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Research ArticleOpen accessIn the abstractSynthesis, Ant Proliferative Activity and Docking Study of New Quercetin Derivatives against MDA-MB231 Breast Cancer Cell LinesReham Adnan Al-Anssari, Rita S. Elias, Shaker A.N. AljadaanMDA-MB231 is a very aggressive and invasive triple negative breast cancer, which present with limited treatment options. Unlike other breast cancer types, it is characterized by absence of hormonal receptors of estrogen, progesterone as well as human epidermal growth factor receptor 2, rendering it unsuitable for hormonal therapy and a perfect candidate for chemotherapy. Quercetin is a common natural flavonoid … …American Journal of Applied Sciences, Vol. 16, Issue 5 · 26 Jun 2019 · 8,790 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Vascular Endothelial Growth Factor (VEGF) on Dental Pulp Stem Cells (DPSC)Eric Mullins, Cale Forgues, Karl KingsleyDental Pulp Stem Cells (DPSCs) are non-embryonic, mesenchymal stem cells that may have significant potential for therapeutic and regenerative biomedical applications. Studies of DPSC differentiation have demonstrated the potential to form many tissue types, including neural, osteogenic and vascular precursors using cytokines and growth factors, such as Vascular Endothelial Growth Factor (VEGF). Eight previously isolated Dental Pulp Stem Cell (DPSC) … …Current Research in Medicine, Vol. 9, Issue 1 · 1 Jun 2019 · 13,831 accessesView PDFCite
Research ArticleOpen accessIn the abstractCytotoxic Activity of Tinospora crispa Crude Extracts (Stem) Against K562 Human Leukemia CellsNormah Awang, Haziratul Iffah Ruzali, Rapidah Mohamad et al.Tinospora crispa (T. crispa) is traditionally used as an herbal medicine for treatment of gout and is an analgesic, anti-inflammatory and antihyperuricemic agent. Cytotoxicity of hexane, dichloromethane, ethanol and aqueous extracts of T. crispa stem against K562 cells was assessed. Crude extracts of T. crispa stem were obtained by sonication and maceration methods. T. crispa stem powder was macerated and … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 11 May 2019 · 7,870 accessesView PDFCite
Research ArticleOpen accessIn the abstractTrilobatin Possesses Protective Potentials on H2O2-Induced HepG2 Cells by Suppressing Oxidative Stress: Involvement of Nrf2/Keap1 Signal PathwayYuhan Zhai, Yuqing Zhang, Yaping Li et al.Trilobatin, a natural dihydrochalcone compound, possesses various biological activities. However, few investigations have been carried out on the mechanisms of trilobatin against oxidative stress. To comprehend the effects and mechanism of trilobatin on oxidative stress after hepatic injury, H2O2-induced HepG2 cells were used in this research. The results indicated that trilobatin enhanced the viability and improved the apoptosis morphology of … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 22 Dec 2023 · 5,087 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of the Biological Preparation Phytop 8.67 on the Quality and Yield of Rice in Saline SoilsNurzhan Ybraikozha, Asset Тоktamysov, Elvira Sagindykova et al.Phytop 8.67 is a modern biological multifunctional preparation that has a complex effect on cultivated plants, harmful organisms, and soil. The study aimed to evaluate the effect of the biological preparation Phytop 8.67 on increasing yields and improving the quality of rice grains. Rice of the Marzhan variety growing on meadow/marsh rice soils was studied. The use of phytop 8.67 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 3 Nov 2023 · 5,330 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Detection of Endobacteria in Rhizopus spp.Ratna Noviyanti, Gayuh Rahayu, Rida Oktorida KhastiniRhizopus spp. are commonly used in bio-industrial processes such as manufacturing traditional fermented foods. However, one species, R. microsporus has been reported to contain toxin-producing endobacteria. Therefore, it is essential to evaluate the Rhizopus strains' safety before application as tempe inoculum. The study aimed to detect the presence of endobacteria from seven strains of Rhizopus spp. isolated from Tempe and … …OnLine Journal of Biological Sciences, Vol. 23, Issue 3 · 24 Jun 2023 · 5,331 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Japanese Quail Egg-Yolk Extender in Cryopreservation of Cockerel SemenRantloko Rolly Maapola, Khathutshelo Agree Nephawe, Tshimangadzo Lucky Nedambale et al.The purpose of this study was to examine the effects of quail egg yolk extenders in the cryopreservation of cockerel semen. Ten Venda cockerels were chosen randomly and semen was collected twice a week with a two-day rest period using an abdominal massage technique. Immediately following semen collection, semen samples were evaluated for microscopic parameters (sperm cell motility, viability, morphology, … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 1 · 25 Mar 2023 · 5,638 accessesView PDFCite
Research ArticleOpen accessIn the abstractHibiscus Flower Extract and Niacinamide Show Enhanced Whitening Effects in Mouse Melanoma Cells (B16F10)Jae Eun Choi, Tae Su Jang, Jung Min Park et al.Melanoma, a type of cancer that most often occurs on skin exposed to UV rays, is becoming increasingly common. Recent research has focused actively on using natural products. The goal of this study was to compare the melanin-inhibitory effects of Hibiscus (Hibiscus sabdariffa L.) flower Extract (HE) and Niacinamide (NA), a functional ingredient with whitening effects, on melanoma cells. The … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 9 Feb 2023 · 7,226 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect Administration of Omega-3, Omega-6 and Synthetic Cholesterol on Reproductive Characteristic of Male Quail (Coturnix coturnix japonica)Abyadul Fitriyah, Supriyono, IsyaturriyadhahThe bird is one of the most important sources of animal protein for people and smallholders in developing countries. However, it is also important to look at their reproductive activity to maintain a sustainable population. Omega-3, omega-6 fatty acid and synthetic cholesterol may improve reproductive characteristics in animals including quail. Several treatments can be used to improve the quality of … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 4 · 7 Nov 2018 · 7,551 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Lactobacillus Plantarum and Bacterial Peptidoglycan on the Growth of Mouse Tumors in vivo and in vitroArpa Aintablian, Dalal F. Jaber, Mary Ann Jallad, Alexander M. AbdelnoorSome members of the microbiota have been shown to be effective strategies for inhibiting tumor growth through stimulation of host anti-tumor immune responses. Anti-tumor immune effects were observed when Lactobacillus plantarum (Lp), a member of the gut microbiota, was used to treat colorectal cancer in mice. Moreover, constituents of bacteria, including peptidoglycan (PG), have been shown to exhibit tumoricidal effects. … …American Journal of Immunology, Vol. 13, Issue 3 · 23 Sep 2017 · 8,451 accessesView PDFCite