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98 results for “protein structure”
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Research ArticleOpen accessIn the abstractModeling and Molecular Docking Studies on Rnase Aspergillus niger and Leishmania donovani Actin: Antileishmanial ActivityRavi Kumar Gundampati, Shraddha Sahu, Kirti Shila Sonkar et al.A.niger Rnase was designed from ACTBIND (PDB ID: 3D3Z). Yeast actin-human gelsolin segment 1 complex (PDB ID: 1YAG) was used as template for L. donovani actin protein for 3D model in Modeller9v8. These models were testified by PROCHECK, ERRAT, WHAT-IF, PROSA2003 and VERIFY-3D. All evidences suggest that the geometric quality of the backbone conformation, energy profile, residue interaction and contact … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,527 accessesView PDFCite
Research ArticleOpen accessIn the abstractHomology Modeling of Buffalo (Bubalus bubalis) Interferon-Tau ProteinIndu Joshi, Sunil Kumar, Arminder Kaur et al.Interferon-tau (IFNt) contributes towards maternal recognition of pregnancy in ruminants (like, cattle, buffalo, goat, giraffe). IFNt has been extensively studied in most of the ruminants except for buffalo Bubalus bubalis). The present study has been undertaken to predict the secondary structure of Interferon-tau in buffalo. The available amino acid sequence of bubaline IFNt (sequence database of SwissProt) was subjected to … …Current Research in Bioinformatics, Vol. 1, Issue 2 · 17 Apr 2013 · 7,003 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Pharmacological Targets Combining Docking and Molecular Dynamics SimulationsIlizaliturri-Flores Ian, Rosas-Trigueros Jorge Luis, Carrillo-Vazquez Jonathan Pablo et al.Studies that include both experimental data and computational simulations (in silico) have increased in number because the techniques are complementary. In silico methodologies are currently an essential component of drug design; moreover, identification and optimization of the best ligand based on the structures of biomolecules are common scientific challenges. Geometric structural properties of biomolecules explain their behavior and interactions and … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 21 Mar 2013 · 8,128 accessesView PDFCite
Research ArticleOpen accessIn the abstractDIFFERENT APPROACHES TO CRYSTALLIZATION OF MEMBRANE PROTEINSPrakash G. Doiphode, Vivek Pratap SinghCrystallography is more like an art than science. Crystallizing membrane proteins are a big challenge; membrane proteins are present in the cell membrane and serve as cell support. The most important feature of membrane protein is that it contains both hydrophobic and hydrophilic regions on its surface. They are generally much more difficult to study than soluble proteins. The problem … …OnLine Journal of Biological Sciences, Vol. 12, Issue 3 · 18 Dec 2012 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Characterization of Inflammatory and Structural Markers within the Rumen Epithelium During Grain-Induced Ruminal Acidosis in Lactating Dairy CattleL. Dionissopoulos, M. A. Steele, O. AlZahal et al.The objective of this study was to characterize the mRNA and protein expression of inflammatory and structural genes in the rumen epithelium during grain-induced ruminal acidosis in lactating dairy cattle. A total of 16 rumen-fistulated, lactating Holstein dairy cattle (618±35 kg of body weight, 221±32 days in milk) were used in a randomized complete block design study. All cattle were … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 3 · 19 Sep 2012 · 8,035 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Enterobacterial Repetitive Intergenic Consensus PCR in Detecting Target(s) of Hapalindole-T, From a Cyanobacterium, in Escherichia Coli: In Silico ValidationManoj K. Tripathi, Maheep Kumar, Vinay K. Singh et al.Problem statement: Identification of newer biomolecule as well as targets are a rising concern because of increasing drug resistance in bacteria. We have isolated a broad spectrum antibiotic biomolecule Hapalindole-T from a cyanobacterium, Fisherella sp. growing on local Azadirachta indica tree bark. A model bacterium E. coli was screened spontaneously for Hap-T resistance. These resistant strains of E. coli were … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 3 Mar 2012 · 13,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractCloning of the Endoglucanase Gene from a Bacillus amyloliquefaciens PSM 3.1 in Escherichia coli Revealed Catalytic Triad Residues Thr-His-GluZeily Nurachman, Sari Dewi Kurniasih, Ferra Puspitawati et al.Problem statement: An Indonesian marine bacterial isolate, Bacillus amyloliquefaciens PSM 3.1 was isolated for hydrolyzing cellulose. A 1500-bp nucleotide fragment was amplified from the chromosomal DNA by the use of primers directed against the conserved sequence of Bacilli endoglucanase genes obtained from GenBank. Approach: The fragment was cloned and expressed in Escherichia coli. Results: The endoglucanase gene (eglII gene) had … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 4 · 31 Dec 2010 · 9,724 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Silico Analysis of Envelope Dengue Virus-2 and Envelope Dengue Virus-3 Protein as the Backbone of Dengue Virus Tetravalent Vaccine by Using Homology Modeling MethodUsman Sumo Friend Tambunan, Arli Aditya Parikesit, Hendra et al.Problem statement: Dengue fever, which was caused by Dengue virus infection, had became a major public health problem in the tropic and subtropical countries. Dengue virus (DENV) had four serotypes (DENV-1, DENV-2, DENV-3 and DENV-4), based on their immunogenic in the human body. Preventive measure will be necessary to decrease the prevalence of dengue fever, by developing modern vaccine. Approach: … …OnLine Journal of Biological Sciences, Vol. 9, Issue 1 · 3 Sep 2010 · 9,265 accessesView PDFCite
Research ArticleOpen accessIn the abstractNutritional Value of the Maize Stalk Borer and American Bollworm as Unconventional Protein SourcesA.E. Ghaly, F.N. AlkoaikProblem statement: The maize stalk borer and American bollworm were grown in an artificial media to evaluate their potential as human food sources. Approach: Both cultures were started from moths and the life cycle and culture structures were evaluated. Results: The larvae of both insects reached maximum weight and maximum length at the same time. The growth rate of the … …American Journal of Applied Sciences, Vol. 7, Issue 1 · 31 Jan 2010 · 8,088 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Use of Insects as Human Food in ZambiaA.E. GhalyProblem statement: The life cycle and culture structure of two commonly eaten worms in Zambia (Isoberlinia paniculata and Miombo/Mopani) were evaluated. The worms were grown on an artificial medium to evaluate the potential of producing them on a commercial scale. Approach: An interesting characteristic of the worms studied was that they reached their maximum weight and maximum length at the … …OnLine Journal of Biological Sciences, Vol. 9, Issue 4 · 31 Dec 2009 · 8,701 accessesView PDFCite