Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

147 articles for “chromatography”
Set a search alert
Research ArticleOpen accessIn the abstractIntegrated Monitoring of Endocrine-Disrupting Chemicals: Analytical Chemistry and Biological Assessment ApproachesChangjin Li, Jing Huo, Zijun Dou et al.Endocrine-Disrupting Chemicals (EDCs) in aquatic environments pose significant threats to ecosystems and human health. These compounds interfere with hormonal regulation at low concentrations and have non-monotonic dose-response relationships, posing challenges to conventional risk assessment. This review systematically compares current EDC monitoring methods, including instrumental chemical analysis and receptor-based biological detection systems, to evaluate sensitivity thresholds, sample throughput, and mechanistic selectivity … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 3 Jul 2026 · 1,089 accessesView PDFCite
Research ArticleOpen accessIn the abstractPurification, Structural Characterization and Anti-Aging and Stress Activities of Cordyceps Mycelium Polysaccharides from Paecilomyces HepialiXiaokang Hu, Huixiu Ma, Guicai Chen et al.This study identified and characterized the bioactive polysaccharide components from Cordyceps mycelium powder (CMP) derived from Paecilomyces hepiali, evaluating their anti-aging and stress-protective activities. Initial screening using Drosophila melanogaster revealed that crude Cordyceps polysaccharides (CCP) exhibited comparable effects to CMP and Cordyceps aqueous extracts (CAE) on natural lifespan and UV stress resistance, suggesting CCP as the primary bioactive component. CCP … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 16 Feb 2026 · 1,702 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of Hydrodistillation Extraction by Response Surface Methodology and Evaluation of the Antioxidant and Antimicrobial Activities of Essential Oils from Phragmites communis (Cav) TrinXin-Tong Zou, Hong-Yuan Ma, Yu-He Li et al.The principal objectives of this study encompass three distinct aspects: firstly, to streamline the extraction process of Phragmites communis (Cav) Trin essential oil; secondly, to systematically analyze the essential oil’s chemical composition; and finally, to evaluate biological activity. Through the system optimization experiment, the optimal extraction process was determined: the crushing size was set to 10 mesh, the total solid-liquid … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 6 Jan 2026 · 2,320 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Characterization of Chemical Constituents, Cytotoxicity, Antibacterial and Antioxidant Activity of the Compounds from Leptadenia hastata Roots Extract ByIsaac John Umaru, Hauwa A. UmaruThe aim of this work was to extract, isolate and characterise the chemical constituent from Leptadenia hastata roots. Fresh roots were washed and dried and was subjected to sequential maceration in polar and non-polar solvents. And introduced into rotary evaporator to concentrate the extract. Isolated compound was subjected to Thin Layer Chromatography and spectral analysis such as column and UV-Visible … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 24 Dec 2019 · 7,961 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of 1-Deoxynojirimycin Content and Phytochemical Profiles from Young and Mature Mulberry Leaves of Morus Spp.Yasinta Ratna Esti Wulandari, Vivitri Dewi Prasasty, Adrianus Rio, Cindy GeniolaMulberry leaves have been known to be rich in 1-Deoxynojirimycin (DNJ) which inhibits postprandial hyperglycemia by inhibiting α-glucosidase in the small intestine and thereby reducing the breakdown of starch and other complex sugar into glucose. Mulberry leaf extract also contains many other bioactive compounds and phytochemicals. They are very effective in supporting blood sugar levels and balancing cholesterol and triglycerides. … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 3 Jun 2019 · 11,081 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Phytochemical Analysis of Hydrodistilled Essential Oils of Scots Pine (Pinus Sylvestris L.) Needles From Central KazakhstanKuralay Tuleshova, Margarita Ishmuratova, Asanali Aynabayev et al.This study presents a detailed phytochemical investigation of hydrodistilled essential oils extracted from the needles of Pinus sylvestris (Scots pine), collected from fifteen natural populations located in the Karaganda and Ulytau regions of Central Kazakhstan. The extraction was performed using hydrodistillation with hexane as a co-solvent, and the chemical composition of the oils was subsequently analyzed using gas chromatography–mass spectrometry … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 28 Nov 2025 · 2,700 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhytochemical Composition, Antibacterial, and Antioxidant Properties of Foeniculum vulgare Essential OilSaif M. Dmour, Saqr Abushattal, Sultan Ayesh Mohammed Saghir et al.This study intended to inspect the phytochemical composition and bioactivity of Fennel (Foeniculum vulgare) Seed Essential Oil (FSEO) from Jordan. The EO was extracted via hydrodistillation from air-dried samples with 4.42% (v/w) yield. Twenty compounds, constituting around 98.5% of the EO were identified using Gas Chromatography-Mass Spectrometry (GC-MS). Estragole (47.15%) and Anethole (36.2%), appeared as predominant oxygenated monoterpenes compounds in … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 1 Aug 2025 · 4,640 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeparation, Purification and Anti-aging Activity of Tobacco PolysaccharidesMengyue Huang, Jingwu Song, Shuaishuai Chang et al.To separate tobacco polysaccharides and investigate their antioxidant and anti-aging properties, crude tobacco polysaccharides were extracted from raw tobacco using hot water, followed by purification through DEAE-52 cellulose column chromatography. The molecular weight and monosaccharide composition of the isolated polysaccharides were analyzed using HPGPC and HPLC. The antioxidant activities of these tobacco polysaccharides were tested using DPPH, ABTS, hydroxyl radicals … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 15 Jan 2025 · 5,108 accessesView PDFCite
Research ArticleOpen accessIn the abstractLarvicidal Activity of Bruceine A against Aedes aegypti and Toxicity on Vero CellsDwi Sutiningsih, Mustofa, Tri Baskoro Tunggul Satoto, Edhi MartonoVector control is still based on the use of chemical insecticides, which can cause death of nontarget animals, pollution and the emergence of vector resistance. This study aims to assess the larvicidal activity of bruceine A against larvae of Aedes aegypti and its cytotoxic activity against Vero cells. Extraction and isolation of bruceine A from the seeds of Brucea javanica … …OnLine Journal of Biological Sciences, Vol. 18, Issue 3 · 4 Sep 2018 · 7,915 accessesView PDFCite
Research ArticleOpen accessIn the abstractNovel LC-MS/MS Method for CJ-023423 (Grapiprant) Determination in Rabbit PlasmaElena Baralla, Virginia De Vito, Maria Vittoria Varoni et al.Grapiprant is a new anti-inflammatory drug that preferentially targets the EP4 receptor of prostaglandin E2 limiting the wide range of adverse effects caused by the classical non steroideal anti-inflammatory drugs. The aim of this study was to develop and validate a new, simple, sensitive and rapid Liquid Chromatography tandem Mass Spectrometry method (LC-MS/MS) in order to quantify this novel drug … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 2 · 24 May 2018 · 7,995 accessesView PDFCite