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228 results for “toxicity”
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Research ArticleOpen accessEvery word in the titleEffect of Chromium(VI) on Serum Iron and Removal of its Toxicity by Combining Deferasirox and Deferiprone Chelators in RatsS. Jamil A. Fatemi, Marzieh Iranmanesh, Faezeh Dahooee BaloochThe present research is aimed to characterize the potential efficiency of two chelators after chromium(VI) administration for 60 days following two doses of 15 and 30 mg kg-1 chromium(VI) per body weight daily to male rats. However, the hypothesis that the two chelators might be more efficient as combined therapy than as single therapy in removing chromium(VI) from bood serum … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 30 Oct 2013 · 7,152 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleToxicity of Zinc Oxide Nanoparticles in Lung Tissue After Repeated Oral AdministrationAtaollah Shokouhian, Saman Soheili, Saeed Moradhaseli et al.Pathological experiments should be considered following oral administration of ZnO. Effect of different doses of ZnO nanoparticle on LDH in oral method showed significant differences in control group (p<0.05) at high dose. Levels of IgG, TNF-α and IL-6 also elevated after administration of ZnO. The level of GSH decreased significantly. Lung damages included hyperemia and bleeding, atelectasis, light emphysema, pribronchiolitis, … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 21 Oct 2013 · 7,703 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAroclor 1254 Toxicity to Mice Liver Membrane AtpasesShweta Pathak, Rahul KunduPresent communication reports the sub-acute dose and exposure duration dependent effects of Aroclor 1254 on total, Na+, K+, Ca++ and Mg++-ATPases of the mouse liver cells. The study tests two hypotheses, (a) whether the sublethal dose or the exposure duration dependent in vivo exposure of hydrophobic PCB (Aroclor 1254) affects the hydrophilic membrane-bound ion dependent ATPases of the liver cells … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 6,791 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluating Toxicity of Extracted Destruxin from Metarhizium Anisopliae Against Citrus Leafminer, Phyllocnistis citrellaM. Mohammadi Sharif, A. R. Hadizadeh, M.A. Tajick GhanbaryProblem statement: The fungus, Metarhizium anisopliae (Metschnikoff) Sorokin produces some cyclic peptide toxins, destruxins, which exhibit a variety of insecticidal actions. Citrus leafminer, Phyllocnistis citrella Stainton, is a major pest of young citrus trees; therefore its effective and safe control is a important issue. Approach: Five isolates of M. anisopliae were inoculated in Potato Dextrose Broth (PDB) mediums. Destruxin was … …American Journal of Environmental Sciences, Vol. 6, Issue 4 · 31 Aug 2010 · 7,251 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStudy of the Anatomical, Morphological, and Phytochemical Properties of Conium maculatum L.Aigerim Abdygalieva, Meruyert Sakenovna Kurmanbayeva, Dina Karabalayeva et al.The aim of this study is to identify the characteristic anatomical and morphological features and analyze the phytochemical composition of Conium maculatum L. growing in the Almaty region, in order to assess the quality of the medicinal plant raw material. Detailed anatomical investigations were conducted, including microscopy of various plant organs (leaves, stems, and roots), as well as phytochemical analysis … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 23 Jun 2025 · 3,406 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe interplay between Cadmium and Zinc Induced Developmental Perturbations and Apoptosis in Daphnia MagnaNaima Hamid, Siti Nur Airina Binti Ibrahim et al.Assessing combined toxicity provides a realistic and comprehensive approach to determining toxicological effects in aquatic species under environmentally relevant conditions. This study was conducted to understand the effects of single and combined metal mixtures on freshwater flea and Daphnia magna. Environmentally Relevant Concentrations (ERCs) of Cadmium (Cd) and Zinc (Zn) at a low dose (10μg/L) and high dose (30 μg/L) … …American Journal of Environmental Sciences, Vol. 21, Issue 1 · 11 Jun 2025 · 6,015 accessesView PDFCite
Case ReportOpen accessIn the keywordsSurvival Following Severe Paraquat Poisoning a Case Study from the Andaman and Nicobar IslandsShiv Shankar Singh, Colin Sanchez, Prasan Kumar PandaParaquat poisoning continues to pose a significant public health challenge in the Andaman and Nicobar Islands, largely due to its alarmingly high mortality rate. In this report, we present the case of a 39-year-old male farmer who ingested 30 mL of paraquat with the intent of suicide. Initially, the patient underwent prompt gastric lavage and exhibited relative stability. Upon admission, … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 22 Jan 2025 · 10,605 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHeavy Metals Content and Ecotoxicity of Sediments from the Congo RiverDidier Makonko Mabidi, Honoré Manyingu Mutwejile, Georgette Ngakiama Beni Ngweme et al.This research aimed to quantify the contamination of Congo River sediments by heavy metals and to evaluate their ecotoxicological effects in the municipalities of Maluku, Gombe, and Kinsuka, Kinshasa Province. Metal concentrations in sediments reached 340 mg kg-1 for Cr, 310 mg kg-1 for Cu, 826 mg kg-1 for Zn, 63 mg kg-1 for as, 1.9 mg kg-1 for Cd, … …American Journal of Environmental Sciences, Vol. 20, Issue 1 · 9 Nov 2024 · 6,046 accessesView PDFCite
Research ArticleOpen accessIn the keywordsImpact of Coriander Seeds Extract Against Thyroidectomy Induced Testicular Damage and DNA Replication in Male RatsAzhar Azher Alankooshi, Ahmed F. Hasan et al.An important target organ for thyroid hormone activity is the testis and hypo or hyperthyroidism causes noticeable alterations in testicular function. This study aimed to investigate the therapeutic effect of Coriander Seeds Extract (CSE) against thyroidectomy induced toxicity, oxidative stress, injury, and proliferation in male testes rats. 40 male rats were equally divided into 4 groups [Gp1, control; Gp2, CSE; … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 3 Apr 2023 · 6,611 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of two Different Permitting and Combination of Cryoprotectants on Cattle Oocytes Maturation Rate Following Brilliant Cresyl Blue ExposureMasindi Lottus Mphaphathi, Hester Adri O'Neill, Tshimangadzo Lucky NedambaleThe objectives of this study were to elucidate the toxicity of Dimethyl sulfoxide (DMSO), Ethylene glycol (EG), and the combination of both permitting cryoprotectants (CPAs) to cattle oocytes and the effectiveness of Brilliant cresyl blue (BCB) on immature oocytes pre-selection. Cattle ovaries were collected from the local slaughterhouse and transported within 2 hours of slaughter. The oocytes were exposed to … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 2 · 6 May 2022 · 6,201 accessesView PDFCite