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60 results for “Vaccination”
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Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractKEY PARAMETERS OF MEASLES VIRUS PRODUCTION FOR ONCOLYTIC VIROTHERAPYK. Weiss, D. Salzig, M. D. Mühlebach et al.Attenuated measles virus has revealed selective tumor cell killing and is currently tested in clinical trials for the therapy of cancer patients. The amount of infectious particles per dose needed for oncolytic therapy can be more than a million times higher compared to vaccination. This requires highly effective production processes which guarantee the measles virus quantities needed for its use … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 9,785 accessesView PDFCite
Research ArticleOpen accessIn the abstractLevamisole Enhances Cell-Mediated Immune Responses and Reduces Shedding of H9N2 Avian Influenza Virus in Japanese Quails (Coturnix coturnix japonica)Tahoora Shomali, Najmeh Mosleh, Arash AlaeddiniProblem statement: Regarding the role of Japanese quails (Coturnix coturnix japonica) in reassortment and spreading of avian influenza (AI) viruses and inadequate protection of vaccination in this species, the present study aimed to evaluate the effect of levamisole as an immunomodulatory agent on cell-mediated immunity (CMI), antibody responses and shedding of H9N2 AI virus in experimentally infected quails. Approach: On … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 6 Mar 2012 · 7,651 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment of Transgenic Maize using Immature Embryos of HiII Genotype as a Vaccine CandidateHyun A. Kim, Suk Yoon Kwon, Han Sang Yoo et al.Problem statement: Plant-based vaccines posses some advantages over other types of vaccine biotechnology such as safety, low cost of mass vaccination programs and wider use of vaccines for veterinary medicine. These study was undertaken to develop the transgenic maize as edible vaccine candidate for animals. Approach: The immature embryos of HiII genotype were inoculated with A. tumefaciens strain C58C1 containing … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 1 · 5 Mar 2012 · 7,567 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunologic Response to Hepatitis B Vaccine in Health Care Workers: A Screening Program and Evaluation of Some Host-Related Factors RoleMojtaba Varshochi, Roghayyeh MahmodianProblem statement: To evaluation the immunologic response to hepatitis B vaccine in health care’s workers and effects of host-related factors? Approach: In a cross sectional descriptive analytic study carried out on the medical staff of Tabriz Shahid Madani Hospital in 2009-2010, we evaluated the immunologic response of the staff to vaccination against Hepatitis B and factors affecting it. Results: The … …American Journal of Immunology, Vol. 7, Issue 1 · 17 Sep 2011 · 8,962 accessesView PDFCite
Research ArticleOpen accessIn the abstractFormulation and Evaluation of a Novel Needle-Free Hepatitis B Surface Antigen Delivery SystemC. D. Licy, K. Premalatha, Annie Shirwaikar, Arun ShirwaikarProblem statement: Hepatitis B is a major public health problem, killing 1-2 million people annually, despite the introduction of an effective vaccine in 1982. Approximately 400 million persons worldwide have chronic hepatitis B. This is due to problems associated with vaccine delivery, stability and cost. Hence the present challenge in Vaccinology is to develop safer, cheaper and easy-to-deliver forms of … …Current Research in Medicine, Vol. 1, Issue 2 · 30 Oct 2010 · 6,819 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of Salmonella enteritidis Outer Membrane Proteins and Lipopolysaccharide Profiles with the Detection of Immune Dominant ProteinsA. Maripandi, Ali A. Al-SalamahProblem statement: Salmonella infection is a serious medical and veterinary problem world-wide and causes great concern in the human health and food safety. Salmonella enteritidis outer membrane proteins and lipopolysaccharide play important role in the virulence and immunological properties of bacteria. Prophylaxis of enterobacterial infection has proven difficult to achieve. Vaccination is an effective tool for the prevention of Salmonella … …American Journal of Immunology, Vol. 6, Issue 1 · 21 Jun 2010 · 9,147 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of a DNA Vaccine for Immunocontraceptive Potential Against Zona Pellucida Glycoproteins in CattleC.A. Foley, S.M. Boyle, R.E. Pearson, F.C. GwazdauskasHolstein cows were administered zona pellucida (ZP) DNA vaccine and used to determine the potential of recombinant rabbit ZP glycoproteins (rZP) as immunocontraceptive antigens. Zona pellucida proteins were purified and quantified. Cows were assigned to one of four treatment groups in which plasmids encoding rabbit ZP proteins were administered, i.d., using a gene gun (ZP55, n=2; ZP75, n=2; Hep55, n=2; … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 1 · 31 Mar 2007 · 6,888 accessesView PDFCite
Research ArticleOpen accessIn the abstractCOVID-19 in the Era of Artificial Intelligence: Existing Technologies and A Strategic Model for Mitigating Future PandemicsBandar Mzel AlshammariPandemics have existed since the existence of life and will continue as life continues. Throughout many of the previous pandemics, what played a major role in decreasing their severity is how we mitigated and controlled them. The main reason for this is the time it takes for treatments and vaccinations to be developed, which usually takes a long time. Therefore, … …Journal of Computer Science, Vol. 20, Issue 5 · 20 Feb 2024 · 5,368 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite