Author

J. B. Michel

Faculty of Medicine Xavier Bichat, France

3 articles in our journals

Articles where this person is an author, newest first. People are matched by their name as printed (no ORCID iD is recorded for them), not by name alone; search the name as text to find namesakes too.

Research ArticleOpen accessAcute Hypotensive and Diuretic Activities of Chamaemelum nobile Aqueous Extract in Normal RatsN. A. Zeggwagh, J. B. Michel, M. EddouksThis study aims to evaluate the effect of Chamaemelum nobile (Cn) intravenous injection on cardiovascular and renal function of normal rats. Intravenous bolus injection of Cn at the dose of 50, 100 and 200 mg kg-1, produced dose dependent reduction in arterial blood pressure (p<0.001). Significant reduction in heart frequency was observed after Cn injection at a dose of 100 … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 3 · 30 Sep 2007 · 7,119 accessesView PDF Cite

Research ArticleOpen accessCardiovascular Effect of Capparis spinosa Aqueous Extract. Part VI: in vitro Vasorelaxant EffectN. A. Zeggwagh, J. B. Michel, M. EddouksThe aim of this study was to investigate the in vitro vasorelaxanteffect of Capparis spinosa aqueous extract (CSAE) at a dose of 10 mg mL-1. Aortic rings isolated from normal wistar rats were used. The addition of CSAE during the plateau phase of contraction, induced by noradrenaline and KCl, produced a rapid relaxation. Incubation of aortic ring with CSAE during … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 3 · 30 Sep 2007 · 7,449 accessesView PDF Cite

Research ArticleOpen accessCardiovascular Effect of Capapris spinosa Aqueous Extract in Rats. Part II: Furosemide-like Effect of Capparis spinosa Aqueous Extract in Normal RatsN.A. Zeggwagh, J. B. Michel, T. Sulpice, T. M. EddouksThe purpose of this study was to examine the diuretic effect of the aqueous extract of Capparis spinosa (Cs) at a dose of 500 mg kg-1 h-1 in normal rats. The aqueous extract was administred intravenously and the diuresis was followed within four hours after starting the treatment. Intravenous administration of aqueous Cs extract produced a significant increase on diuresis … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 3 · 30 Sep 2007 · 7,199 accessesView PDF Cite