54 articles for “T lymphocytes”

Research ArticleOpen accessIn the abstractEvaluation of the Immunomodulatory Properties of a Calf Lipid Thymus Extract and Standardization of a Method for Quantification of its Biological ActivityMiodrag Colic, Radmila Popovic, Dusanka Mrdakovic et al.The aim of this study was to test the immunobiological properties of a new formulation of the lipid thymus calf extract (Thymsol), prepared for in vitro cell culture experiments. At first, we showed that Thymsol enhanced the antigen specific immune response in AO rats in vitro, using Keyhole limpet hemocyanin (KLH). At lower concentrations (0.5-2.5 Î¼g mL-1) the extract increased … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 7,039 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCirculating Granzymes are associated with Bloodstream Infection and Death in Febrile Medical PatientsAnnelies N. Tacx, Angela M. Wolbink, C. E. Hack, A.B. Johan GroeneveldPlasma levels of granzymes are specific markers for the activation of cytotoxic T lymphocytes and natural killer (NK) cells but the impact of activation of these cells on the course of bacterial infections is not well understood. We prospectively studied the implications of circulating granzyme A and B (GrA, GrB) levels in febrile, medical and hospitalized patients (n=284), during 3 … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 6,736 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Changing Pathology of NeuroAIDS Associated with Drug Abuse in the Era of HAARTE Bell Jeanne, C. Anthony Iain, Simmonds PeterCompliance with highly active antiretroviral therapy (HAART) arrests HIV induced immune collapse and reduces the prevalence of severe central nervous system (CNS) complications, including HIV associated dementia and encephalitis. However minor cognitive disorders remain common and recent autopsy studies have demonstrated the presence of subtle neuropathological abnormalities in HAART treated individuals, including persistent neuroinflammation and enhanced deposition in the brain … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,872 accessesView PDF Cite

Research ArticleOpen accessIn the abstractLeishmania donovani: Immunomodulatory Role of 63KDa Leishmania Antigen in the Promotion of IFN-gamma Response (VL vs HIV-VL Co-infection)Pranati, Sanjiva Bimal, K. Pandey et al.Cytokine behavior of T-lymphocytes is not very clear when a patient is co-infected with Leishmania donovani and HIV. To achieve this we studied groups of patients comprising of VL infected, HIV infected and HIV-VL co-infected cases. As compared to lone infections by either of the infecting agent, the co-infection cases showed greatly diminished CD4 T-cell counts and slightly enhanced values … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 7,000 accessesView PDF Cite