Gout is the term given to a metabolic condition in which the signs and symptoms results from the deposition of crystals of Monosodium Urate Monohydrate (MSUM) in various connective tissues. Approach: It was quite difficult to grow good quality large MSUM crystals because … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 10,218 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn Vitro Metabolism Studies of Polybrominated Diphenyl Ethers Using Rat and Human Liver MicrosomesShun Wen Cheng, Kathleen Randall, Anne T. KotchevarA number of studies have recently reported the bioaccumulation of the commonly used fire retardants, Polybrominated Diphenyl Ethers (PBDEs), in humans and wildlife. Exposure of animals to PBDEs has been shown to result in developmental neurological, reproductive abnormalities and the disruption of endocrine function. Thyroid hormone equilibria was also shown to be altered by PBDE exposure. There is evidence that … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 6,999 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComparative Permeation Studies between Scale Region of Shed Snake Skin and Human Skin In vitroAroonsri Priprem, Chidchanok Khamlert, Thaned Pongjanyakul et al.Scales of shed king cobra (Ophiophagus hannah) skin from the dorsal portions, (SSS) and human breast epidermis (HE) were used as barrier membranes for comparison in an in vitro drug permeation study of nine active compounds (MW range 150-300 g mol-1, pKa 3-10). Each compound, saturated in a donor solution at pH 4.0 or 5.6, permeated through the barrier membrane, … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 8,419 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNutrient Digestibility and Gas Production of Some Tropical Feeds Used in Ruminant Diets Estimated by the in vivo and in vitro Gas Production TechniquesPaya Hamid, Taghizadeh Akbar, Janmohammadi Hossein, Moghadam Gholam AliSome feedstuffs which used in ruminants diet (corn grain, soybean meal, wheat bran and alfalfa) were analyzed for chemical composition, apparent in vivo nutrient digestibility, in vitro fermentation gas production and metabolizable energy. Chemical composition of test feeds differed in nutrient contents. Initially apparent in vivo digestibility of alfalfa nutrients were obtained then digestibility of nutrients for the other test … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 4 · 31 Dec 2007 · 7,672 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCardiovascular Effect of Capparis spinosa Aqueous Extract. Part VI: in vitro Vasorelaxant EffectN. A. Zeggwagh, J. B. Michel, M. EddouksThe aim of this study was to investigate the in vitro vasorelaxanteffect of Capparis spinosa aqueous extract (CSAE) at a dose of 10 mg mL-1. Aortic rings isolated from normal wistar rats were used. The addition of CSAE during the plateau phase of contraction, induced by noradrenaline and KCl, produced a rapid relaxation. Incubation of aortic ring with CSAE during … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 3 · 30 Sep 2007 · 7,449 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHigh Concentrations of Glucose can Activate or Inhibit Human Erythrocyte Aminolevulinate Dehydratase in vitro Depending Exposure TimeJ. C. Soares, D. Gabriel, V. Folmer et al.Hyperglycemia can cause oxidative stress and inactivate susceptible enzymes. In the present investigation we examined whether short-term incubations (24 or 48 h) with high concentrations of glucose (10-200 mmol L-1) inhibit ALA-D from human erythrocytes. Incubations of erythrocytes for 24 h with glucose (10 up to 40 mmol L-1) resulted in an increase of δ-ALA-D activity (P<0,001). Incubations of erythrocytes … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,689 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,078 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSelective Lymphocyte Activation and Inhibition of In Vitro Tumor Cell Growth by Novel MorphinansRicardo Gomez-Flores, Kimberly R. Vietti, William J. Dunn et al.Opioids can suppress immune functions and increase susceptibility to developing cancer and infectious diseases. Recently, novel opioid compounds have been synthesized that lack immunosuppressive effects. We evaluated the effects of morphinans with substituted pyrimidine (methyl, phenyl, hydroxy, and amino groups) and pyrazole groups on in vitro rat thymic lymphocyte and splenic macrophage functions, and tumor cell growth. We observed that … …American Journal of Immunology, Vol. 2, Issue 1 · 5 Mar 2005 · 7,082 accessesView PDFCite